Piri Keşif Aracı

1

Liver injury in COVID-19 – The culprit may not be COVID-19!

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Journal of Hepatology

Yayıncı:

Elsevier BV

Yazar(lar) :

Aditya Singh , Madhumita Premkumar , Virendra Singh

Yıl :

2021

Liver injury in COVID-19 – The culprit may not be COVID-19!

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DOI : 10.1016/j.jhep.2021.03.010

ISSN: 0168-8278
Sayı: 3
Cilt: 75
Sayfa: 739-740

Sınıflandırma :

Biyotıp %53

Görüntüleme ve Radyoloji %100

Tıp ve Halk Sağlığı %47

Kardiyoloji %50

2

Are children less susceptible to COVID-19?

Dergi Makalesi

Kaynak 1:

Directory of Open Access Journals (DOAJ)

Kaynak 2:

Science Direct

Dergi:

Journal of Microbiology, Immunology and Infection

Yazar(lar) :

Ping-Ing Lee , Ya-Li Hu , Po-Yen Chen , Yhu-Chering Huang , Po-Ren Hsueh

Yıl :

2020

Are children less susceptible to COVID-19?

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Kaynak 1:

http://www.sciencedirect.com/science/article/pii/S1684118220300396 arayıcılığı görüntüle.
Kaynak 2:

http://dx.doi.org/10.1016/j.jmii.2020.02.011 arayıcılığı görüntüle.

ISSN: 1684-1182
Cilt: 53
Sayı: 3
Sayfa: 371 - 372

Sınıflandırma :

Biyotıp %56

Görüntüleme ve Radyoloji %100

Yaşam Bilimleri %19

Tıbbi Mikrobiyoloji %32

Biyoçeşitlilik %26

3

Neurological manifestations in COVID-19: A narrative review

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

SAGE Open Medicine

Yazar(lar) :

Asma Rahman , Roshan Niloofa , Ishan M De Zoysa , Akila D Cooray , Jayani Kariyawasam , Suranjith L Seneviratne

Yıl :

2020

Neurological manifestations in COVID-19: A narrative review COVID- 19, a respiratory viral infection, has affected more than 10 million individuals worldwide. We have outlined the common neurological manifestations in COVID- 19 (information are up-to-date as of June 2020) and discussed the possible pathogenetic

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COVID-19, a respiratory viral infection, has affected more than 10 million individuals worldwide. Common symptoms include fever, dry cough, fatigue and shortness of breath. Some patients show neurological manifestations such as headache, dizziness, cerebrovascular disease, peripheral nerve and muscle symptoms and smell and taste impairment. In previous studies, SARS-CoV-1 and MERS-CoV were found to affect the nervous system. Given the high similarity between SARS-CoV-1 and SARS-CoV-2, effects on the nervous system by SARS-CoV-2 are a possibility. We have outlined the common neurological manifestations in COVID-19 (information are up-to-date as of June 2020) and discussed the possible pathogenetic mechanisms and management options.

DOI : 10.1177/2050312120957925

ISSN: 2050-3121
Cilt: 8

Sınıflandırma :

Biyotıp %92

Görüntüleme ve Radyoloji %31

Gen Fonksiyonu %19

4

Myasthenic crisis in COVID-19

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Journal of the Neurological Sciences

Yayıncı:

Elsevier

Yazar(lar) :

Fadi Delly , Maryam J. Syed , Robert P. Lisak , Deepti Zutshi

Yıl :

2020

Myasthenic crisis in COVID-19 COVID-19

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DOI : 10.1016/j.jns.2020.116888

Anahtar Kelimeler : Viral infection, Myasthenia, COVID-19

ISSN: 0022-510X
Cilt: 414
Sayfa: 116888

Sınıflandırma :

Biyotıp %100

Epidemiyoloji %36

Görüntüleme ve Radyoloji %27

Reseptörler %25

5

COVID-19: the novel SARS-CoV-2 pandemic

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

Revista Peruana de Medicina Experimental y Salud Pública

Yazar(lar) :

Roberto Alfonso Accinelli , Cristian Mingxiong Zhang Xu , Jia-Der Ju Wang , José Miguel Yachachin-Chávez , Jaime Augusto Cáceres-Pizarro , Karla Beatriz Tafur-Bances , Roberto Gabriel Flores-Tejada , Alejandra del Carmen Paiva-Andrade

Yıl :

