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1
The Investigation of Antimicrobial Susceptibilities to the Various Antibiotics of Gram-Negative Microorganisms Isolated From Hospital Infections
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Murat DİZBAY , Dilek ARMAN
Yıl :
2005
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Antimicrobial susceptibilities to the various antibiotics of 251 gram-negative bacteria isolated from hospital infections were detected by agar dilution and E-test methods. Escherichia coli was the most common isolate among the gram-negative bacteria (31.8%). The others, isolated were respectively as Pseudomonas aeruginosa (29.5%), Acinetobacter baumannii (18.3%) ve Klebsiella spp. (13.2%). Meropenem, ciprofloxacin and cefoperazone-sulbactam were detected the most efficient three antibiotics against enteric gram-negative bacteria. In the nonfermentative group, the most efficient antibiotics were ciprofloxacin, cefoperazone-sulbactam and piperacillin-tazobactam for P. aeruginosa; and meropenem, cefoperazonesulbactam and ciprofloxacin for A. baumannii.
Anahtar Kelimeler : Hospital infection, Gram-negative bacteria, Antimicrobial drug resistance
ISSN: 1300-932X
Cilt: 10
Sayı: 1
Sayfa: 30 - 37
Sınıflandırma :
2
Çocukluk Çağı Akut Viral Hepatitlerinde Etyolojik Ajanların Dağılımı
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Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Gülnar UYSAL , Necla TÜLEK , M. Akif GÜVEN
Yıl :
1998
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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ISSN: 1300-932X
Cilt: 3
Sayı: 4
Sayfa: 274 - 275
Sınıflandırma :
3
İkibuçuk Yaşındaki Bir Çocukta Vajinal Neisseria Gonorrhoeae İnfeksiyonu
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Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Sevtap ARIKAN , Gülsevin TEKİNAY , Serpil ERCİS
Yıl :
1996
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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ISSN: 1300-932X
Cilt: 1
Sayı: 3
Sayfa: 206 - 207
Sınıflandırma :
4
Ventilatöre Bağlı Pnömoni
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Arzu TOPELİ
Yıl :
1998
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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ISSN: 1300-932X
Cilt: 3
Sayı: 4
Sayfa: 218 - 223
Sınıflandırma :
5
Semptomatik ve Asemptomatik Erkeklerdeki Klamidya İnfeksiyonlarının Klaritromisin ile Sağaltımı
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Demir SERTER , Ekin ERTEM , Deniz DERELİ , Aziz PEKER , Rüçhan SERTÖZ
Yıl :
1998
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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ISSN: 1300-932X
Cilt: 3
Sayı: 1
Sayfa: 70 - 71
Sınıflandırma :
6
Kronik Obstrüktif Akciğer Hastalığı Akut Ataklarında Antibiyotik Seçimi
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Mehmet BAKIR
Yıl :
1998
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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ISSN: 1300-932X
Cilt: 3
Sayı: 1
Sayfa: 42 - 47
Sınıflandırma :
7
Antimicrobial Resistance Patterns of Enterococcus faecalis and Enterococcus faecium Bacteria Isolated from Bloodstream Infections
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Cem ÇELİK , Elif Bilge UYSAL , Mustafa Gökhan GÖZEL , Mustafa Zahir BAKICI , Nazif ELALDI
Yıl :
2013
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Introduction: Enterococci have recently become one of the most common causes of nosocomial bloodstream infections. Today, these bacteria account for about 10% of all bacteria. This study aimed to determine the rates of resistance to antibiotics that are commonly used in the treatment of Enterococcus faecalis and Enterococcus faecium strains isolated from nosocomial bloodstream infections. Materials and Methods: The study included the E. faecalis and E. faecium strains isolated from bloodstream infections at the Practice and Research Hospital of the Faculty of Medicine, Cumhuriyet University over a total period of four and a half years between (January 2009 and June 2013). Strain typing and antimicrobial sensitivity testing were performed using an automated system (BD, Phoenix, AZ, USA) according to the guidelines of the Clinical and Laboratory Standards Institute. Nosocomial bloodstream infection diagnosis was based on the diagnostic criteria of the Centers for Diseases Control and Prevention. Results: One hundred and three enterococci strains were isolated from nosocomial bloodstream infections during the study period. 