• Piri Keşif Aracı

Arama ipuçları nelerdir?
1.  sayfa ve
1
COVID-19 Vaccines : A literature analysis of the three first approved COVID-19 Vaccines in the EU
Tez

Tez
Kaynak :
NDTLD Thesis
Yazar(lar) :
Morgan Persson
Yıl :
2021
COVID-19 Vaccines : A literature analysis of the three first approved COVID-19 Vaccines in the EU
Yayıncı Web Sitesi
Kaydet
Anahtar Kelimeler : Basic Medicine
Sınıflandırma :
2
Asymptomatic COVID-19 Infection Management: The Key to Stop COVID-19
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Journal of Clinical and Experimental Investigations
Yazar(lar) :
Rachid Ait Addi , Abdelhafid Benksim , Mohamed Amine , Mohamed Cherkaoui
Yıl :
2020
Asymptomatic COVID-19 Infection Management: The Key to Stop COVID-19 The COVID- 19 disease, emerged in December 2019, has spread rapidly, with new cases confirmed in multiple countries. portion of the population to virus and increase the late diagnosis and thereafter enhance COVID- 19 mortality. Thereafter, it is fundamental to review our COVID- 19 screening approach and enlarge COVID- 19 testing to the general population by using rapid testing appliances COVID-19
Yayıncı Web Sitesi
Tam Metin
Kaydet
The COVID-19 disease, emerged in December 2019, has spread rapidly, with new cases confirmed in multiple countries. Many efforts to contain the virus are ongoing, such as containment, individual measures of protection, the authorization of use of some drugs as chloquorine in some countries. Also, it has been known that symptomatic and asymptomatic people whom are infected by COVID-19 have the same contagiousness which expose a far greater portion of the population to virus and increase the late diagnosis and thereafter enhance COVID-19 mortality. Thereafter, it is fundamental to review our COVID-19 screening approach and enlarge COVID-19 testing to the general population by using rapid testing appliances such as rapid SARS-CoV-2 IgG-IgM combined antibody since another appliance more efficient will be performed.
DOI : 10.5799/jcei/7866
Anahtar Kelimeler : COVID-19, pandemic, screening, diagnosis
Cilt: 11
Sayı: 3
Sayfa:
Sınıflandırma :
3
Covid-19 Pandemic-Insights and Challenges
e-Kitap