2020

COVID-19: the novel SARS-CoV-2 pandemic

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During the first weeks of 2020, cases of SARS-CoV-2 began to be reported outside of China, with a rapid increase in cases and deaths worldwide. SARS-CoV-2 is a positive single-stranded RNA virus, encased in a lipid bilayer derived from the host cell membrane and consists of four structural proteins (S, M, E and N), plus a haemagglutinin-sterase. The binding of the S protein to the ECA2 receptor allows the entry of the virus into the host cell and is a potential therapeutic target. 81% of patients develop mild symptoms, 14% have severe symptoms and 5% require intensive care management. Fever is the most frequent symptom, followed by cough and dyspnea. Most patients do not present leukocytosis, but they do present lymphopenia with sputum cultures that do not show other pathogens. In lung biopsies of severe patients, the most noticeable finding is diffuse alveolar damage. Radiologically, ground glass and alveolar patterns are observed; the lesions being predominantly basal, subpleural, and posterior, with a multifocal peripheral distribution, more affecting the right lower lobe. There is a marked inflammatory response, up to the cytokine storm, in which anti-inflammatory treatment with pulse therapy with methylprednisolone would be indicated. Although there are no large-scale studies regarding the use of chloroquine / hydroxychloroquine, due to the global situation, its use has been authorized for its anti-SARS-CoV-2 and anti-inflammatory effect, which can be potentiated with the use of azithromycin.

DOI : 10.17843/rpmesp.2020.372.5411

Anahtar Kelimeler : síndrome respiratorio agudo grave, neumonía viral, infecciones por coronavirus, pandemia

Cilt: 37
Sayı: 2
Sayfa: 302 - 11

Sınıflandırma :

Biyotıp %64

Görüntüleme ve Radyoloji %57

Tıp ve Halk Sağlığı %36

Pnömoloji ve Solunum Sistemi %44

6

Liver Injury in COVID-19: Caution and Management

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

Liver Cancer

Yazar(lar) :

Jiasheng Cao , Xiujun Cai , Mingyu Chen

Yıl :

2020

Liver Injury in COVID-19: Caution and Management

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DOI : 10.1159/000508696

Sayfa: 1 - 2

Sınıflandırma :

Biyotıp %76

Görüntüleme ve Radyoloji %87

Tıp ve Halk Sağlığı %23

Hepatoloji %33

Abdominal Cerrahi %31

7

Hypoalbuminemia in COVID‐19

Dergi Makalesi

Kaynak :

Wiley Online Library

Dergi:

Journal of Internal Medicine

Yazar(lar) :

D. Lapenna

Yıl :

2021

Hypoalbuminemia in COVID‐19

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DOI : 10.1111/joim.13403

ISSN: 0954-6820

Sınıflandırma :

Biyotıp %100

Görüntüleme ve Radyoloji %100

8

Syncope, Brugada syndrome, and COVID‐19 lung disease

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

Journal of Arrhythmia

Yazar(lar) :

Giampaolo Pasquetto , Giovanni Battista Conti , Angela Susana , Lucia Anna Leone , Emanuele Bertaglia

Yıl :

2020

Syncope, Brugada syndrome, and COVID‐19 lung disease COVID‐19 lung disease

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Abstract A 52‐year‐old male with no history of familiar sudden death arrived at our Emergency Department after syncope with loss of consciousness occurred during high fever. The thoracic high‐resolution computed tomography demonstrated bilateral multiple ground‐glass opacities. The nose‐pharyngeal swab resulted positive for SARS‐CoV‐2. The 12‐lead ECG presented a “coved‐type” aspect in leads V1 and V2 at the fourth intercostal space and a first degree atrio‐ventricular block. As soon as the temperature went down, the 12‐lead ECG resumed a normal aspect, maintaining a long PR interval.

DOI : 10.1002/joa3.12375

Anahtar Kelimeler : Brugada syndrome, COVIDu201019 lung disease, fever

Cilt: 36
Sayı: 4
Sayfa: 768 - 770

Sınıflandırma :

Tıp ve Halk Sağlığı %68

Kardiyoloji %88

Biyotıp %32

Görüntüleme ve Radyoloji %67

Biyomedikal Mühendisliği ve Biyomühendislik %20

9

Chronotherapy in COVID-19 Disease

Dergi Makalesi

Kaynak :

Springer Link

Dergi:

Journal of General Internal Medicine

Yazar(lar) :

Alexis LACOUT , Pierre Yves MARCY , Christian PERRONNE

Konu :

Internal Medicine

Yıl :

2021

Chronotherapy in COVID-19 Disease

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DOI : 10.1007/s11606-021-06719-3

ISSN: 0884-8734 1525-1497
Sayı: 8
Cilt: 36
Sayfa: 2466-2467

Sınıflandırma :