51 (49.5%) of these strains were typed as E. faecalis and 52 (50.5%) as E. faecium. While there were 44 (84.6%) ampicillin-resistant strains among E. faecium isolates, this number was 2 (3.9%) (p= 0.001) among E. faecalis strains. High-level aminoglycoside resistance rate (500 µg/mL) was higher among E. faecium isolates compared with E. faecalis isolates (63.5% vs. 33.3%; p= 0.002). While no linezoid or daptomycin resistance was noted among the strains, only 2 (1.9%) of a total of 103 enterococci strains were found to be resistant to both vancomycin and teicoplanin. Conclusion: Problems caused by the resistance of nosocomial pathogens to antimicrobials are rapidly increasing. Therefore, clinical centers should constantly update and share their available data in relation to drug resistance. We consider that the local findings of this study, conducted at a university hospital, can be used particularly in fighting against nosocomial enterococcal infections to contribute to the formation of successful empirical treatment models.
Anahtar Kelimeler : Enterococcus faecalis, Enterococcus faecium, Nosocomial bloodstream infection, Antibiotic sensitivity
ISSN: 1300-932X
Cilt: 18
Sayı: 2
Sayfa: 83 - 89
Sınıflandırma :
8
Risk of Occupational Infections Due to Occupational Exposures in Health Care Workers
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Saygın NAYMAN ALPAT , İlhan ÖZGÜNEŞ , Salih Atakan NEMLİ , Elif DOYUK KARTAL , Nurettin ERBEN , Gaye USLUER
Yıl :
2008
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Kaydet Alıntıla
Health care workers (HCWs) are exposed to the risk of occupational infections due to accidental exposures such as needlestick injuries, sharp injuries and mucosal exposure of contaminated blood or body fluids. A questionnaire was devised to determine occupational exposures (OEs) they had experienced, behaviours following OE, condition of hepatitis B virus immunization, their knowledge and compliance on universal precautions. One hundred and thirty HCWs filled out the questionnaire. One hundred and three (79.2%) of participants determined at least one or more occupational exposure during last one year. Eighteen (17.5%) of participants exposed to accidental exposure during last one year reported these exposures. One hundred and nine (83.8%) of participants had history of hepatitis B virus vaccination. Results showed that only 30 (23.1%) followed universal precautions completely.
Anahtar Kelimeler : Transmission, Healthcare worker-Patient, Wounds, Injury, Occupational diseases
ISSN: 1300-932X
Cilt: 13
Sayı: 1
Sayfa: 26 - 29
Sınıflandırma :
9
A View from Tuberculosis Laboratories of University Hospitals: The Results of A Questionnaire Study
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
J.Sedef GÖÇMEN , Altan AKSOY , Suna GEDİKOĞLU
Yıl :
2007
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Kaydet Alıntıla
A questionnaire study was performed to collect data about tuberculosis laboratories of university hospitals. Data including the physical conditions, equipment hardware, personnel knowledge, diagnostic methods applied, and the problems of the laboratories were collected by the help of a survey form in 1998, 2002 and 2006. The number of the tuberculosis laboratories which were separated and had a biosafety cabin was increased in years. Disinfection policy of the laboratories showed a great institutional variation. An increase in automated systems to detect bacilli was detected whereas conventional methods were the widespread method. At the same time, molecular tests were used increasingly and while polymerase chain reaction was the most common method. Although physical conditions and diagnostic tests of laboratories were compatible with the standards, there was no standard method for disinfection policy. It was thought that the use of moleculer methods which were prepared according to national tuberculosis controll programme was more proper.