e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Internet Archive
Yayıncı:
Internet Archive
Yazar(lar) :
Journal of Biomedical Research & Environmental Sciences
Yıl :
2020
Covid-19 Pandemic-Insights and Challenges Coronavirus Disease ( COVID- 19) is associated with respiratory illness that lead to severe pneumonia and Acute Respiratory Distress Syndrome (ARDS). Although related to the Severe Acute Respiratory Syndrome (SARS) and the Middle East Respiratory Syndrome (MERS), Covid- 19 shows some unique pathogenetic On the basis of the phylogenetic relationship as well as genomic structures, the Covid- 19 belongs to genera Betacoronavirus.
Yayıncı Web Sitesi
Tam Metin
Kaydet
The 2019 Novel Coronavirus (2019-nCoV) outbreak affected a large number of deaths with millions of confirmed cases worldwide. Coronavirus Disease (COVID-19) is associated with respiratory illness that lead to severe pneumonia and Acute Respiratory Distress Syndrome (ARDS). Although related to the Severe Acute Respiratory Syndrome (SARS) and the Middle East Respiratory Syndrome (MERS), Covid-19 shows some unique pathogenetic, epidemiological and clinical features. On the basis of the phylogenetic relationship as well as genomic structures, the Covid-19 belongs to genera Betacoronavirus. Human Betacoronaviruses (SARS-CoV-2, SARS-CoV, and MERS-CoV) have shared similarities, yet differences also in their genomic and phenotypic level that influence the pathogenesis. To gain knowledge regarding the pathophysiology and virulence of the Covid-19 virus, it is absolutely necessary to understand its genetic makeup, transmission, virulence factors, risk factors, diagnosis, clinical presentations, outcome predictions, management of risk factors and ways to control the disease thus providing an insight to the current or future treatment and management protocols. To provide a review of the differences in pathogenesis, epidemiology and clinical features of Covid-19, its transmission and replication dynamics, genome organization, current clinical trials and vaccine development strategies, Immunoinformatics, diagnostics and ways to control the pandemic, inorder to raise an increasing awareness, both to the public and for scientific perspectives.
4
COVID-19: an updated review
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Infekciâ i Immunitet
Yazar(lar) :
F. A. Isihak , M. A. Hamad , N. G. Mustafa
Yıl :
2020
COVID-19: an updated review COVID- 19 is a zoonotic disease that showed higher levels of transmissibility in humans. So, all the world scientists today are in a race against time to find a vaccine or treatment to COVID- 19, which requires a deeper understanding. covid-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
COVID-19 is a zoonotic disease that showed higher levels of transmissibility in humans. Coronavirus has the largest recognized genome (28–33 kb) of a positive-sense single stranded RNA. The genome composed of 5′-end, the translationable mRNA sequences for the key proteins; replicase, spike, envelop membrane, and nucleocapsid and 3′-end (polyA tail). This highly contagious virus may impair the immune system in the early phase of the disease, hence the symptoms of the disease appear very rapidly. Importantly until now, there is no efficient strategy for containing the disease. So, all the world scientists today are in a race against time to find a vaccine or treatment to COVID-19, which requires a deeper understanding.
DOI : 10.15789/2220-7619-CAU-1443
Anahtar Kelimeler : covid-19, sars-cov-2, vaccination, virus structure, epidemiology, spikes
Cilt: 10
Sayı: 2
Sayfa: 247 - 258
Sınıflandırma :
5
Immunized camels and COVID-19
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Asian Pacific Journal of Tropical Medicine
Yazar(lar) :
Sidgi S Hasson , Ali A Al-Jabri
Yıl :
2020
Immunized camels and COVID-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
DOI : 10.4103/1995-7645.282561
ISSN: 2352-4146
Cilt: 13
Sayı: 6
Sayfa: 239 - 241
Sınıflandırma :
6
COVID‐19 diagnostic testing: Technology perspective
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Clinical and Translational Medicine
Yazar(lar) :
Meng Xu , Dan Wang , Hongye Wang , Xiaomei Zhang , Te Liang , Jiayu Dai , Meng Li , Jiahui Zhang , Kai Zhang , Danke Xu , Xiaobo Yu
Yıl :
2020
COVID‐19 diagnostic testing: Technology perspective Abstract The corona virus disease 2019 ( COVID‐ 19) is a highly contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV Controlling the spread of SARS‐CoV‐2 is therefore inherently dependent on identifying and isolating infected individuals, especially since COVID‐ 19 can Here, we provide a comprehensive review of the different primary technologies used to test for COVID‐ 19 infection, discuss the advantages and disadvantages COVID‐19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Abstract The corona virus disease 2019 (COVID‐19) is a highly contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). More than 18 million people were infected with a total of 0.7 million deaths in ∼188 countries. Controlling the spread of SARS‐CoV‐2 is therefore inherently dependent on identifying and isolating infected individuals, especially since COVID‐19 can result in little to no symptoms. Here, we provide a comprehensive review of the different primary technologies used to test for COVID‐19 infection, discuss the advantages and disadvantages of each technology, and highlight the studies that have employed them. We also describe technologies that have the potential to accelerate SARS‐CoV‐2 detection in the future, including digital PCR, CRISPR, and microarray. Finally, remaining challenges in COVID‐19 diagnostic testing are discussed, including (a) the lack of universal standards for diagnostic testing; (b) the identification of appropriate sample collection site(s); (c) the difficulty in performing large population screening; and (d) the limited understanding of SARS‐COV‐2 viral invasion, replication, and transmission.
DOI : 10.1002/ctm2.158
Anahtar Kelimeler : COVIDu201019, diagnostic test, nucleic acid, SARSu2010COVu20102, serum
ISSN: 2001-1326
Cilt: 10
Sayı: 4
Sınıflandırma :
7
Current Avenues for COVID-19 Serology
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Annals of the National Academy of Medical Sciences (India)
Yazar(lar) :
Saumya Srivastava , Vidhi Jain , Vijaya Lakshmi Nag , Sanjeev Misra , Kuldeep Singh
Yıl :
2020
Current Avenues for COVID-19 Serology Development of rapid, reliable, and easy diagnostic tests with high-throughput is the need of the hour for laboratories combating the COVID- 19 pandemic Timely diagnosis, effective treatment, and future prevention are key to management of COVID- 19. covid-19 serological tests
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Development of rapid, reliable, and easy diagnostic tests with high-throughput is the need of the hour for laboratories combating the COVID-19 pandemic. While real-time polymerase chain reaction (RT-PCR) is the gold standard for diagnosing active infections, it is expensive and time-consuming. Serological diagnostic assays with a premise to aid rapid contact tracing, immune status determination, and identification of potential convalescent plasma donors hold great promise. Timely diagnosis, effective treatment, and future prevention are key to management of COVID-19.
DOI : 10.1055/s-0040-1713709
Anahtar Kelimeler : rapid diagnostic tests, covid-19 serological tests, convalescent plasma, immune status, antibody test
Cilt: 56
Sayı: 02
Sayfa: 087 - 090
Sınıflandırma :
8
COVID-19 Therapeutic Options Under Investigation
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Frontiers in Pharmacology
Yazar(lar) :
Malak Kaddoura , Malak Kaddoura , Malak AlIbrahim , Malak AlIbrahim , Ghina Hijazi , Ghina Hijazi , Nadia Soudani , Nadia Soudani , Amani Audi , Amani Audi , Habib Alkalamouni , Habib Alkalamouni , Salame Haddad , Salame Haddad , Ali Eid , Hassan Zaraket , Hassan Zaraket
Yıl :
2020
COVID-19 Therapeutic Options Under Investigation Since its emergence in China in December 2019, COVID- 19 has quickly spread around the globe causing a pandemic. Two compounds, remdesivir, and dexamethasone have been so far shown to reduce COVID- 19–associated death. Here, we provide a review of the potential therapeutic agents being considered for the treatment and management of COVID- 19 patients. COVID-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Since its emergence in China in December 2019, COVID-19 has quickly spread around the globe causing a pandemic. Vaccination or the development of herd immunity seems the only way to slow down the spread of the virus; however, both are not achievable in the near future. Therefore, effective treatments to mitigate the burden of this pandemic and reduce mortality rates are urgently needed. Preclinical and clinical studies of potential antiviral and immunomodulatory compounds and molecules to identify safe and efficacious therapeutics for COVID-19 are ongoing. Two compounds, remdesivir, and dexamethasone have been so far shown to reduce COVID-19–associated death. Here, we provide a review of the potential therapeutic agents being considered for the treatment and management of COVID-19 patients.
DOI : 10.3389/fphar.2020.01196
Anahtar Kelimeler : SARS-CoV-2, COVID-19, antivirals, adjunctive therapy, therapeutics
ISSN: 1663-9812
Cilt: 11
Sınıflandırma :
9
COVID-19: Zoonotic aspects
Dergi Makalesi

