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Long-term treatment with linezolid in a patient with osteomyelitis undergoing hemodialysis
Dergi Makalesi

Dergi Makalesi
Kaynak :
Taylor and Francis
Dergi:
Journal of Chemotherapy
Yayıncı:
Informa UK Limited
Yazar(lar) :
Núria Berenguer , Olivia Ferrández , Francesc Barbosa , Olatz Urbina , Merçè Espona , Santiago Grau
Yıl :
2012
Francesc Barbosa
Yayıncı Web Sitesi
Tam Metin
Kaydet Alıntıla
Anemia and/or thrombocytopenia are the most relevant adverse effects of linezolid treatment. We report the case of a patient under hemodialysis who developed osteomyelitis involving the amputation stump of the left limb due to a vancomycin-resistant and teicoplanin-resistant Enterococcus faecium successfully treated with linezolid for 6 months. Close monitorization of the patient probably contributed to maintenance of treatment with linezolid despite hematological alterations observed, which could be attributed to either the underlying patient’s clinical condition or antimicrobial treatment.
DOI : 10.1179/1973947812y.0000000014
Anahtar Kelimeler : Anemia, Hemodialysis, Linezolid, Thrombocytopenia
ISSN: 1120-009X
Sayı: 4
Cilt: 24
Sayfa: 226-228
2
Factores de riesgo relacionados con el desarrollo de peritonitis en pacientes de diálisis peritoneal (DP)
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Enfermería Nefrológica
Yazar(lar) :
Eva Barbero Narbona , Elisabeth Tejeda Araez , Ernestina Junyent Iglesias , Ali Berrada , Silvia Collado Nieto , Francesc Barbosa Puig
Yıl :
2014
Francesc Barbosa Puig
Yayıncı Web Sitesi
Kaydet Alıntıla
Cilt: 17
Sayı: suppl 1
Sayfa: 38 - 38
3
Protección de los profesionales sanitarios en nefrología ante la pandemia por COVID-19
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Nefrología
Yazar(lar) :
María Dolores Arenas , Judit Villar , Cristina González , Higinio Cao , Silvia Collado , Francesc Barbosa , Marta Crespo , Juan Pablo Horcajada , Julio Pascual
Yıl :
2020
Francesc Barbosa
Yayıncı Web Sitesi
Kaydet Alıntıla
Resumen: La epidemia de COVID-19 representa un riesgo especial para los pacientes renales por sus comorbilidades y edad avanzada, y por la realización del tratamiento de hemodiálisis en salas colectivas, pero también supone un riesgo para los profesionales responsables de su atención. El presente manuscrito recoge una propuesta de actuación para prevenir la infección entre los profesionales en los Servicios de Nefrología. Abstract: The COVID-19 epidemic represents a special risk for kidney patients due to their comorbidities and advanced age, and the need for hemodialysis treatment in group rooms. It also represents a risk for professionals responsible for their attention. This manuscript contains a proposal for action to prevent infection of professionals in the Nephrology Services, one of the most valuable assets at the present time.
Anahtar Kelimeler : Nephrology, SARS-CoV-2, COVID-19, Coronavirus, Health-care workers
ISSN: 0211-6995
Cilt: 40
Sayı: 4
Sayfa: 395 - 402
4
Effective removal of colistin methanesulphonate and formed colistin during intermittent haemodialysis in a patient infected by polymyxin-only-susceptiblePseudomonas aeruginosa
Dergi Makalesi

