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Mycobacterium tuberculosis Infection and the development of laryngeal stenosis in children — is there a relationship?
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
A. L. Salova , O. G. Chelnokova , L. I. Mozzhukhina , T. A. Kogut
Yıl :
2019
Detskie Infekcii (Moskva)
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The aim is to study the relationship of Mycobacterium tuberculosis infection and the development of laryngeal stenosis (croup) in children. 250 children with croup aged from 6 months to 8 years were examined.It was found that infection with Mycobacterium tuberculosis in children with laryngeal stenosis (croup) developed at the age of under 4 years. The first episode of croup coincided in 90% of cases with the early period of primary infection with Mycobacterium tuberculosis. A high proportion of close contact with adult tuberculosis patients reached 35% in patients with recurrent laryngeal stenosis (croup). The incidence of tuberculosis among children with repeated episodes of croup was 30%. Anti-TB therapy for latent tuberculosis infection or local forms of tuberculosis led to the cessation of repeated episodes of croup in 85% of cases. Infection with Mycobacterium tuberculosis and active tuberculosis infection is considered as one of the factors contributing to the recurrent course of laryngeal stenosis in children.
DOI : 10.22627/2072-8107-2019-18-3-57-60
Anahtar Kelimeler : laryngeal stenosis, croup, recurrent course, mycobacterium tuberculosis, risk factor
ISSN: 2072-8107
Cilt: 18
Sayı: 3
Sayfa: 57 - 60
Sınıflandırma :
2
THE RESULTS OF LONG-TERM STUDY OF HERPESVIRUS INFECTION AT THE DEPARTMENT OF INFECTIOUS DISEASES IN CHILDREN OF RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
O. V. Shamsheva , F. S. Kharlamova , N. Yu. Egorova , O. V. Molochkova , E. V. Novosad , E. V. Simonova , T. M. Lebedeva , N. A. Guseva
Yıl :
2017
Detskie Infekcii (Moskva)
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As a result of many years of research, the role of Herpesviridae IV, V and VI types in the structure of various pathologies in children (with infectious mononucleosis (MI), CNS damage, long-term subfebrile syndrome, vasculitis syndrome, hepatitis, etc.) has been proven. MI is a polyethological disease associated with the Epstein-Barr virus (EBV), cytomegalovirus (CMV) and human herpesvirus type 6 (HHV6), occurring in mono(58%) and mixed infections in various combinations of herpesviruses (42%). Clinical manifestations of MI are typical and do not depend on etiology. With CMV and HHV6 IM, the response to heterophilic antibodies is always negative. Markers of herpesvirus infections were detected in 87% of children observed with neurological pathology. Children with diagnoses such as convulsive syndrome, epilepsy, neuropathy need a comprehensive examination (ELISA, PCR, Indirect immunofluorescence reaction) to identify markers of active replication of herpes viruses, with an emphasis on the detection of HHV6. In 44% of cases, the role of active herpesvirus infection in the etiology of prolonged subfebrile fever in children was proven, with mixed forms (78%) prevailing over monoinfection (22%). To identify the active forms of herpesvirus infection, it is important to detect the markers of viral replication. For EBV, this is the DNA of the virus in the blood, a smear from the tonsils and saliva, antigens of the complete assembly of EBV in blood lymphocytes, antibodies to the capsid antigen (VCA) of IgM and IgG classes, and IgG to the early (EA) antigen. With CMV infection, complete virus assembly antigens (pp65 and pp72) in blood lymphocytes and/or DNA of the virus in the blood, virus DNA in saliva and urine, antibodies to the IgM class virus and high IgG class titer in the blood. With HHV6 infection, the DNA of the virus in the blood, a smear from tonsils and saliva, complete antigens of HHV6 in blood lymphocytes, specific IgM and/or IgG antibodies are 2—4 times higher than the diagnostic values.
DOI : 10.22627/2072-8107-2017-16-2-5-12
Anahtar Kelimeler : herpesvirus infections, active replication markers, infectious mononucleosis, long-term subfebrile syndrome, children
ISSN: 2072-8107
Cilt: 16
Sayı: 2
Sayfa: 5 - 12
Sınıflandırma :
Biyotıp %100
Viroloji %99
3
Immunorehabilitation Children with Impaired Health Status
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
O. V. Shamsheva , I. V. Poleskо
Yıl :
2016
Detskie Infekcii (Moskva)
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Polyoxidonium® — domestic drug with a broad spectrum of pharmacological action, which is unparalleled in the world. The drug is used as an immunomodulator, detoksikant, immunostimulatory and sustained release carrier of pharmacologically active compounds. Currently collected convincing evidence base safe and effective use Polyoxidonium for respiratory diseases with severe severity of symptoms, including in children with a poor premorbid background (often ill children, chronic lymph adenotonzillit pathology of allergic disease), are at risk of complicated infection (ARI suppurative complications in history), the formation of prevention programs and immunoreabilitatsionnyh children with recurrent respiratory infections.