Dergi Makalesi
Kaynak :
Science Direct
Dergi:
Travel Medicine and Infectious Disease
Yayıncı:
Elsevier
Yazar(lar) :
Tauseef Ahmad , Muhammad Khan
Yıl :
2020
COVID-19: Zoonotic aspects
Yayıncı Web Sitesi
Tam Metin
Kaydet
DOI : 10.1016/j.tmaid.2020.101607
ISSN: 1477-8939
Cilt: 36
Sayfa: 101607
Sınıflandırma :
10
COVID-19-associated invasive pulmonary aspergillosis
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Annals of Intensive Care
Yazar(lar) :
Lynn Rutsaert , Nicky Steinfort , Tine Van Hunsel , Peter Bomans , Reinout Naesens , Helena Mertes , Hilde Dits , Niels Van Regenmortel
Yıl :
2020
COVID-19-associated invasive pulmonary aspergillosis
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
DOI : 10.1186/s13613-020-00686-4
ISSN: 2110-5820
Cilt: 10
Sayı: 1
Sayfa: 1 - 4
Sınıflandırma :
11
COVID-19: molecular diagnostics overview
Derleme Makalesi

Derleme Makalesi
Open Access
Kaynak :
Springer Link
Dergi:
Journal of Molecular Medicine
Yayıncı:
Springer Link
Yazar(lar) :
Marlin Touma
Konu :
olecular Medicine, Human Genetics, Internal Medicine
Yıl :
2020
COVID-19: molecular diagnostics overview Being very contagious, the new virus led the era of “ COVID- 19” which is the acronym of “coronavirus disease 2019,” evoking an imminent threat to global a molecular overview on the SARS-CoV-2 virus and summarize tremendous efforts that have been made to develop a rapid confirmatory diagnostic test for COVID - 19. COVID-19
Yayıncı Web Sitesi
Tam Metin
Kaydet
The last day of 2019 delivered the first report to the World Health Organization (WHO) about a group of cases of pneumonia of unknown etiology in Wuhan, China. Subsequent investigations identified the new comer, a novel coronavirus related to severe acute respiratory syndrome coronavirus (SARS-CoV) and thus was termed as SARS-CoV-2. Being very contagious, the new virus led the era of “COVID-19” which is the acronym of “coronavirus disease 2019,” evoking an imminent threat to global health security with unprecedented devastating challenges to human kind. In this article, we provide a molecular overview on the SARS-CoV-2 virus and summarize tremendous efforts that have been made to develop a rapid confirmatory diagnostic test for COVID-19. The diagnostic performances of the available tests are analyzed based on the best current information from the early research.
DOI : 10.1007/s00109-020-01931-w
Anahtar Kelimeler : COVID-19, SARS-CoV-2, Coronavirus
ISSN: 1432-1440
Cilt: 98
Sayı: 7
Sayfa: 947-954
Sınıflandırma :
12
Can Human Transmit COVID-19 to Animal?
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Journal of Clinical and Experimental Investigations
Yazar(lar) :
Soraia El Baz , Boujamâa Imziln
Yıl :
2020
Can Human Transmit COVID-19 to Animal? Coronavirus ( COVID- 19) has infected more than three million people worldwide and it’s widely believed to have originated in horseshoe bats and passed to Other reported cases of cats in Belgium tested positive with COVID- 19. Also, a tiger tested positive for COVID- 19 after coming into contact with an asymptomatic caretaker. COVID-19
Yayıncı Web Sitesi
Tam Metin
Kaydet
Coronavirus (COVID-19) has infected more than three million people worldwide and it’s widely believed to have originated in horseshoe bats and passed to humans through other species on sale in a wildlife market in Wuhan. First human transmission to dogs has been detected in Hong Kong; which they have caught the novel coronavirus from owners. Other reported cases of cats in Belgium tested positive with COVID-19. Researchers reveal that cats are not only susceptible to contracting coronavirus but can transmit it on other cats as well. Also, a tiger tested positive for COVID-19 after coming into contact with an asymptomatic caretaker. In this report, we provide all cases registered over the world prompting to take a closer look at the human to pet transmission of the virus and to keep measures to prevent exposure. Also, increased transmission of COVID-19 from human to animal can affect the global health security owing to its ability to rapidly spread due to movement of animals. So, we should reevaluate the probability that this outbreak might also be caused by infected pets’ hosts. Particular attention must be also paid to the distribution and the evolution of the virus in animals to control the COVID-19 pandemic.
DOI : 10.5799/jcei/8262
Anahtar Kelimeler : coronavirus, COVID-19, human-animal transmission
Cilt: 11
Sayı: 3
Sayfa:
Sınıflandırma :
13
A comprehensive review of COVID-19 characteristics
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Biological Procedures Online
Yazar(lar) :
Hanie Esakandari , Mohsen Nabi-Afjadi , Javad Fakkari-Afjadi , Navid Farahmandian , Seyed-Mohsen Miresmaeili , Elham Bahreini
Yıl :
2020
