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Synergistic effect of Cinnamomum zeylanicum and Murraya koenigii formulation for antiobesity and hypolipidemic activity on wistar albino rats
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Dergi Makalesi
Kaynak :
Springer Link
Dergi:
Advances in Traditional Medicine
Yazar(lar) :
Punet Kumar , Sangam Singh , Md Iftekhar Ahmad
Konu :
Complementary and alternative medicine
Yıl :
2020
Sangam Singh
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Our research work focussed on to evaluating the synergistic action of ethanolic extract and its formulations (F1 and F2) of Cinnamomum zeylanicum (ECZ) and Murraya koenigii (EMK) for antiobesity and anti-hyperlipidemic activity on the high-fat diet on wistar albino rats. In this research work, rats fed on high-fat diet produced hyperlipidemia (115.00 ± 1.36 mg/dL), which led to an gain in the body weight (215 g), the total cholesterol, triglycerides (166.0 ± 0.577 mg/dL), VLDL (33.20 ± 0.233 mg/dL), total bilirubin (3.280 ± 0.010 mg/dL) and subside the levels of HDL (41.0 ± 0.894 mg/dL) and also changes in albino rats body temperature. ECZ, EMK, and its formulation F1, F2 (200 mg/kg and 400 mg/kg) indicated less in comparison to the HFD induced rats group. The result of the study reflected that ECZ, EMK, and its formulation F1, F2 showed antiobesity and anti-hyperlipidemic action depending on the dose. It was concluded that the ethanolic extract of C. zeylanicum, M. koenigii and its formulation F1, F2 possess antiobesity and anti-hyperlipidemic activity. It is drawn to conclusions, alcoholic extract of C. zeylanicum and M. koenigii and its formulation F1 and F2 possess antiobesity and anti-hyperlipidemic activity.
DOI : 10.1007/s13596-020-00460-8
Anahtar Kelimeler : Cinnamomum zeylanicum, Murraya koenigii, Antiobesity activity, Antihyperlipidemic activity, Wistar albino rats, Synergistic activity
ISSN: 2662-4052 2662-4060
Sayı: 3
Cilt: 21
Sayfa: 553-563

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