DOI : 10.22627/2072-8107-2016-15-2-41-44
Anahtar Kelimeler : sickly children, immunorehabilitation, polyoxidonium
ISSN: 2072-8107
Cilt: 15
Sayı: 2
Sayfa: 41 - 44
Sınıflandırma :
4
The etiology and clinical manifestations of acute intestinal infections in children, according to the Moscow hospital for 2016—2018
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
O. B. Kovalev , O. V. Molochkova , K. S. Konyaev , E. Yu. Pylaeva , P. A. Anufrieva , V. V. Kurmanova , A. A. Korsunsky , O. A. Kashchenko , E. V. Galeeva , N. I. Krylatova
Yıl :
2019
Detskie Infekcii (Moskva)
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The aim of the study was to study the etiology and clinical manifestations of acute intestinal infections (AII) in children aged 1 month to 18 years old who were hospitalized in the infectious diseases ward of a Moscow city hospital in 2016—2018.A retrospective analysis of 9076 case histories was performed. Etiological interpretation was carried out using bacteriological examination of feces, latex agglutination reaction, immunochromatographic analysis, polymerase chain reaction (PCR), serological reactions (indirect hemagglutination test).The majority of children hospitalized with AII (62.2%) were 1—6 years of age. The etiology of AII was deciphered in 32% of cases. Acute intestinal infections of viral etiology prevail (64%), among them — rotavirus (73%), less often — norovirus (21%). AII of bacterial etiology accounted for only 14%, among them salmonellosis remains significant (5.6%), and in young children — staphylococcal infection (1.7%). There were also mixed infections (22%), mainly of viral and bacterial etiology. Noteworthy is the increase in the frequency of occurrence of bacterial AII in the winter season. The leading topical diagnosis in the vast majority of patients (85.1%) was gastroenteritis with the development of exsiccosis (77.6%).
DOI : 10.22627/2072-8107-2019-18-2-54-57
Anahtar Kelimeler : acute intestinal infections (aii), rotavirus, norovirus, salmonella, st. aureus, children, gastroenteritis
ISSN: 2072-8107
Cilt: 18
Sayı: 2
Sayfa: 54 - 57
Sınıflandırma :
Viroloji %58
5
ACUTE STENOSING LARYNGOTRACHEITIS IN RESPIRATORY VIRAL INFECTIONS IN CHILDREN IN THE CLINICS OF ST. PETERSBURG
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
V. F. Sukhovetskaya , L. V. Osidak , V. S. Afanasyeva , V. N. Timchenko , O. I. Afanasyeva , E. A. Dondurey , E. V. Obraztsova , T. A. Kaplina
Yıl :
2017
Detskie Infekcii (Moskva)
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Kaydet
A comparative analysis of the development of acute stenosing laryngotracheitis (LSLT) in respiratory viral monoinfections in 1050 children, hospitalized in St. Petersburg hospitals. It was established that the clinical manifestations, severity and outcome of OSLT in viral monoinfections depend highly on the etiologic factor, the patient's age and his premorbid background. More often, stenoses of the larynx are provoked by parainfluenza viruses (26,7%), the next most important are the PC virus (22,3%) and adenoviruses (18,8%), but during epidemics the number of lesions of the larynx sharply increases, with influenza viruses as the main pathogen, reaching up to 31,1%. Boys (71,2%) suffer from LSLT more often than girls (28,8%). Burdened premorbid background were 88,1% of children.
DOI : 10.22627/2072-8107-2017-16-3-19-23
Anahtar Kelimeler : acute stenosing laryngotracheitis, respiratory-viral monoinfection, вurdened premorbid background
ISSN: 2072-8107
Cilt: 16
Sayı: 3
Sayfa: 19 - 23
Sınıflandırma :
6
PROPHYLACTIC EFFICACY OF VACCINATION AGAINST PNEUMOCOCCAL INFECTION IN CHILDREN WITH CHRONIC ADENOTONSILLAR DISEASES
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
S. N. Beniova , S. V. Taranova , A. L. Sizonenko , S. V. Babko
Yıl :
2015
Detskie Infekcii (Moskva)
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The article presents the results of study of clinical and immunological effectiveness of the application of the vaccine «Pneumo-23» for children of 3—7 years old, suffering from chronic nasopharyngeal ring diseases of pneumococcal etiology. The authors revealed reduction of the frequency of cases of the main disease exacerbation and cases of ARI adjoining. Reduction of the main clinical symptoms of chronic adenoiditis and chronic tonsillitis was registered. Number of specific IgMand IgGAT to PS of the vaccine doubled reliably.