A comprehensive review of COVID-19 characteristics The epidemic disease caused by SARS-CoV-2 called coronavirus disease- 19 ( COVID- 19). The presence of COVID- 19 was manifested by several symptoms, ranging from asymptomatic/mild symptoms to severe illness and death. However, due to the worldwide spread of the virus, COVID- 19 has become a serious concern in the medical community. COVID-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Abstract In December 2019, a novel coronavirus, named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or (2019-nCoV) with unknown origin spread in Hubei province of China. The epidemic disease caused by SARS-CoV-2 called coronavirus disease-19 (COVID-19). The presence of COVID-19 was manifested by several symptoms, ranging from asymptomatic/mild symptoms to severe illness and death. The viral infection expanded internationally and WHO announced a Public Health Emergency of International Concern. To quickly diagnose and control such a highly infectious disease, suspicious individuals were isolated and diagnostic/treatment procedures were developed through patients’ epidemiological and clinical data. Early in the COVID-19 outbreak, WHO invited hundreds of researchers from around the world to develop a rapid quality diagnosis, treatment and vaccines, but so far no specific antiviral treatment or vaccine has been approved by the FDA. At present, COVID-19 is managed by available antiviral drugs to improve the symptoms, and in severe cases, supportive care including oxygen and mechanical ventilation is used for infected patients. However, due to the worldwide spread of the virus, COVID-19 has become a serious concern in the medical community. According to the current data of WHO, the number of infected and dead cases has increased to 8,708,008 and 461,715, respectively (Dec 2019 –June 2020). Given the high mortality rate and economic damage to various communities to date, great efforts must be made to produce successful drugs and vaccines against 2019-nCoV infection. For this reason, first of all, the characteristics of the virus, its pathogenicity, and its infectious pathways must be well known. Thus, the main purpose of this review is to provide an overview of this epidemic disease based on the current evidence.
DOI : 10.1186/s12575-020-00128-2
Anahtar Kelimeler : Coronavirus, COVID-19, SARS-CoV-2, 2019-nCoV, Viruses, Epidemic disease
ISSN: 1480-9222
Cilt: 22
Sayı: 1
Sayfa: 1 - 10
Sınıflandırma :
14
COVID-19: Mechanisms of Vaccination and Immunity
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Vaccines
Yazar(lar) :
Daniel E. Speiser , Martin F. Bachmann
Yıl :
2020
COVID-19: Mechanisms of Vaccination and Immunity Vaccines are needed to protect from SARS-CoV-2, the virus causing COVID- 19. COVID-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Vaccines are needed to protect from SARS-CoV-2, the virus causing COVID-19. Vaccines that induce large quantities of high affinity virus-neutralizing antibodies may optimally prevent infection and avoid unfavorable effects. Vaccination trials require precise clinical management, complemented with detailed evaluation of safety and immune responses. Here, we review the pros and cons of available vaccine platforms and options to accelerate vaccine development towards the safe immunization of the world’s population against SARS-CoV-2. Favorable vaccines, used in well-designed vaccination strategies, may be critical for limiting harm and promoting trust and a long-term return to normal public life and economy.
DOI : 10.3390/vaccines8030404
Anahtar Kelimeler : SARS-CoV-2, COVID-19, nucleic acid tests, serology, vaccination, immunity
ISSN: 2076-393X
Cilt: 8
Sayı: 404
Sayfa: 404
Sınıflandırma :
15
COVID-19: An International Public Health Concern
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Central Asian Journal of Global Health
Yazar(lar) :
Israel Oluwasegun Ayenigbara
Yıl :
2020
COVID-19: An International Public Health Concern This review presents a synopsis on the current COVID- 19 pandemic, with focus on preventive measures. Importantly, the new COVID- 19 belongs to the group of SARS-CoV, and it originated in bats but infected humans through smuggled pangolins. Furthermore, health care workers should adhere strictly to the standard preventive measures in areas of heightened COVID- 19 epidemic. covid-19 infection
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
This review presents a synopsis on the current COVID-19 pandemic, with focus on preventive measures. COVID-19 is a new viral infection, and is in form of a positive-sense, single-stranded RNA Coronavirus which belongs to an expanded group of viruses which were identified six decades ago. Importantly, the new COVID-19 belongs to the group of SARS-CoV, and it originated in bats but infected humans through smuggled pangolins. At first, the mode of transmission of infection was animal-to-person, but person-to-person and community transmission of the virus has been confirmed in many parts of the world. With an incubation period of between two-fourteen days, signs and symptoms of infection are mild to high respiratory illness; characterized with cough, breathing problems (shortness of breath), high temperature (Fever), tiredness (Fatigue) and nausea. Presently, no vaccines or specific treatment is available for COVID-19, in light of the aforementioned; prevention is the only substantial and less expensive option. With the envisaged explosive community transmission of COVID-19 in the coming weeks in places with limited daily testing, especially in African countries, it is recommended among many that social distancing which includes avoiding any form of contact with people; either through greetings, hugging or shaking of hands and large gatherings, avoid contact with animal items, dead or alive animals, sick and dead people from areas experiencing COVID-19 epidemic, and basic hygienic practices like thorough washing of hands with clean water and antiseptic soap for the duration of at least twenty seconds should be practiced always. However, in the absence of the aforementioned, an alcohol-based hand gel should be used on the hands frequently. Furthermore, health care workers should adhere strictly to the standard preventive measures in areas of heightened COVID-19 epidemic.