Anahtar Kelimeler : Tuberculosis, University, Laboratory, Questionnaire
ISSN: 1300-932X
Cilt: 12
Sayı: 2
Sayfa: 86 - 91
Sınıflandırma :
10
Distribution and Evaluation of Vancomycin Resistant Enterococci Seen in Selcuk University Medical Faculty Hospital between 2012 and 2015
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Ayşe TORUN , Şua SÜMER , Onur URAL , Nazlım AKTUĞ DEMİR
Yıl :
2017
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Introduction: Prevailing at increasing rates as a cause of hospital infections in recent years, vancomycin resistant enterococcus (VRE) infections pose a serious problem in our country and across the world. This study aims at providing an overview of the VRE problem in our hospital. Materials and Methods: The data of 112 patients monitored in the clinics and intensive care units of Selcuk University Medical School Hospital between 1 January 2012 and 31 December 2015 and who had growth of VRE in their various cultures were reviewed retrospectively by going through patient files. Results: Looking at the distribution of VRE cases by years, it was seen that there were 13 cases in 2013 (11.6%), 23 cases in 2014 (20.5%) and 76 cases in 2015 (67.9%). Of these cases, 71 (63.4%) were colonized, 15 (13.4%) infected and 26 (23.2%) were both colonized and infected. The rate of infected cases was observed to be more in 2013, which was statistically significant (p< 0.001). From the 112 cases involving VRE, 36 (32.1%) were monitored in the clinics and 76 (67.9%) in the intensive care units. Thirty (83.3%) of the patients hospitalized in clinics were followed in the internal medicine clinics and 6 (16.7%) in surgical departments. The rate of colonization in patients treated in the intensive care units was higher than in those treated in clinics, which was statistically significant (p= 0.015). There was one or more underlying diseases in 109 (97.3%) of the 112 patients found to have VRE, a history of antibiotic use in 102 of them (91.1%), presence of urinary catheter in 102 (91.1%), and a history of hospitalization in 86 (76.7%). Therefore, history of hospitalization, history of underlying disease, history of antibiotic use, and presence of a urinary catheter were considered statistically significant risk factors for VRE infections (p values 0.01, 0.02, 0.01 and 0.01, respectively). E. faecium was found in 137 of the 141 isolates with VRE. Their susceptibility to antibiotics was 95.5% for linezolid and 99.2% for tigecycline. Their resistance to ampicillin and ciprofloxacin were 100%, to teicoplanin 95.7%, to trimethoprim sulfamethoxazole 89.2%, to high levels of gentamicin 87.5% and of tetracycline 80.4%. Conclusion: As a result of our study, risk factors for VRE infections were identified, which had become a growing problem in years in our hospital. It is to our belief that it would be useful, as a precaution, to take routine stool cultures from patients found to carry these risk factors.
DOI : 10.5578/flora.62932
Anahtar Kelimeler : Vancomycin resistant enterococcus, Hospital infection
ISSN: 1300-932X
Cilt: 22
Sayı: 2
Sayfa: 78 - 86
11
HBV Reactivation and Lamivudine Treatment in Patients with Lymphoma Undergoing Chemotherapy: Four Cases
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
İlhan AFŞAR , Mustafa PEHLİVAN , Aslı Gamze ŞENER , Metin TÜRKER
Yıl :
2006
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Kaydet Alıntıla
Chronic hepatitis patients undergoing immunosupressive or cytotoxic treatment may develop acute hepatitis or fulminant hepatitis due to reactivation of hepatitis B virus (HBV) and these patients may lose their lives after their treatments are discontinued. Lamivudine which was the first oral drug developed against chronic hepatitis in 1999 is a nucleoside analogue, and it shows its effect by inhibiting reverse transcriptase enzyme. Lamivudine has also been shown to be relatively safe for its side effects when compared with the interferon treatment. In this article we reported the HBV reactivation in four cases of HBV carriers with lymphoma to whom chemotherapy was applied, and the effectiveness and safety of the lamivudine treatment.