DOI : 10.22627/2072-8107-2014-13-1-32-34
Anahtar Kelimeler : pneumococcal infection, children, vaccination
ISSN: 2072-8107
Cilt: 13
Sayı: 1
Sayfa: 32 - 34
Sınıflandırma :
7
The Case of Tick-borne Spotted Fever in a Child Arriving from the Crimea
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
N. N. Zvereva , M. A. Saifullin , L. S. Karan , V. F. Larichev , A. M. Butenko , M. V. Bazarova , R. F. Saifullin , S. V. Smetanina
Yıl :
2018
Detskie Infekcii (Moskva)
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A case of Tick-borne spotted fever in a child after a visit to an endemic region, the Republic of Crimea, is described. The disease caused difficulty in terms of clinical diagnosis, which led to the delayed prescription of specific therapy with doxycycline. The diagnosis of Тick-borne spotted fever was made on the basis of detecting R. conorii DNA in a washout with primary affect. In the course of the disease, IgM class antibodies were detected during serological analysis of paired serum.
DOI : 10.22627/2072-8107-2018-17-4-69-72
Anahtar Kelimeler : tick-borne spotted fever, marseilles fever, rickettsias, diagnostics, fever, exanthema, primary affect, regional lymphadenitis, doxycycline, children
ISSN: 2072-8107
Cilt: 17
Sayı: 4
Sayfa: 69 - 72
Sınıflandırma :
8
MODERNIZATION OF MEDICAL EDUCATION BY INCORPORATING ELEMENTS OF CONSTRUCTIVE PEDAGOGY IN THE EDUCATIONAL PROCESS
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
M. G. Romantsov , O. V. Shamsheva , I. Y. Melnikova
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
The article describes modern methods of teaching needed to ensure and improve the learning process, while maintaining traditional ways of learning. Character-ized by control methods to ensure the educational process, argues conducting educational monitoring and presents a contemporary view of the problem of quality of education in high school, in terms of its reform intensification of training in high school are invited to spend, using the elements of the educational process of constructive pedagogy.
DOI : 10.22627/2072-8107-2015-14-1-55-59
Anahtar Kelimeler : intensification of the process of learning, constructive pedagogy, educational monitoring, quality of education
ISSN: 2072-8107
Cilt: 14
Sayı: 1
Sayfa: 55 - 59
Sınıflandırma :
Eğitim %100
9
CLINICAL CASE OF SKIN LESIONS WITH PARVOVIRUS B19 INFECTION
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
L. I. Ilienko , A. G. Pashinyan , V. Yu. Vasenova
Yıl :
2018
Detskie Infekcii (Moskva)
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Kaydet
Clinico-epidemiological characteristics of parvovirus В19 infection are presented. Especially dangerous is the virus for pregnant women in the first and second trimesters of pregnancy, as it can lead to spontaneous abortion, the development of non-immune dropsy or intrauterine fetal death. Infectious erythema is characterized by a bright erythema of the cheek skin — a symptom of «spanked» cheeks, a patchy-papular «lacy» rash on the skin of the trunk and extensor surfaces of the extremities, more common in children aged 4 to 10 years. Diagnosis of parvovirus infection B19 is based on the results of serological methods, PCR, detection of IgM, immunoblot IgM/IgG. A clinical case of infectious erythema in a girl of 5 years is described.
DOI : 10.22627/2072-8107-2018-17-3-68-71
Anahtar Kelimeler : infectious erythema, parvovirus b19
ISSN: 2072-8107
Cilt: 17
Sayı: 3
Sayfa: 68 - 71
Sınıflandırma :
Viroloji %96
10
Clinical Observation Current Varicella Encephalitis in Children
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
O. G. Kimirilova , G. A. Harchenko , A. A. Kimirilov
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
The article presents the clinical picture, the course and outcome of encephalitis caused by the varicella-zoster virus. It is shown that the inclusion in the complex therapy of abnormal nucleoside (Acyclovir and its derivatives), intravenous immunoglobulin, promotes the release of patients from critical conditions to reverse the development of the pathological process.