DOI : 10.5195/cajgh.2020.466
Anahtar Kelimeler : covid-19 infection, reservoir of infection, mode of transmission, signs and symptoms, preventive measures
ISSN: 2166-7403
Cilt: 9
Sayı: 1
Sınıflandırma :
16
COVID-19: animals, veterinary and zoonotic links
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Veterinary Quarterly
Yazar(lar) :
Ruchi Tiwari , Kuldeep Dhama , Khan Sharun , Mohd. Iqbal Yatoo , Yashpal Singh Malik , Rajendra Singh , Izabela Michalak , Ranjit Sah , D. Katterine Bonilla-Aldana , Alfonso J Rodriguez-Morales
Yıl :
2020
COVID-19: animals, veterinary and zoonotic links Coronavirus disease 2019 ( COVID- 19), has spread over 210 countries and territories beyond China shortly. The COVID- 19 outbreak once again proves the potential of the animal-human interface to act as the primary source of emerging zoonotic diseases. This review discusses in brief about the COVID- 19/SARS-CoV-2 with a particular focus on the role of animals, the veterinary and associated zoonotic links covid-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Coronavirus disease 2019 (COVID-19), has spread over 210 countries and territories beyond China shortly. On February 29, 2020, the World Health Organization (WHO) denoted it in a high-risk category, and on March 11, 2020, this virus was designated pandemic, after its declaration being a Public Health International Emergency on January 30, 2020. World over high efforts are being made to counter and contain this virus. The COVID-19 outbreak once again proves the potential of the animal-human interface to act as the primary source of emerging zoonotic diseases. Even though the circumstantial evidence suggests the possibility of an initial zoonotic emergence, it is too early to confirm the role of intermediate hosts such as snakes, pangolins, turtles, and other wild animals in the origin of SARS-CoV-2, in addition to bats, the natural hosts of multiple coronaviruses such as SARS-CoV and MERS-CoV. The lessons learned from past episodes of MERS-CoV and SARS-CoV are being exploited to retort this virus. Best efforts are being taken up by worldwide nations to implement effective diagnosis, strict vigilance, heightened surveillance, and monitoring, along with adopting appropriate preventive and control strategies. Identifying the possible zoonotic emergence and the exact mechanism responsible for its initial transmission will help us to design and implement appropriate preventive barriers against the further transmission of SARS-CoV-2. This review discusses in brief about the COVID-19/SARS-CoV-2 with a particular focus on the role of animals, the veterinary and associated zoonotic links along with prevention and control strategies based on One-health approaches.
DOI : 10.1080/01652176.2020.1766725
Anahtar Kelimeler : covid-19, sars-cov-2, animals, veterinary, zoonosis, transmission, one health
Cilt: 40
Sayı: 1
Sayfa: 169 - 182
Sınıflandırma :
17
COVID-19: the gut to lung hypothesis
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Global Biosecurity
Yazar(lar) :
Natalia Skorzewska
Yıl :
2020
COVID-19: the gut to lung hypothesis Increasingly COVID- 19 is being recognised as a multisystem disease, with viral replication within the gastrointestinal tract now being well accepted. covid-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Increasingly COVID-19 is being recognised as a multisystem disease, with viral replication within the gastrointestinal tract now being well accepted. This article collates evidence pointing to possible gastrointestinal transmission as well as outlining possible mechanisms for intra-institutional or cruise ship spread, and explores the possible impact of gastrointestinal replication on disease course.
DOI : 10.31646/gbio.68
Anahtar Kelimeler : covid-19, transmission, fecal aerosols
ISSN: 2652-0036
Cilt: 1
Sayı: 4
Sınıflandırma :
18
COVID-19: Modeling, Prediction, and Control
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
MDPI
Dergi:
Applied Sciences
Yayıncı:
MDPI AG
Yazar(lar) :
Ahmad Bani Younes , Zeaid Hasan
Yıl :
2020
COVID-19: Modeling, Prediction, and Control The newly emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as COVID- 19, has been recognized as a pandemic by the World aims to provide predictions of its spread using a stochastic Lotka–Volterra model coupled with an extended Kalman Filter (EKF) algorithm to model the COVID - 19 dynamics.
Yayıncı Web Sitesi
Tam Metin
Kaydet
The newly emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as COVID-19, has been recognized as a pandemic by the World Health Organization (WHO) on 11th March 2020. There are many unknowns about this virus to date and no vaccine or conclusive treatment due to the lack of understanding of its pathogenesis and proliferation pathways which are unknown and cannot be traced. The prime objective is to stop its spread worldwide. This article aims to provide predictions of its spread using a stochastic Lotka–Volterra model coupled with an extended Kalman Filter (EKF) algorithm to model the COVID-19 dynamics. Our results show the feasibility of utilizing this model for predicting the spread of the virus and the ability of different control measures (e.g., social distancing) on reducing the number of affected people.
DOI : 10.3390/app10113666
ISSN: 2076-3417
Sayı: 11
Cilt: 10
Sayfa: 3666
Sınıflandırma :
19
COVID-19 in Latin America
Dergi Makalesi