Anahtar Kelimeler : Lymphoma, Viral activation, Hepatitis B virus, Lamivudine
ISSN: 1300-932X
Cilt: 11
Sayı: 4
Sayfa: 205 - 209
Sınıflandırma :
12
Assessment of Noninvasive Methods for Prediction of Fibrosis in Patients with Chronic Hepatitis B
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Cemal BULUT , M. Arzu YETKİN , Muzaffer ÇAYDERE , F. Şebnem ERDİNÇ , Sami KINIKLI , Necla TÜLEK , Hüseyin ÜSTÜN , Ali Pekcan DEMİRÖZ
Yıl :
2007
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Kaydet Alıntıla
Noninvasive markers of liver fibrosis have been most extensively studied. The aim of this study was to evaluate and compare the diagnostic accuracies of some of these simple fibrosis tests, aspartate aminotrasferase platelet ratio (APRI), age platelet (AP) index, FIB-4 score and aspartate aminotrasferase (AST)/alanin aminotrasferase (ALT) ratio (AAR) in patients with chronic hepatitis B (CHB). Eighty male and 34 female patients were included into the study. Liver biopsy of CHB patients were evaluated histologically and significant fibrosis was defined with Scheurer fibrosis score 2 or more. All these test results were compared with liver histology. Significant fibrosis was detected in 34 patients. Older age, high serum AST and gama-glutamil transferase levels and low platelet count were found as a predictive risk factors for signficant fibrosis (p< 0.05). Only older age was found independent risk factor by multivariate analysis (p< 0.001). In patients with significant fibrosis, high levels of mean FIB-4 score, AP index and APRI were detected (p< 0.05). Area under receiver operating characteristic (ROC) curve of FIB-4 score, AP index, APRI and AAR for predicting significant fibrosis were 0.827, 0.788, 0.729 and 0.580, respectively. Existance or exclusion of significant fibrosis was reliably predicted by FIB-4 score, AP index, APRI and AAR in 75%, 77%, 33% and 67% of the patients, respectively. In conclusion, FIB-4 score and AP index were found to be the most suitable scores for predicting existance or exclusion of significant fibrosis in CHB patients. Age was found to be a significant factor indicating the presence of fibrosis, therefore it was thought that, scores using age as a component, might be more succesfull for predicting fibrosis.
Anahtar Kelimeler : Hepatitis B, Chronic, Biopsy, Fibrosis, Diagnosis
ISSN: 1300-932X
Cilt: 12
Sayı: 3
Sayfa: 128 - 134
13
Hepatitis C Virus Infection in the Patients with Type 2 Diabetes Mellitus
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Kaynak :
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Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Serpil EROL , İlyas ÇAPOĞLU , Halil YAZGI , Ömer YILMAZ , Ayten KADANALI
Yıl :
2003
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Kaydet Alıntıla
The association of hepatitis C virus (HCV) infection with diabetes mellitus (DM) is a well documented topic. However, it has been debated whether HCV infection is the additional risk factor for the development of DM or it is an associated disease. To determine the prevalence of HCV infection and associated risk factors in diabetic patients, we investigated anti-HCV antibody in the 207 patients with DM (mean age: 58.9 ± 9.3, range 38-85) and 254 control subjects (mean age: 54.0 ± 9.7, range 40-81) by ELISA method, and risk factors for HCV infection in diabetic patients. Statistical analysis was performed by chi-square test, t-test and logistic regression analysis. Anti-HCV was found positive in 16 (7.7%) of diabetic cases and 5 (2.0%) of the control subjects. According to this result, a higher seroprevalence of HCV infection was observed in patients with type 2 DM (p= 0.003). We did not detect any difference between anti-HCV positive and negative patients with respect to age, sex, duration of diabetes, hospital admission, mode of therapy and known risk factors for HCV infection (p> 0.05) whereas mean ALT levels was higher in anti-HCV positive patients (p= 0.05). The results of this study suggest that HCV infection in the diabetic patients seems a trigger factor rather than to be an associated disease.