DOI : 10.22627/2072-8107-2015-14-4-67-69
Anahtar Kelimeler : varicella-zoster, encephalitis, clinic, treatment
ISSN: 2072-8107
Cilt: 14
Sayı: 4
Sayfa: 67 - 69
Sınıflandırma :
Biyotıp %100
Viroloji %89
11
LABORATORY DIAGNOSIS OF OPPORTUNISTIC INFECTIONS AT LONG-SUBFEBRILITES AND OBSTRUCTIVE BRONCHITIS IN CHILDREN WITH MIXED INFECTION
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
T. N. Rybalkina , N. V. Karazhas , M. U. Kalugina , M. N. Kornienko , V. F. Uchaykin , T. M. Lebedeva , N. U. Kan , L. V. Feklisova , M. K. Khadisova , A. M. Karamzin
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
The article discusses the role of agents of opportunistic infections (OI) in the etiology of children’s infectious diseases illustrated by the long-subfebrilites and obstructivebronchitis. When children without expressed immunity disorders are infected with mixed infections OI have more pronounced manifestations, which requires appropriate treatment. At the same time, the similarity of the clinical manifestations does not mean that an etiological diagnosis can be determined without laboratory diagnostic methods. The importance of routine pediatrics monitoring of children with latent forms of OI is emphasized.
DOI : 10.22627/2072-8107-2013-12-3-40-43
Anahtar Kelimeler : opportunistic infections, herpes virus infections, pneumocystosis, mycoplasmosis
ISSN: 2072-8107
Cilt: 12
Sayı: 3
Sayfa: 40 - 43
Sınıflandırma :
12
Respiratory syncytial viral infection in children. Role in the structure of respiratory pathology and clinical and immunological features
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
V. V. Sokolovskaya , A. I. Grekova
Yıl :
2020
Detskie Infekcii (Moskva)
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Kaydet
Acute respiratory infections (ARI) consistently occupy a leading place in the structure of infectious pathology, especially among children. The spectrum of pathogens is usually determined by the season and age aspect of the observed. In a large number of respiratory viruses, respiratory syncytial virus (RSV) occupies a special place due to the variety and severity of clinical manifestations of the disease caused by it in young children. This article is devoted to the analysis of the clinical course of RSV infection in children, the study of the features of the immune status against the background of this disease.It was found that in most cases of RSV infection in children was characterized by signs of bronchial obstruction syndrome and as a consequence in this group of children were found to have dysfunction of the immune system and reduction in the total number of T-lymphocytes, the hyperactivation In-cell component of adaptive immunity, manifested disimmunoglobulinemia (increase in the content of total IgE at lower IgA and IgG), that is, with the formation of immunodeficiency states from T- and B-cell links of adaptive immunity, with long-term recovery of impaired performance, even against the background of effective antiviral therapy.
DOI : 10.22627/2072-8107-2020-19-1-17-20
Anahtar Kelimeler : respiratory syncytial viral infection, morbidity, children, bronchoobstructive syndrome, immunity
ISSN: 2072-8107
Cilt: 19
Sayı: 1
Sayfa: 17 - 20
Sınıflandırma :
Viroloji %100
13
The efficiency of interferon therapy for acute respiratory viral infections in young children
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
T. K. Chudakova , E. V. Mikhaylova
Yıl :
2020
Detskie Infekcii (Moskva)
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Kaydet
The problem of choosing an effective etiotropic treatment for acute respiratory viral infections in young children is one of the urgent in pediatrics.Materials and methods. The article presents data on the mechanism of the combined antiviral and immunomodulating action of the drug recombinant interferon alpha-2b. The results of observation of 80 children aged 3 to 12 months with acute respiratory viral infections of various etiologies are presented. Results. Clinical and laboratory indicators of intoxication that occur during acute respiratory viral infections in children have been identified. It has been shown that the use of rectal suppositories of interferon alpha-2b in the treatment of young children with acute respiratory viral infections causes a rapid relief of the clinical symptoms of the disease and helps to reduce the duration of hospital treatment of patients.
DOI : 10.22627/2072-8107-2020-19-1-13-16
Anahtar Kelimeler : acute respiratory viral infections, children, antiviral therapy, interferon alfa-2b, viferon®
ISSN: 2072-8107
Cilt: 19
Sayı: 1
Sayfa: 13 - 16
Sınıflandırma :
Viroloji %90
14
FORMATION OF COMPETENCY-BASED MODEL IN PROFESSIONAL TRAINING OF MODERN DOCTOR
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
M. G. Romantsov , I. Yu. Melnikova , A. A. Shuldyakov , O. V. Shamsheva
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
The shift in priorities in the system of Russian education, transition from reproductive learning to learner-centered approach, incorporation of competency-based approach into the educational standards of «the third generation» require the training of a competitive specialist with professional competency. Types of competencies are characterized. The competency presenting certain requirements is studied. The mastering of the requirements will enable to train qualified specialists. The quality of education directly influences the level of professional activity through training of specialists and development of sciences. Competence-oriented approach and adherence to pedagogic requirements in education enables the efficacy of professional training. Innovative techniques and approaches to organizing educational process in their active form stimulate the process of studying.