Biyotıp %98

Biyotıp %67

Görüntüleme ve Radyoloji %30

10

Corona (COVID-19) time musings: Our involvement in COVID-19 pathogenesis, diagnosis, treatment and vaccine planning

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Autoimmunity Reviews

Yayıncı:

Elsevier

Yazar(lar) :

Yehuda Shoenfeld

Yıl :

2020

Corona (COVID-19) time musings: Our involvement in COVID-19 pathogenesis, diagnosis, treatment and vaccine planning

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DOI : 10.1016/j.autrev.2020.102538

ISSN: 1568-9972
Sayı: 6
Cilt: 19
Sayfa: 102538

Sınıflandırma :

Biyotıp %84

Görüntüleme ve Radyoloji %52

Biyomedikal Mühendisliği ve Biyomühendislik %27

11

Current regulatory approaches for accessing potential COVID-19 therapies

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

Journal of Pharmaceutical Policy and Practice

Yazar(lar) :

Vesa Halimi , Armond Daci , Simona Stojanovska , Irina Panovska-Stavridis , Milena Stevanovic , Venko Filipce , Aleksandra Grozdanova

Yıl :

2020

Current regulatory approaches for accessing potential COVID-19 therapies Abstract This commentary aims to elaborate challenges in the regulatory approaches for accessing and investigating COVID- 19 potential therapies either COVID-19

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Abstract This commentary aims to elaborate challenges in the regulatory approaches for accessing and investigating COVID-19 potential therapies either with off-label use, compassionate use, emergency use or for clinical trials. Since no therapies have been formally approved and completely effective and safe to date, the best clinical choice is acquired only after consistent and fair communication and collaboration between licensed clinicians, researchers, regulatory authorities, manufacturers and patients.

DOI : 10.1186/s40545-020-00222-6

Anahtar Kelimeler : COVID-19, Regulatory, Clinical studies, Compassionate use

ISSN: 2052-3211
Cilt: 13
Sayı: 1
Sayfa: 1 - 4

Sınıflandırma :

Biyotıp %46

Görüntüleme ve Radyoloji %30

Tıp ve Halk Sağlığı %33

12

Features of anosmia in COVID-19

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Médecine et Maladies Infectieuses

Yayıncı:

Elsevier

Yazar(lar) :

T. Klopfenstein , N.J. Kadiane-Oussou , L. Toko , P.-Y. Royer , Q. Lepiller , V. Gendrin , S. Zayet

Yıl :

2020

Features of anosmia in COVID-19 Background Medical publications about anosmia with COVID- 19 are scarce. We aimed to describe the prevalence and features of anosmia in COVID- 19 patients. Results Fifty-four of 114 patients (47%) with confirmed COVID- 19 reported anosmia. COVID-19

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Background Medical publications about anosmia with COVID-19 are scarce. We aimed to describe the prevalence and features of anosmia in COVID-19 patients. Methods We retrospectively included COVID-19 patients with anosmia between March 1st and March 17th, 2020. We used SARS-CoV-2 real time PCR in respiratory samples to confirm the cases. Results Fifty-four of 114 patients (47%) with confirmed COVID-19 reported anosmia. Mean age of the 54 patients was 47 (± 16) years; 67% were females and 37% were hospitalised. The median Charlson comorbidity index was 0.70 (± 1.6 [0–7]). Forty-six patients (85%) had dysgeusia and 28% presented with pneumonia. Anosmia began 4.4 (± 1.9 [1–8]) days after infection onset. The mean duration of anosmia was 8.9 (± 6.3 [1–21]) days and 98% of patients recovered within 28 days. Conclusions Anosmia was present in half of our European COVID-19 patients and was often associated with dysgeusia.

DOI : 10.1016/j.medmal.2020.04.006

Anahtar Kelimeler : COVID-19, Anosmia, Dysgeusia

ISSN: 0399-077X
Sayı: 5
Cilt: 50
Sayfa: 436-439

Sınıflandırma :

Biyotıp %90

Görüntüleme ve Radyoloji %56

Translasyon Sonrası Değişiklik %40

13

Low-Dose Radiotherapy for Late-Stage COVID-19 Pneumonia?