Dergi Makalesi
Kaynak :
Taylor and Francis
Dergi:
Journal of Chemotherapy
Yayıncı:
Informa UK Limited
Yazar(lar) :
Sonia Luque , Luisa Sorli , Jian Li , Silvia Collado , Francesc Barbosa , Nuria Berenguer , Juan Pablo Horcajada , Santiago Grau
Yıl :
2013
Francesc Barbosa
Yayıncı Web Sitesi
Tam Metin
Kaydet Alıntıla
Colistin use has reemerged for the treatment of infections caused by multidrug-resistant Gram-negative bacteria. However, the information on its pharmacokinetics is limited, especially in patients with end-stage renal disease, in which dosage adjustments are contradictory, and evidences the need to investigate the removal of colistin through renal replacement therapies like haemodialysis. This case study showed efficient removal of colistin methanesulphonate and formed colistin during intermittent haemodialysis in a patient infected by polymyxin-only-susceptible Pseudomonas aeruginosa. These results suggest the importance to monitor colistin plasma concentrations in these patients to minimize treatment failure due to suboptimal exposure to antibacterial colistin.
DOI : 10.1179/1973947813y.0000000104
Anahtar Kelimeler : Colistin, Haemodialysis, Renal insufficiency, Pharmacokinetics, Pseudomonas aeruginosa
ISSN: 1120-009X
Sayı: 2
Cilt: 26
Sayfa: 122-124
5
Clinical Profiles in Renal Patients with COVID-19
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak 1:
MDPI
Kaynak 2:
Directory of Open Access Journals (DOAJ)
Dergi:
Journal of Clinical Medicine
Yayıncı:
MDPI AG
Yazar(lar) :
María Dolores Arenas , Marta Crespo , María José Pérez-Sáez , Silvia Collado , Dolores Redondo-Pachón , Laura Llinàs-Mallol , María Milagro Montero , Judith Villar-García , Carlos Arias-Cabrales , Francesc Barbosa , Anna Buxeda , Carla Burballa , Laia Sans , Susana Vázquez , Anna Oliveras , Marisa Mir , Sara Outón , Isabel Galcerán , Eulalia Solá , Adriana Sierra , Clara Barrios , Eva Rodríguez , Higini Cao , Roberto Güerri-Fernández , Juan Pablo Horcajada , Julio Pascual
Yıl :
2020
Francesc Barbosa
Tam Metin
Kaydet Alıntıla
The COVID-19 pandemic has led to frequent referrals to the emergency department on suspicion of this infection in maintenance hemodialysis (MHD) and kidney transplant (KT) patients. We aimed to describe their clinical features comparing confirmed and suspected non-confirmed COVID-19 cases during the Spanish epidemic peak. Confirmed COVID-19 ((+)COVID-19) corresponds to patient with positive RT-PCR SARS-CoV-2 assay. Non-confirmed COVID-19 ((−)COVID-19) corresponds to patients with negative RT-PCR. COVID-19 was suspected in 61 patients (40/803 KT (4.9%), 21/220 MHD (9.5%)). Prevalence of (+)COVID-19 was 3.2% in KT and 3.6% in MHD patients. Thirty-four (26 KT and 8 MHD) were (+)COVID-19 and 27 (14 KT and 13 MHD) (−)COVID-19. In comparison with (−)COVID-19 patients, (+)COVID-19 showed higher frequency of typical viral symptoms (cough, dyspnea, asthenia and myalgias), pneumonia (88.2% vs. 14.3%) and LDH and CRP while lower phosphate levels, need of hospital admission (100% vs. 63%), use of non-invasive mechanical ventilation (36% vs. 11%) and mortality (38% vs. 0%) (p < 0.001). Time from symptoms onset to admission was longer in patients who finally died than in survivors (8.5 vs. 3.8, p = 0.007). In KT and MHD patients, (+)COVID-19 shows more clinical severity than suspected non-confirmed cases. Prompt RT-PCR is mandatory to confirm COVID-19 diagnosis.
DOI : 10.3390/jcm9082665
ISSN: 2077-0383
Sayı: 8
Cilt: 9
Sayfa: 2665
Sınıflandırma :
6
COVID‐19 in elderly kidney transplant recipients
Dergi Makalesi

Dergi Makalesi
Kaynak :
Wiley Online Library
Dergi:
American Journal of Transplantation
Yazar(lar) :
Marta Crespo , María J. Pérezu2010Sáez , Dolores Redondou2010Pachón , Laura Llinàsu2010Mallol , María M. Montero , Judith Villaru2010García , Carlos Ariasu2010Cabrales , Anna Buxeda , Carla Burballa , Susana Vázquez , Thais López , Fátima Moreno , Marisa Mir , Sara Outón , Adriana Sierra , Silvia Collado , Clara Barrios , Eva Rodríguez , Laia Sans , Francesc Barbosa , Higini Cao , María D. Arenas , Roberto Güerriu2010Fernández , Juan P. Horcajada , Julio Pascual
Konu :
Immunology and Allergy, Pharmacology (medical), Transplantation
Yıl :
2020
Francesc Barbosa
Yayıncı Web Sitesi
Tam Metin
Kaydet Alıntıla
The SARS‐Cov‐2 infection disease (COVID‐19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID‐19 in 16 of our 324 KT patients aged ≥65 years old (4.9%). Many of them had had contact with healthcare facilities in the month prior to infection. Median time of symptom onset to admission was 7 days. All presented with fever and all but one with pneumonia. Up to 33% showed renal graft dysfunction. At infection diagnosis, mTOR inhibitors or mycophenolate were withdrawn. Tacrolimus was withdrawn in 70%. The main treatment combination was hydroxychloroquine and azithromycin. A subset of patients was treated with anti‐retroviral and tocilizumab. Short‐term fatality rate was 50% at a median time since admission of 3 days. Those who died were more frequently obese, frail, and had underlying heart disease. Although a higher respiratory rate was observed at admission in nonsurvivors, symptoms at presentation were similar between both groups. Patients who died were more anemic, lymphopenic, and showed higher D‐dimer, C‐reactive protein, and IL‐6 at their first tests. COVID‐19 is frequent among the elderly KT population and associates a very early and high mortality rate.
DOI : 10.1111/ajt.16096
ISSN: 1600-6135
Sayı: 10
Cilt: 20
Sayfa: 2883-2889
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