DOI : 10.22627/2072-8107-2013-12-3-62-64
Anahtar Kelimeler : competence, competency, innovative methods of education, professional training, competitive specialist, modernization of education
ISSN: 2072-8107
Cilt: 12
Sayı: 3
Sayfa: 62 - 64
Sınıflandırma :
15
INFECTION OF HUMAN HERPES VIRUS TYPE 6 IN CHILDREN WITH PYELONEPHRITIS
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
Т. V. Barkhatova , N. E. Senyagina , V. V. Krasnov
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
The authors studied the incidence of detection of human herpes virus type 6 (HHV 6) infection markers in 207 children aged from 1 year to 7 years (126 children with acute pyelonephritis and 81 child in the control group with no signs of urinary tract infection). It was found out that of all the children studied ≥ 89,2% of the patients with acute pyelonephritis and ≥ 65,3% of the children without urinary tract infection are infected with HHV 6. The characteristic of HHV — 6 infection in children with acute pyelonephritis is the presence of active viral replication with the presence of HHV 6 DNA in the blood. This fact indicates the risk of repeated episodes of the disease and is the condition for administration of antiviral and / or immunotropic therapy. The authors proved low predictive value of HHV 6 DNA detection in urine of children with acute pyelonephritis.
DOI : 10.22627/2072-8107-2014-13-1-26-28
Anahtar Kelimeler : children, acute pyelonephritis, 6 hhv infection
ISSN: 2072-8107
Cilt: 13
Sayı: 1
Sayfa: 26 - 28
Sınıflandırma :
16
HEMATOLOGICAL PARAMETERS IN PREDICTING OF THE COURSE OF LYME BORRELIOSIS IN CHILDREN
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
A. P. Pomogaeva , O. V. Obidina , M. O. Karavaeva
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
The study involved 224 patients with Lyme borreliosis children with erythema (103) and without erythema (121 children) forms. The analysis of the clinical symptoms and hematological parameters in the course of the disease was prosecute. A comprehensive statistical analysis of the results allowed to highlight blood count (content stab and segmented neutrophils, erythrocyte sedimentation rate) and the number of symptoms at admission prognostic criteria of severity, chronicity of the Lyme borreliosis. This allows to make a correction in the treatment of patients with Lyme borreliosis.
DOI : 10.22627/2072-8107-2014-13-4-23-27
Anahtar Kelimeler : children, ixodes tick-borne lyme disease, hematologic parameters
ISSN: 2072-8107
Cilt: 13
Sayı: 4
Sayfa: 23 - 27
Sınıflandırma :
17
Secondary Hemophagocytic Syndrome Associated with Herpes Virus Infections
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
S. R. Rodionovskaya , I. B. Alakaeva , I. N. Tsymbal
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
Hemophagocytic syndrome is one of the complications of herpes virus infections. Here, we describe the case of a 8—year-old male with secondary hemophagocytic syndrome. The disease was diagnosed in the early stages. The patient received treatment with dexamethasone, intravenous immunoglobulin, which has led to a weakening of the ignition and the suppression of the disease with rapid treatment.
DOI : 10.22627/2072-8107-2015-14-4-64-67
Anahtar Kelimeler : hemophagocytic syndrome, epstein-barr virus, cytomegalovirus, infectious mononucleosis, children
ISSN: 2072-8107
Cilt: 14
Sayı: 4
Sayfa: 64 - 67
Sınıflandırma :
Hematoloji %100
18
The modern view of congenital cytomegalovirus infection: diagnosis, treatment and prevention
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
N. V. Kholodnova , L. N. Mazankova , A. A. Volter , I. E. Turina
Yıl :
2019
Detskie Infekcii (Moskva)
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Kaydet
A literature review of the works of foreign and domestic authors is devoted to modern approaches to the diagnosis, treatment and prevention of congenital cytomegalovirus infection (cCMV). The data of international consensuses are presented: «Congenital Cytomegalovirus: A European Expert Consensus Statement on Diagnosis and Management» adopted by the cCMV group from the European society for pediatric infectious diseases (ESPID) in Leipzig, Germany in 2015, and «Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy» by an informal International Congenital Cytomegalovirus Recommendations Group (ICCRG), established in Brisbane, Australia in 2015 as part of the 5th International cCMV Conference about evidence-based treatment cCMV using antiviral drugs and immunotherapy. Particular attention is paid to the prevention of cCMV in both pregnant and newborns, as well as data from international studies on the cytomegalovirus vaccination.