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

Dose-Response

Yazar(lar) :

Michael I. Koukourakis

Yıl :

2020

Low-Dose Radiotherapy for Late-Stage COVID-19 Pneumonia? The unimaginable daily death toll of thousands of victims dying from COVID- 19 pneumonia and the marginal therapeutic value of agents tested, brings forward the re-evaluation of the position of radiotherapy in the treatment of late stage lethal COVID-induced respiratory failure. Whether radiotherapy, in conjunction with remdesivir and/or macrolides can reduce the dramatic death rates related to COVID- 19 is an open challenge, under

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Low dose radiotherapy has been used in the pre-antibiotic era for the treatment of all kind of pneumonia, with relative success. The unimaginable daily death toll of thousands of victims dying from COVID-19 pneumonia and the marginal therapeutic value of agents tested, brings forward the re-evaluation of the position of radiotherapy in the treatment of late stage lethal COVID-induced respiratory failure. A sound biological rationale supports this idea. Immunopathology studies show that excessive inflammation and infiltration of the lung parenchyma by immune cells is the cause of death. Mice lacking IFNαβ receptors remain unaffected by the virus. Radiotherapy at doses of 50-200cG may exert an intense anti-inflammatory effect and reduce the burden of inflammatory cells infiltrating the lungs. Whether radiotherapy, in conjunction with remdesivir and/or macrolides can reduce the dramatic death rates related to COVID-19 is an open challenge, under the absence of an alternative solution.

DOI : 10.1177/1559325820951357

ISSN: 1559-3258
Cilt: 18

Sınıflandırma :

Biyotıp %100

Görüntüleme ve Radyoloji %26

14

Safety of an immunomodulator Mycobacterium w in COVID-19

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

Lung India

Yazar(lar) :

Inderpaul Singh Sehgal , Ashish Bhalla , Goverdhan Dutt Puri , Laxmi Narayana Yaddanapudi , Mini Singh , Pankaj Malhotra , Sahajal Dhooria , Vikas Suri , Ritesh Agarwal

Yıl :

2020

Safety of an immunomodulator Mycobacterium w in COVID-19

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DOI : 10.4103/lungindia.lungindia_242_20

Cilt: 37
Sayı: 3
Sayfa: 279 - 281

Sınıflandırma :

Biyotıp %97

Translasyon Sonrası Değişiklik %38

Görüntüleme ve Radyoloji %33

15

Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

Frontiers in Immunology

Yazar(lar) :

Jun Wang , Jun Wang , Jun Wang , Qian Li , Qian Li , Yongmei Yin , Yingying Zhang , Yingying Cao , Xiaoming Lin , Lihua Huang , Lihua Huang , Daniel Hoffmann , Mengji Lu , Yuanwang Qiu , Yuanwang Qiu , Yuanwang Qiu

Yıl :

2020

Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19 Background: Cases of excessive neutrophil counts in the blood in severe coronavirus disease ( COVID- 19) patients have drawn significant attention. It is urgent to clarify the pathogenesis of neutrophils leading to severe pneumonia in COVID- 19.Methods: A retrospective analysis was performed on 55 COVID Transcriptome analysis revealed that neutrophil activation was correlated with 17 neutrophil extracellular trap (NET)-associated genes in COVID- 19 patients COVID-19

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Background: Cases of excessive neutrophil counts in the blood in severe coronavirus disease (COVID-19) patients have drawn significant attention. Neutrophil infiltration was also noted on the pathological findings from autopsies. It is urgent to clarify the pathogenesis of neutrophils leading to severe pneumonia in COVID-19.Methods: A retrospective analysis was performed on 55 COVID-19 patients classified as mild (n = 22), moderate (n = 25), and severe (n = 8) according to the Guidelines released by the National Health Commission of China. Trends relating leukocyte counts and lungs examined by chest CT scan were quantified by Bayesian inference. Transcriptional signatures of host immune cells of four COVID19 patients were analyzed by RNA sequencing of lung specimens and BALF.Results: Neutrophilia occurred in 6 of 8 severe patients at 7–19 days after symptom onset, coinciding with lesion progression. Increasing neutrophil counts paralleled lesion CT values (slope: 0.8 and 0.3–1.2), reflecting neutrophilia-induced lung injury in severe patients. Transcriptome analysis revealed that neutrophil activation was correlated with 17 neutrophil extracellular trap (NET)-associated genes in COVID-19 patients, which was related to innate immunity and interacted with T/NK/B cells, as supported by a protein–protein interaction network analysis.Conclusion: Excessive neutrophils and associated NETs could explain the pathogenesis of lung injury in COVID-19 pneumonia.