Dergi Makalesi
Kaynak :
Science Direct
Dergi:
The Lancet Infectious Diseases
Yayıncı:
Elsevier
Yazar(lar) :
Talha Burki
Yıl :
2020
COVID-19 in Latin America
Yayıncı Web Sitesi
Tam Metin
Kaydet
DOI : 10.1016/s1473-3099(20)30303-0
ISSN: 1473-3099
Sayı: 5
Cilt: 20
Sayfa: 547-548
Sınıflandırma :
20
Asymptomatic and Pre-Symptomatic COVID-19 in China
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Infectious Diseases of Poverty
Yazar(lar) :
Zunyou Wu , Jennifer M. McGoogan
Yıl :
2020
Asymptomatic and Pre-Symptomatic COVID-19 in China
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
DOI : 10.1186/s40249-020-00679-2
Anahtar Kelimeler : Novel coronavirus disease 2019, Asymptomatic, Pre-symptomatic, Transmission
Cilt: 9
Sayı: 1
Sayfa: 1 - 2
Sınıflandırma :
21
Superspreaders and the spread pattern of COVID-19
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
International Journal of Infectious Diseases
Yazar(lar) :
Gal Almogy , PhD
Yıl :
2020
Superspreaders and the spread pattern of COVID-19
Yayıncı Web Sitesi
Kaydet
22
COVID-19 and the uniqueness of South Africa
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Southern African Journal of Infectious Diseases
Yazar(lar) :
Jarrod Zamparini , Jacqui Venturas , Nina Diana
Yıl :
2020
COVID-19 and the uniqueness of South Africa covid-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
No abstract available.
DOI : 10.4102/sajid.v35i1.208
Anahtar Kelimeler : covid-19, south africa, severe acute respiratory syndrome, coronavirus, severe disease
Cilt: 35
Sayı: 1
Sayfa: e1 - e2
Sınıflandırma :
23
An overview on COVID-19: reality and expectation
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Bulletin of the National Research Centre
Yazar(lar) :
Manal A. Hamed
Yıl :
2020
An overview on COVID-19: reality and expectation By the declaration of WHO, COVID- 19 outbreak considered as a public health problem of international concern. The aim of this study is to provide a comprehensive view on COVID- 19 and the future expectations to control virus progression. Patients with liver disease, diabetes, high blood pressure, and obesity are more susceptible to the incidence of COVID- 19 infection. COVID-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Abstract Recently, severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), commonly known as coronavirus disease-2019 (COVID-19) has rapidly spread across China and around the world. By the declaration of WHO, COVID-19 outbreak considered as a public health problem of international concern. The aim of this study is to provide a comprehensive view on COVID-19 and the future expectations to control virus progression. Patients with liver disease, diabetes, high blood pressure, and obesity are more susceptible to the incidence of COVID-19 infection. So, there is a rapid need for disease diagnosis, vaccine development, and drug discovery to detect, prevent, and treat this sudden and lethal virus. Real-time polymerase chain reaction (RT-PCR) is considered as a rapid, accurate, and specific tool for disease diagnosis. Under this emergency situation that the world facing against COVID-19, there are about 15 potential vaccine candidates tested globally based on messenger RNA, DNA-based, nanoparticle, synthetic, and modified virus-like particle. Certain drugs that are clinically approved for other diseases were tested against COVID-19 as chloroquine, hydroxychloroquine, ivermectin, favipiravir, ribavirin, and remdesivir. Convalescent plasma transfusion and traditional herbal medicine were also taken into consideration. Due to the absence of effective treatment or vaccines against COVID-19 so far, the precautionary measures according to WHO’s strategic objectives are the only way to confront this crisis. Governments should adopt national medical care programs to reduce the risk of exposure to any future viral outbreaks especially to patients with pre-existing medical conditions.
DOI : 10.1186/s42269-020-00341-9
Anahtar Kelimeler : SARS-COV-2, COVID-19, Drugs, Vaccines, Plasma transfusion, Herbal treatment
ISSN: 2522-8307
Cilt: 44
Sayı: 1
Sayfa: 1 - 10
Sınıflandırma :
24
COVID-19 vaccine development and the way forward
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Indian Journal of Public Health
Yazar(lar) :
Narendra Kumar Arora , Manoja Kumar Das
Yıl :
2020
COVID-19 vaccine development and the way forward The whole globe is reeling under the COVID- 19 pandemic now. covid-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
The whole globe is reeling under the COVID-19 pandemic now. With the scale and severity of infection, number of deaths and lack of any definite therapeutic armamentarium, the vaccine development has been accelerated at a never-before pace. A wide variety of vaccine technologies and platforms are being attempted. Out of the over 108 efforts, 100 are in preclinical and eight in Phase 1 or 2 trial stage. While the availability of newer technologies has facilitated development, there are several challenges on the way including limited understanding of the pathophysiology, targeting humoral or mucosal immunity, lack of suitable animal model, poor success of human severe acute respiratory syndrome/Middle East Respiratory Syndrome vaccines, limited efficacy of influenza vaccines, and immune exaggeration with animal coronavirus vaccines. With the current scenario with political, funding, research, and regulatory supports, if everything sails through smoothly, the successful vaccine is expected in 12–18 months. Modestly efficacious vaccine may be also a good achievement.
DOI : 10.4103/ijph.IJPH_520_20
Anahtar Kelimeler : coronavirus, covid-19, severe acute respiratory syndrome-cov-2, technologies, vaccines development
Cilt: 64
Sayı: 6
Sayfa: 108 - 111
Sınıflandırma :
25
COVID-19 Evolution and Alternative Medicine - A Review
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Journal of Pure and Applied Microbiology
Yazar(lar) :
Shubhangi Goel , Anjana Goel
Yıl :
2020
COVID-19 Evolution and Alternative Medicine - A Review The current global health emergency, COVID- 19, is not the first time that coronaviruses have posed a threat to human world shrinking our numbers by thousands One such example is of curcumin, a secondary metabolite of turmeric, which is found to be effective against COVID- 19 protease by molecular docking analysis
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
The current global health emergency, COVID-19, is not the first time that coronaviruses have posed a threat to human world shrinking our numbers by thousands. Before this SARS-CoV in 2003 and MERSCoV in 2013 have caused epidemics. Four months in existence, and it has already affected 1,995,983 people and taken over 131,037 lives worldwide, yet we do not have any specific treatment available with us and the management is purely empirical. Looking at the similarities between SARS-CoV and SARS-CoV-2 in origin, genomics, pathogenesis and epidemiology, we can bring the researches done for SARS-CoV in use which can be our guide in finding an effective management strategy against SARSCoV-2. There are various researches and studies reporting the use and effect of various phytochemical compounds in SARS-CoV treatment. Already, the thought has been put into action and in-silico screening for various natural plant compounds have been done to find a potential candidate compound. One such example is of curcumin, a secondary metabolite of turmeric, which is found to be effective against COVID-19 protease by molecular docking analysis.
DOI : 10.22207/JPAM.14.SPL1.21
Anahtar Kelimeler : coronavirus, sars-cov, herbal medicine, complementary medicine
Cilt: 14
Sayı: suppl 1
Sayfa: 841 - 848
Sınıflandırma :
26
Successful containment of COVID-19: the WHO-Report on the COVID-19 outbreak in China
Başyazılar