DOI : 10.22627/2072-8107-2019-18-4-56-63
Anahtar Kelimeler : newborn, cytomegalovirus infection, congenital infection
ISSN: 2072-8107
Cilt: 18
Sayı: 4
Sayfa: 56 - 63
Sınıflandırma :
19
Characteristics of Giardiasis and Enterobiаsis in children of Astrakhan region
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
R. S. Arakelyan , E. I. Okunskayu , N. A. Sergeeva , O. V. Konnova , Kh. M. Galimzyanov , G. L. Shendo , V. Sh. Sangadzhieva , P. K. Magomedova , A. N. Zagina
Yıl :
2019
Detskie Infekcii (Moskva)
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Purpose: assessment of the clinical and epidemiological situation of current invasions in children of the Astrakhan region. 315 outpatient cards of children were analyzed in 2016.The diagnosis of Giardiasis was made to 151 children, the diagnosis of Enterobiasis — 164. The age of all observed children ranged from 9 months to 17 years. The largest part was made up of children aged 3 to 14 years of age — 80.3%, among them enterobiasis was identified — in 46.7%, giardiasis — in 33.6% of cases. Most of the children — 90.5% were from organized groups (they attended preschool institutions or school). The reasons for the examination of all children were varied. Some children — 63.5% went to the doctor with complaints or clinical symptoms. Another part of the children — 33% of the diagnosis was made as a result of preventive examinations.In most cases — 78.7% various bad habits were identified. Thus, geophagy (the habit of eating the earth) was noted in 33.3% of children, and onigophagy (the habit of biting the nails) in 24.8%. In 21.3% of cases, bad habits were absent. Contact with pets was established in 22.9% of children. According to the ultrasound, most children with giardiasis (83.8%) had pathology (reactive changes of the pancreas, liver, gallbladder dyskinesia, etc.)In case of giardiasis niferator, albendazole was administered. In case of enterobiasis albendazole, pyrantel, and mebendazole were administered in age dosages. After antiparasitic treatment, in 91.4% of cases, the clinical symptoms of the disease completely disappeared, with giardiasis — in 85.4%, with enterobiasis — in 97% of cases.In 1.3% of children with giardiasis, after several courses of antiparasitic drugs, Giardia was found in feces in the absence of complaints and clinical symptoms, indicating a possible Giardia carrier parasite in children.
DOI : 10.22627/2072-8107-2019-18-2-49-53
Anahtar Kelimeler : enterobiаsis, giardiasis, parasitosis, giardia lamblia, enterobius vermicularis, children
ISSN: 2072-8107
Cilt: 18
Sayı: 2
Sayfa: 49 - 53
Sınıflandırma :
20
BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
A. G. Bokovoy , I. V. Kovalev , L. F. Makkaveeva , O. A. Volodina , A. A. Komarov , A. Yu. Medkova , N. B. Tanina
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
80 patients were observed with infectious mononucleosis (IM) from 2 to 12 years. Diagnosis was confirmed by the definition of M- and G-antibodies to EBV, CMV, HHV6, PCR DNA these viruses, bacteriological and blood-tests investigations. 40 patients was given bifidumbacterin forte 45—90 doses a day and cycloferon 8 mg/kg/weight a day(1-st group). The comparison group consisted of 40 patients with IM receiving symptomatic therapy and antibiotics (2-nd group). The observations shoved significant decreasing of length of clinical symptoms IM in the 1-st group with comparison of the 2-nd group. The obtained results allow to recommend bifidumbacterin forte and cycloferon in the complex therapy in children with infectious mononucleosis.
DOI : 10.22627/2072-8107-2015-14-1-3-8
Anahtar Kelimeler : infectious mononucleosis, bifidumbacterin forte, cycloferon, children
ISSN: 2072-8107
Cilt: 14
Sayı: 1
Sayfa: 30 - 35
Sınıflandırma :
21
СВЕДЕНИЯ ОБ ИНФЕКЦИОННЫХ И ПАРАЗИТАРНЫХ ЗАБОЛЕВАНИЯХ ЗА ЯНВАРЬ—ДЕКАБРЬ 2013 ГОДА. РОССИЙСКАЯ ФЕДЕРАЦИЯ
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
DOI : 10.22627/2072-8107-2014-13-1-5
ISSN: 2072-8107
Cilt: 13
Sayı: 1
22
POSTINFECTIOUS OBLITERANS BRONCHIOLITIS IN CHILDREN
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
E. V. Boitsova , D. Yu. Ovsyannikov
Yıl :
2015
Detskie Infekcii (Moskva)
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Literature review describes the problem of bronchiolitis obliterans in children. The review analyzes modern date on etiology, morphological sings, clinical course, treatment and prognosis of diseas. The modern capabilities of diagnosis based on chest X-ray, computed tomography and pulmonary function testing are discussed.