DOI : 10.3389/fimmu.2020.02063

Anahtar Kelimeler : coronavirus, COVID-19, neutrophil extracellular trap, pneumonia, neutrophilia, lymphopenia

ISSN: 1664-3224
Cilt: 11

Sınıflandırma :

Biyotıp %64

Hematoloji %65

Görüntüleme ve Radyoloji %25

Tıp ve Halk Sağlığı %36

Pnömoloji ve Solunum Sistemi %40

İmmünoloji %35

Yoğun ve Yoğun Bakım Tıbbı %22

16

Ozone Therapy as a Possible Option in COVID-19 Management

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

Frontiers in Public Health

Yazar(lar) :

Alessandra Gavazza , Andrea Marchegiani , Giacomo Rossi , Marianno Franzini , Marianno Franzini , Andrea Spaterna , Sara Mangiaterra , Matteo Cerquetella

Yıl :

2020

Ozone Therapy as a Possible Option in COVID-19 Management COVID-19

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DOI : 10.3389/fpubh.2020.00417

Anahtar Kelimeler : COVID-19, ozone, public health, SARS-CoV-2, therapy

ISSN: 2296-2565
Cilt: 8

Sınıflandırma :

Tıp ve Halk Sağlığı %56

Halk Sağlığı %40

Biyotıp %21

Görüntüleme ve Radyoloji %51

17

COVID-19-associated delayed posthypoxic necrotizing leukoencephalopathy

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Journal of the Neurological Sciences

Yayıncı:

Elsevier

Yazar(lar) :

Alireza Radmanesh , Anna Derman , Koto Ishida

Yıl :

2020

COVID-19-associated delayed posthypoxic necrotizing leukoencephalopathy

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DOI : 10.1016/j.jns.2020.116945

ISSN: 0022-510X
Cilt: 415
Sayfa: 116945

Sınıflandırma :

Biyotıp %100

Biyotıp %60

Görüntüleme ve Radyoloji %24

18

Predictors of intracerebral hemorrhage in COVID-19

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Journal of Clinical Neuroscience

Yayıncı:

Elsevier BV

Yazar(lar) :

Yoshimi Shinohara , Ryo Miyaoka , Makoto Hirosawa , Junkoh Yamamoto

Yıl :

2021

Predictors of intracerebral hemorrhage in COVID-19 COVID-19

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DOI : 10.1016/j.jocn.2021.01.031

Anahtar Kelimeler : COVID-19, SARS-CoV-2, Intracerebral hemorrhage, Anticoagulation, Coagulopathy

ISSN: 0967-5868
Cilt: 86
Sayfa: 368-369

Sınıflandırma :

Biyotıp %66

Görüntüleme ve Radyoloji %99

Tıp ve Halk Sağlığı %34

Nöroşirürji %41

19

Thromboinflammation in COVID-19 acute lung injury

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Paediatric Respiratory Reviews

Yayıncı:

Elsevier

Yazar(lar) :

William Beau Mitchell

Yıl :

2020

Thromboinflammation in COVID-19 acute lung injury COVID- 19 also presents with a severe coagulopathy with a high rate of venous thromboembiolism. In our experience as a COVID- 19 epicenter, children and young adults do develop both the coagulopathy and the ALI of COVID- 19. This review will discuss COVID- 19 ALI from a hematological perspective with discussion of the distinct aspects of coagulation that are apparent in COVID COVID-19

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Since the initial description in 2019, the novel coronavirus SARS-Cov-2 infection (COVID-19) pandemic has swept the globe. The most severe form of the disease presents with fever and shortness of breath, which rapidly deteriorates to respiratory failure and acute lung injury (ALI). COVID-19 also presents with a severe coagulopathy with a high rate of venous thromboembiolism. In addition, autopsy studies have revealed co-localized thrombosis and inflammation, which is the signature of thromboinflammation, within the pulmonary capillary vasculature. While the majority of published data is on adult patients, there are parallels to pediatric patients. In our experience as a COVID-19 epicenter, children and young adults do develop both the coagulopathy and the ALI of COVID-19. This review will discuss COVID-19 ALI from a hematological perspective with discussion of the distinct aspects of coagulation that are apparent in COVID-19. Current and potential interventions targeting the multiple thromboinflammatory mechanisms will be discussed.

DOI : 10.1016/j.prrv.2020.06.004

Anahtar Kelimeler : COVID-19, Acute lung injury, Thrombosis, Inflammation

ISSN: 1526-0542
Cilt: 35
Sayfa: 20-24

Sınıflandırma :

Biyotıp %53

Gen Fonksiyonu %72

Görüntüleme ve Radyoloji %27

Tıp ve Halk Sağlığı %47

Yoğun ve Yoğun Bakım Tıbbı %57

Pnömoloji ve Solunum Sistemi %26

20

Iron: Innocent bystander or vicious culprit in COVID-19 pathogenesis?