Başyazılar
Open Access
Kaynak :
Springer Link
Dergi:
Infection
Yayıncı:
Springer Link
Yazar(lar) :
Bernd Salzberger , Thomas Glück , Boris Ehrenstein
Konu :
nfectious Diseases, General Practice, Internal Medicine
Yıl :
2020
Successful containment of COVID-19: the WHO-Report on the COVID-19 outbreak in China
Yayıncı Web Sitesi
Tam Metin
Kaydet
DOI : 10.1007/s15010-020-01409-4
ISSN: 1439-0973
Cilt: 48
Sayı: 2
Sayfa: 151-153
Sınıflandırma :
27
Cell-Mediated Immune Responses to COVID-19 Infection
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Frontiers in Immunology
Yazar(lar) :
Amélie Guihot , Amélie Guihot , Elena Litvinova , Brigitte Autran , Patrice Debré , Patrice Debré , Vincent Vieillard
Yıl :
2020
Cell-Mediated Immune Responses to COVID-19 Infection An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID- 19 by the World Health Organization, emerged in Wuhan Despite rigorous containment and quarantine efforts, the incidence of COVID- 19 continues to expand, causing explosive outbreaks in more than 160 countries This mini-review focuses on the cellular immune response to COVID- 19 in human subjects, compared to other clinically relevant coronaviruses to evaluate COVID-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City (China) in December 2019. Despite rigorous containment and quarantine efforts, the incidence of COVID-19 continues to expand, causing explosive outbreaks in more than 160 countries with waves of morbidity and fatality, leading to significant public health problems. In the past 20 years, two additional epidemics caused by CoVs have occurred: severe acute respiratory syndrome-CoV, which has caused a large-scale epidemic in China and 24 other countries; and respiratory syndrome-CoV of the Middle East in Saudi Arabia, which continues to cause sporadic cases. All of these viruses affect the lower respiratory tract and manifest as pneumonia in humans, but the novel SARS-Cov-2 appears to be more contagious and has spread more rapidly worldwide. This mini-review focuses on the cellular immune response to COVID-19 in human subjects, compared to other clinically relevant coronaviruses to evaluate its role in the control of infection and pathogenesis and accelerate the development of a preventive vaccine or immune therapies.
DOI : 10.3389/fimmu.2020.01662
Anahtar Kelimeler : SARS - CoV-2, COVID-19, innate immunity, adaptive immunity, coronavirus
ISSN: 1664-3224
Cilt: 11
Sınıflandırma :
28
Potential treatments for COVID-19; a literature review
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Archives of Academic Emergency Medicine
Yazar(lar) :
Ali Rismanbaf
Yıl :
2020
Potential treatments for COVID-19; a literature review SARS-CoV-2 is a newly emerging human infectious coronavirus that causes COVID- 19, which has been recognized as a pandemic by the World Health Organization Therefore, in this article, new potential COVID- 19 therapies are briefly reviewed.
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
SARS-CoV-2 is a newly emerging human infectious coronavirus that causes COVID-19, which has been recognized as a pandemic by the World Health Organization (WHO) on March 11th. There is still no vaccine or definitive treatment for this virus because its pathogenesis and proliferation pathways are still unknown. Therefore, in this article, new potential COVID-19 therapies are briefly reviewed.
DOI : 10.22037/aaem.v8i1.596
Anahtar Kelimeler : Coronavirus, Drug therapy, Clinical trial, Case reports, Review literature
ISSN: 2645-4904
Cilt: 8
Sayı: 1
Sınıflandırma :
29
Use Of Succulent Bio Medicines To Control COVID 19
e-Kitap