DOI : 10.22627/2072-8107-2014-13-2-24-28
Anahtar Kelimeler : postinfectious bronchiolitis obliterans, chronic bronchiolitis, respiratory infections, chronic obstructive lung diseases, children
ISSN: 2072-8107
Cilt: 13
Sayı: 2
Sayfa: 24 - 28
Sınıflandırma :
23
Каковы специфические профессиональные права врача?
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yıl :
2019
Detskie Infekcii (Moskva)
Yayıncı Web Sitesi
Kaydet
Научная рецензия на книгу А.А. Понкиной и И.В. Понкина «Права врачей» (второе издание, 2019 год, Москва, издательство ГЭОТАР-Медиа, 192 стр.)*
ISSN: 2072-8107
Cilt: 18
Sayı: 3
24
CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF SHIGELLOSIS ASSOCIATED WITH HERPESVIRUS INFECTIONS IN CHILDREN: A CLINIC, DIAGNOSIS AND TREATMENT
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
E. N. Simovanyan , V. B. Denisenko
Yıl :
2017
Detskie Infekcii (Moskva)
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The purpose is to characterize the features of the clinical picture, interferon and immune system status in shigellosis associated with herpesvirus infections in children, and to justify the inclusion of recombinant interferon-a2b (VIFERON®) in the complex treatment program of the disease. Clinical and immunological examination of 136 patients with shigellosis at the age from 1 to 3 years was carried out. In 65 children the active form of herpesvirus infection was diagnosed, in 20 patients it was absent. Active form of herpesvirus infection developed in children with a burdened premorbid background. These patients showed a violation of the immune response regulation by cellular type (reduction of interferon-g spontaneous and stimulated production, expression of CD119 receptors), the effector stage of the adaptive immune response. Clinically associated shigellosis was characterized by a severe course, a frequent development of complications. Inclusion of recombinant interferon-a2b (VIFERON®) in the complex program of treatment promoted the modulation of the regulatory and effector stages of the immune response. There was a reduction in the duration of the main symptoms of the disease and the stay of patients in the hospital.High efficiency of recombinant interferon-a2b (VIFERON®) application make it possible to recommend the inclusion of this drug in the treatment of shigellosis associated with herpesvirus infection in children.
DOI : 10.22627/2072-8107-2017-16-4-29-36
Anahtar Kelimeler : shigellosis, herpesvirus infection, children, recombinant interferon-2b
ISSN: 2072-8107
Cilt: 16
Sayı: 4
Sayfa: 29 - 36
Sınıflandırma :
Biyotıp %100
Viroloji %31
25
The clinical and epidemiological features of HHV-6A and HHV-6B infections in children of Moscow
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
M. Yu. Lysenkova , E. V. Melekhina , N. V. Karazhas , O. A. Svitich , P. A. Veselovsky , T. N. Rybalkina , R. E. Boshyan , V. V. Kosenchuk , A. D. Muzyka , A. V. Gorelov , D. V. Usenko , M. Yu. Ivanova
Yıl :
2019
Detskie Infekcii (Moskva)
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Kaydet
Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form of the developing pathology depends on the localization of the virus in T-lymphocytes and on virus type: HHV-6A or HHV-6B, but identification of the type is possible by nucleotide sequence only. In Russia, researching on the typing of HHV-6 are conducted in Moscow and St. Petersburg mainly, but results is discordant. Also the prevalence of HHV-6A and HHV-6B among various population groups is of particular interest.
DOI : 10.22627/2072-8107-2019-18-1-11-16
Anahtar Kelimeler : human herpesvirus type 6, hhv-6a, hhv-6b, typing
ISSN: 2072-8107
Cilt: 18
Sayı: 1
Sayfa: 11 - 16
Sınıflandırma :
Viroloji %92
26
THE SENSITIVITY OF NOSOCOMIAL STRAINS ACINETOBACTER SPP. TO SOME ANTIBIOTICS IN A MULTIDISCIPLINARY HOSPITAL IN BAKU CITY
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
S. A. Atakishizadeh
Yıl :
2018
Detskie Infekcii (Moskva)
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Kaydet
The sensitivity to some antibiotics of Acinetobacter spp., that cause pneumonia and septic infections in surgical clinic were studied. Acinetobacter spp. were isolated as dominant causative agent 14.6% from sputum of the patients with pneumonia and 13% from blood of the patients with septic infections.Acinetobacter spp. were highly resistant to some antibiotics. Most strains isolated from sputum were susceptibile to colistin and half of strains, isolated from blood to colistin and tigesikline.