Dergi Makalesi

Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

International Journal of Infectious Diseases

Yazar(lar) :

Marvin Edeas , Jumana Saleh , Carole Peyssonnaux

Yıl :

2020

Iron: Innocent bystander or vicious culprit in COVID-19 pathogenesis? Current management of COVID- 19 is based on the premise that respiratory failure is the leading cause of mortality. However, mounting evidence links accelerated pathogenesis in gravely ill COVID- 19 patients to a hyper-inflammatory state involving a cytokine storm. In spite of its strong association with mortality, it is not yet clear if hyper-ferritinemia in COVID- 19 patients is merely a systemic marker of disease

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The coronavirus 2 (SARS-CoV-2) pandemic is viciously spreading through the continents with rapidly increasing mortality rates. Current management of COVID-19 is based on the premise that respiratory failure is the leading cause of mortality. However, mounting evidence links accelerated pathogenesis in gravely ill COVID-19 patients to a hyper-inflammatory state involving a cytokine storm. Several components of the heightened inflammatory state were addressed as therapeutic targets. Another key component of the heightened inflammatory state is hyper-ferritinemia which reportedly identifies patients with increased mortality risk. In spite of its strong association with mortality, it is not yet clear if hyper-ferritinemia in COVID-19 patients is merely a systemic marker of disease progression, or a key modulator in disease pathogenesis. Here we address implications of a possible role for hyper-ferritinemia, and altered iron homeostasis in COVID-19 pathogenesis, and potential therapeutic targets in this regard.

Anahtar Kelimeler : Hyper-ferritinemia, Hypercoagulability, Iron homeostasis, Ferroptosis, Oxidative stress, Mitochondria

Cilt: 97
Sayfa: 303 - 305

Sınıflandırma :

Biyotıp %78

Görüntüleme ve Radyoloji %22

Tıp ve Halk Sağlığı %22

İmmünoloji %87

21

COVID-19 and Cerebral Hemorrhage: Proposed Mechanisms

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Journal of Neuroradiology

Yayıncı:

Elsevier

Yazar(lar) :

Mohamad Syafeeq Faeez Md Noh

Yıl :

2020

COVID-19 and Cerebral Hemorrhage: Proposed Mechanisms

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DOI : 10.1016/j.neurad.2020.05.007

ISSN: 0150-9861

Sınıflandırma :

Biyotıp %100

Görüntüleme ve Radyoloji %92

22

Erythema multiforme in COVID‐19 patients and following COVID‐19 vaccination: manifestations, associations and outcomes

Dergi Makalesi

Kaynak :

Wiley Online Library

Dergi:

Journal of the European Academy of Dermatology and Venereology

Yazar(lar) :

F. Etaee , M. Eftekharian , T. Naguib , S. Daveluy

Yıl :

2022

Erythema multiforme in COVID‐19 patients and following COVID‐19 vaccination: manifestations, associations and outcomes

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DOI : 10.1111/jdv.18063

ISSN: 0926-9959

Sınıflandırma :

Tıp ve Halk Sağlığı %67

Dermatoloji %31

Kulak Burun Boğaz Hastalıkları %26

Biyotıp %33

Görüntüleme ve Radyoloji %67

23

EEG findings in COVID-19 related encephalopathy

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Clinical Neurophysiology

Yayıncı:

Elsevier

Yazar(lar) :

Elena Pasini , Francesca Bisulli , Lilia Volpi , Irene Minardi , Maria Tappatà , Lorenzo Muccioli , Umberto Pensato , Patrizia Riguzzi , Paolo Tinuper , Roberto Michelucci

Yıl :

2020

EEG findings in COVID-19 related encephalopathy

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DOI : 10.1016/j.clinph.2020.07.003

ISSN: 1388-2457
Sayı: 9
Cilt: 131
Sayfa: 2265-2267

Sınıflandırma :

Biyotıp %97

Görüntüleme ve Radyoloji %83

24

Ivermectin in COVID-19. Argumentun ad ignorantiam?

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Revista Clínica Española (English Edition)

Yayıncı:

Elsevier

Yazar(lar) :

Y. Carlosama-Rosero

Yıl :

2020

Ivermectin in COVID-19. Argumentun ad ignorantiam?