e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Internet Archive
Yayıncı:
Internet Archive
Yazar(lar) :
Dr Shibabrata Pattanayak
Yıl :
2020
Use Of Succulent Bio Medicines To Control COVID 19 some digestible capsular materials of biological origin without addition of any synthetic chemical and may be used as preventive oral medicines against COVID - 19.
Yayıncı Web Sitesi
Tam Metin
Kaydet
Use of succulent bio-medicines and other succulent bio-healthcare products can bring a dramatic change in initiation, progression as well as expression of symptoms of various diseases among individuals. Succulent parts of some effective medicinal plants in the form of paste or pressure extract can be covered by some digestible capsular materials of biological origin without addition of any synthetic chemical and may be used as preventive oral medicines against COVID-19. Plants having ethnomedicinal reports of having strong immunomodulation and antioxidation activities and plants having role in protection of respiratory organs may be selected for such use to strengthen the immunity power of the people to become refractory to the viral infections. Name of such medicinal plants with relevant parts and previous reports on their related activities, discussion of various steps related with preparation of a design for efficacy based study on the medicines and their dose determination; production, marketing and transport of these medicines up to the patient level; searching of answer of the questions raised against such herbal medicines and discussion of pros and cons of the use of such medicines are added in this book. A brief analysis of possible mechanism of actions of the succulent bio-medicines is also included in this book. [ISBN: 978-93-5407-265-9]
30
Mechanisms Underlying Potential Therapeutic Approaches for COVID-19
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Frontiers in Immunology
Yazar(lar) :
Abdelouaheb Benani , Sanae Ben Mkaddem , Sanae Ben Mkaddem
Yıl :
2020
Mechanisms Underlying Potential Therapeutic Approaches for COVID-19 Coronavirus disease ( COVID- 19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is a betacoronavirus, and is associated To prevent and stop the COVID- 19 pandemic, several clinical trials are in the pipeline. The current clinical trials either target the intracellular replication and spread of the virus or the cytokine storm inflammation seen in COVID- 19 cases COVID-19
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet
Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is a betacoronavirus, and is associated with cytokine storm inflammation and lung injury, leading to respiratory distress. The transmission of the virus is mediated by human contact. To control and prevent the spread of this virus, the majority of people worldwide are facing quarantine; patients are being subjected to non-specific treatments under isolation. To prevent and stop the COVID-19 pandemic, several clinical trials are in the pipeline. The current clinical trials either target the intracellular replication and spread of the virus or the cytokine storm inflammation seen in COVID-19 cases during the later stages of the disease. Since both targeting strategies are different, the window drug administration plays a crucial role in the efficacy of the treatment. Here, we review the mechanism underlying SARS-CoV-2 cell infection and potential future therapeutic approaches.
DOI : 10.3389/fimmu.2020.01841
Anahtar Kelimeler : SARS-CoV-2, COVID-19, immune therapy, monoclonal antibody, respiratory distress, cytokine treatment
ISSN: 1664-3224
Cilt: 11
Sınıflandırma :

Yayın Yılı

Sınırla

Doküman Türü
Tümü

Veri Tabanı
Tümü

Dergi İsmi
Tümü

Disiplin
Tümü

Disipline Göre İlgililik

Alt Disiplin
Tümü

Konu
Tümü

Yayıncı
Tümü

Lisan
Tümü

X
Filtreler