DOI : 10.22627/2072-8107-2018-17-3-62-63
Anahtar Kelimeler : nosocomial infections (hospital-acuired infections), acinetobacter spp., sensitivity to antibiotics
ISSN: 2072-8107
Cilt: 17
Sayı: 3
Sayfa: 62 - 63
Sınıflandırma :
27
ARVI Problem in Pediatrics
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
V. F. Uchaykin
Yıl :
2016
Detskie Infekcii (Moskva)
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Kaydet
DOI : 10.22627/2072-8107-2012-11-0-3
ISSN: 2072-8107
Cilt: 11
28
RECURRENT RESPIRATORY INFECTIONS IN CHILDREN AND THE PROGRAM IMMUNOREHABILITATION
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
Т. A. Chebotareva , L. N. Mazankova , A. P. Hoperskova , V. V. Malinovskaya , V. D. Koltsov , G. S. Bragina
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
The paper proposed a modern rehabilitation program for children with recurrent infections of the respiratory tract. As a result, it is shown interferon and immunotherapy is an important component of an integrated approach to the rehabilitation of children with recurrent respiratory infections, positively influencing to the nature of the immunological abnormalities. Using this scheme can reduce the frequency of episodes of ARI and increase the duration of clinically successful period after the experimentation.
DOI : 10.22627/2072-8107-2014-13-3-61-64
Anahtar Kelimeler : children, recurrent infections, acute respiratory infections, immunity, interferons, viferon
ISSN: 2072-8107
Cilt: 13
Sayı: 3
Sayfa: 61 - 64
Sınıflandırma :
29
IMMUNOPATHOGENESIS OF ACUTE RESPIRATORY INFECTIONS AND TACTICS OF RATIONAL CHOICE OF ETIOTROPIC IMMUNOMODULATORY THERAPIES IN CHILDREN
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
V. V. Malinovskaya , V. P. Timina , L. N. Mazankova , T. A. Chebotareva
Yıl :
2015
Detskie Infekcii (Moskva)
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Kaydet
The article demonstrates that the basis for pathogenesis of acute respiratory infection (ARI ) is a deficiency in a number of factors of virus protection. This deficiency manifests itself through low concentration of interferon and secretory IgA in the nasal mucosa at higher levels of IL-8, alongside with low serum antiviral activity and significant inhibition of interferon production and reduction of the compensatory mechanisms of adaptive immunity. These disorders require prescription of alpha-interferon preparations. For infants and children with a burdened pre-morbid background, regardless of age, such preparations can be administered with all clinical forms of ARI; in older children — with severe forms, including complications. Alpha-interferon preparations can be introduced at in any stage of the disease. Combination therapy with alpha-interferon drugs (VIFERON® suppositories and VIFERON® ointment) allows for enhanced clinical and immunological effects of therapy.
DOI : 10.22627/2072-8107-2013-12-4-14-19
Anahtar Kelimeler : acute respiratory infection, pathogenesis, interferon, interferon-alpha drugs, viferon® suppositories, viferon® ointment
ISSN: 2072-8107
Cilt: 12
Sayı: 4
Sayfa: 14 - 19
Sınıflandırma :
30
INNOVATIONS IN THE MANAGEMENT OF CHILDREN’S NEUROINFECTIONS
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Detskie Infekcii (Moskva)
Yazar(lar) :
N. V. Skripchenko , Yu. V. Lobzin , V. B. Voytenkov , V. E. Karev , L. A. Alekseeva , Yu. P. Vasil'yeva , A. A. Vil'nits , A. V. Klimkin
Yıl :
2017
Detskie Infekcii (Moskva)
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Kaydet
The article describes some topical problems of neuroinfections in children and the ways of their solutions on the basis of the experience of a leading institution — Pediatric Research and Clinical Center for Infectious Diseases. There are introduced some innovation approaches of diagnostics and therapy of bacterial purulent meningitis tested at the institution. There are described diagnostic markers of meningitis in children, method of ultrasound evaluation monitoring of the condition of kidneys, renal blood flow, adrenal glands in the patients with a fulminant course of generalized form of meningococcal infection, and innovation therapeutic approach by recombinant interleukin-2 — roncoleukin introduction to the complex therapy. There is reflected an innovation method of differential diagnostics by the determination of acute-phase protein haptoglobin in cerebrospinal fluid. There are presented the tested methods to diagnose sensorineural deafness in children with bacterial purulent meningitis, critical condition polyneuropathy, and inflammatory polyneuropathy by the technique of rehabilitation potential evaluation.
DOI : 10.22627/2072-8107-2017-16-3-5-9
Anahtar Kelimeler : children, neuroinfections, meningitis, innovations
ISSN: 2072-8107
Cilt: 16
Sayı: 3
Sayfa: 5 - 9
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