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DOI : 10.1016/j.rceng.2020.06.003

ISSN: 2254-8874
Sayı: 7
Cilt: 220
Sayfa: 457-458

Sınıflandırma :

Dilbilim %68

Çok Dillilik %100

Biyotıp %24

Tropik ilaç %64

Görüntüleme ve Radyoloji %31

25

Hemorrhagic stroke and anticoagulation in COVID-19

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Journal of Stroke and Cerebrovascular Diseases

Yayıncı:

Elsevier

Yazar(lar) :

Siddhant Dogra , Rajan Jain , Meng Cao , Seda Bilaloglu , David Zagzag , Sarah Hochman , Ariane Lewis , Kara Melmed , Katherine Hochman , Leora Horwitz , Steven Galetta , Jeffrey Berger

Yıl :

2020

Hemorrhagic stroke and anticoagulation in COVID-19 Background and Purpose Patients with the Coronavirus Disease of 2019 ( COVID- 19) are at increased risk for thrombotic events and mortality. Methods Patients over the age of 18 with confirmed COVID- 19 and radiographic evidence of ICH were included in this study. Results We identified 33 COVID- 19 positive patients with ICH, mean age 61.6 years (range 37–83 years), 21.2% of whom were female. COVID-19

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Background and Purpose Patients with the Coronavirus Disease of 2019 (COVID-19) are at increased risk for thrombotic events and mortality. Various anticoagulation regimens are now being considered for these patients. Anticoagulation is known to increase the risk for adverse bleeding events, of which intracranial hemorrhage (ICH) is one of the most feared. We present a retrospective study of 33 patients positive for COVID-19 with neuroimaging-documented ICH and examine anticoagulation use in this population. Methods Patients over the age of 18 with confirmed COVID-19 and radiographic evidence of ICH were included in this study. Evidence of hemorrhage was confirmed and categorized by a fellowship trained neuroradiologist. Electronic health records were analyzed for patient information including demographic data, medical history, hospital course, laboratory values, and medications. Results We identified 33 COVID-19 positive patients with ICH, mean age 61.6 years (range 37–83 years), 21.2% of whom were female. Parenchymal hemorrhages with mass effect and herniation occurred in 5 (15.2%) patients, with a 100% mortality rate. Of the remaining 28 patients with ICH, 7 (25%) had punctate hemorrhages, 17 (60.7%) had small- moderate size hemorrhages, and 4 (14.3%) had a large single site of hemorrhage without evidence of herniation. Almost all patients received either therapeutic dose anticoagulation (in 22 [66.7%] patients) or prophylactic dose (in 3 [9.1] patients) prior to ICH discovery. Conclusions Anticoagulation therapy may be considered in patients with COVID-19 though the risk of ICH should be taken into account when developing a treatment regimen.

DOI : 10.1016/j.jstrokecerebrovasdis.2020.104984

Anahtar Kelimeler : COVID-19, Intracranial hemorrhage, Anticoagulation, Hemorrhagic stroke

ISSN: 1052-3057
Sayı: 8
Cilt: 29
Sayfa: 104984

Sınıflandırma :

Biyotıp %96

Hematoloji %43

Görüntüleme ve Radyoloji %42

26

Rethinking high-risk groups in COVID-19

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Multiple Sclerosis and Related Disorders

Yayıncı:

Elsevier

Yazar(lar) :

Anastasia Vishnevetsky , Michael Levy

Yıl :

2020

Rethinking high-risk groups in COVID-19 COVID-19

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DOI : 10.1016/j.msard.2020.102139

Anahtar Kelimeler : Coronavirus, COVID-19, High risk, Immunocompromised, Elderly

ISSN: 2211-0348
Cilt: 42
Sayfa: 102139

Sınıflandırma :

Tıp ve Halk Sağlığı %61

Kulak Burun Boğaz Hastalıkları %39

Biyotıp %28

Görüntüleme ve Radyoloji %41

Epidemiyoloji %27

27

Spectrum of neuropsychiatric manifestations in COVID-19

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Brain, Behavior, and Immunity

Yayıncı:

Elsevier

Yazar(lar) :

Krishna Nalleballe , Sanjeeva Reddy Onteddu , Rohan Sharma , Vasuki Dandu , Aliza Brown , Madhu Jasti , Sisira Yadala , Karthika Veerapaneni , Suman Siddamreddy , Akshay Avula , Nidhi Kapoor , Kamran Mudassar , Sukanthi Kovvuru

Yıl :

2020

Spectrum of neuropsychiatric manifestations in COVID-19 Corona Virus Disease 2019 ( COVID- 19) emerged in December 2019 from Wuhan, China. We analyzed COVID- 19 adult patients in the TriNetX database, which is a global health collaborative clinical research platform collecting real-time electronic - 19 among whom 9086 (22.5%) patients had neuropsychiatric manifestations.

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Corona Virus Disease 2019 (COVID-19) emerged in December 2019 from Wuhan, China. It typically presents with mild upper respiratory tract infection symptoms and may have life threatening complications, including acute respiratory distress syndrome, acute stroke, myocardial infarction, kidney failure, shock, and even death. Coronavirus infections are known to have neuroinvasive potential with consequent neuropsychiatric manifestations. We analyzed COVID-19 adult patients in the TriNetX database, which is a global health collaborative clinical research platform collecting real-time electronic medical records data from a network of health care organizations (HCOs) from January 20, 2020 to June 10th, 2020. 40,469 patients were diagnosed with COVID-19 among whom 9086 (22.5%) patients had neuropsychiatric manifestations. The most common neurologic manifestations included headache (3.7%) and sleep disorders (3.4%), Encephalopathy (2.3%), Stroke and transient ischemic attack (TIA) (1.0%) and 0.6% had seizures. Most common psychiatric manifestations included anxiety and other related disorders (4.6%), mood disorders (3.8%), while 0.2% patients had suicidal ideation. Early recognition and prompt management of neuropsychiatric manifestations in these patients have a potential to decrease overall morbidity and mortality.

DOI : 10.1016/j.bbi.2020.06.020

ISSN: 0889-1591
Cilt: 88
Sayfa: 71-74

Sınıflandırma :

Biyotıp %98

Görüntüleme ve Radyoloji %32

28

A cautionary tale of false-negative nasopharyngeal COVID-19 testing

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Kaynak :

Directory of Open Access Journals (DOAJ)

Dergi:

IDCases

Yazar(lar) :

Sean S.M. Bullis , Jessica W. Crothers , Shawn Wayne , Andrew J. Hale

Yıl :

2020

A cautionary tale of false-negative nasopharyngeal COVID-19 testing Serial testing for COVID- 19 is indicated in patients with high pretest probability of disease. COVID-19

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There remains diagnostic uncertainty regarding the sensitivity of reverse transcription polymerase chain reaction in detection of SARS-CoV-2 from nasopharyngeal specimens. We present a case where two nasopharyngeal specimens were negative, followed by a positive sputum sample. Serial testing for COVID-19 is indicated in patients with high pretest probability of disease.

Anahtar Kelimeler : SARS-CoV-2, COVID-19, Nasopharyngeal swab

ISSN: 2214-2509
Cilt: 20
Sayfa: e00791

Sınıflandırma :

Biyotıp %92

Görüntüleme ve Radyoloji %62

Biyomedikal Mühendisliği ve Biyomühendislik %24

29

Nebulized Lidocaine in COVID-19, An Hypothesis

Dergi Makalesi

Kaynak :

Science Direct

Dergi:

Medical Hypotheses

Yayıncı:

Elsevier

Yazar(lar) :

Ziad A. Ali , Rif S. El-Mallakh

Yıl :

2020

Nebulized Lidocaine in COVID-19, An Hypothesis Coronavirus Diseases-2019 ( COVID- 19) has caused a large global outbreak and has been declared as a pandemic by the World Health Organization (WHO). It has been proposed that COVID- 19-related hyperinflammation and dysregulated immune response might play a critical role in developing a cytokine storm It is proposed that nebulized lidocaine might be beneficial in reducing cytokines, protecting patients’ lungs and improving outcomes in COVID- 19 patients COVID-19

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Coronavirus Diseases-2019 (COVID-19) has caused a large global outbreak and has been declared as a pandemic by the World Health Organization (WHO). It has been proposed that COVID-19-related hyperinflammation and dysregulated immune response might play a critical role in developing a cytokine storm which usually progresses to a life-threatening acute lung injury or acute respiratory distress syndrome in infected individuals. Lidocaine, a local analgesic and anti-arrhythmic, is known for its anti-inflammatory actions and has been used to reduce cough and improve respiratory symptoms in severe asthmatic patients. It has a demonstrated safety profile. It is proposed that nebulized lidocaine might be beneficial in reducing cytokines, protecting patients’ lungs and improving outcomes in COVID-19 patients when administered via inhalation as an adjunctive treatment for severe respiratory symptoms in patients fighting the novel Coronavirus. Additional investigation is warranted.

DOI : 10.1016/j.mehy.2020.109947

Anahtar Kelimeler : Lidocaine, COVID-19, SARS-CoV-2, Cytokine-storm, Anti-inflammatories

ISSN: 0306-9877
Cilt: 144
Sayfa: 109947

Sınıflandırma :

Biyotıp %98

Görüntüleme ve Radyoloji %74

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