Anahtar Kelimeler : Hepatitis C virus, Diabetes mellitus, Prevalence
ISSN: 1300-932X
Cilt: 8
Sayı: 4
Sayfa: 297 - 301
Sınıflandırma :
14
Azoles
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Kaynak :
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Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
İftihar KÖKSAL , Firdevs AKSOY
Yıl :
2008
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Azole class of antifungal agents has been used in treatment of invasive fungal infections since 1944. The azoles classified as imidazoles or triazoles according to the number of nitrogen in the azole ring. Fluconazole, itraconazole, voriconazole, posaconazole, ravuconazole, albaconazole and isavuconazole were reviewed in this manuscript.
Anahtar Kelimeler : Azole, Antifungal, Drugs
ISSN: 1300-932X
Cilt: 13
Sayı: 3
Sayfa: 111 - 121
15
Investigation of Various Methods in the Diagnosis of Systemic Aspergillosis
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Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Hafize SAV , Nedret KOÇ , Mustafa Altay ATALAY , Orhan YILDIZ , Gonca DEMİR
Yıl :
2014
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Introduction: Aspergillus infections are commonly encountered in immunocompromised patients and produce a life-threatening clinical picture. The clinical symptoms and findings may be nonspecific in these patients. The clinicians following the patients may not often find adequate time to wait for culture results or the general condition of the patient does not allow such a delay, resulting in the preference of prophylactic measures rather than specific, targeted therapies and the use of a preemptive approach based on serological and molecular documentation. The aim of the present study was to evaluate invasive aspergillosis (IA) culture, galactomannan (GM) test, 1,3 β-D glucan (BG), and real time polymerase chain reaction (rtPCR). Materials and Methods: A total of 79 patients, consisting of 42 patients with IA and 37 controls, were analyzed according to the criteria of European Organization for the Research and Treatment of Cancer and Mycoses Study Group (EORTC/MSG). Based on these criteria, three were classified as having proven IA, 10 as probable IA, and 29 as possible IA. The clinical specimens were evaluated with culture and direct microscopic examination. The fungal antigen in serum samples was studied using the GM test (Platelia Aspergillus EIA; Bio-Rad) and BG test (Fungitell, Associates of Cape Cod, USA). The rtPCR (Light Cycler-Roche, USA) test was performed to extract deoxyribonucleic acid (DNA) from serum samples. Results: Sensitivity, specifity, positive predictive value (PPV) and negative predictive value (NPV) were respectively calculated as 78%, 78%, 80% and 76% for IA diagnosis for BG test (cut-off 80 pg/mL). BG value was detected as 80 pg/mL and over in at least one of the samples of 8 patients without IA. GM test was studied from the same samples and sensitivity, specifity, PPV and NPV were (cut-off 0.5 ng/mL) 47%, 89%, 83% and 60%, respectively. Positivity was detected in the samples of five control patients with GM test. A molecular method, rtPCR, was studied from these samples as well as serological methods and sensitivity, specifity, PPV and NPV of the test were 30%, 86%, 72% and 52%, respectively. Positivity was detected in serum samples of five control patients with rtPCR. Conclusion: As a result, sensitivity of BG and specifity of GM were detected as the highest ones of all BG, GM, rtPCR tests in this study. For IA diagnosis, it is emphasized that these tests should be evaluated with clinical and radiological findings to increase the significance of the non-cultural methods.
Anahtar Kelimeler : Galactomannan, Real-time polymerase chain reaction, Aspergillosis
ISSN: 1300-932X
Cilt: 19
Sayı: 2
Sayfa: 66 - 73
Sınıflandırma :
16
Investigation of Susceptibility of Mycobacterium tuberculosis Complex Strains Isolated from Clinical Samples Against the First and Second-Line Anti-tuberculosis Drugs by the Sensititre MycoTB Plate Method
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Figen KAYSERİLİ ORHAN , Ayşe Esin AKTAŞ , Nimet YİĞİT
Yıl :
2018
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Introduction: Phenotypic methods for drug susceptibility testing of Mycobacterium tuberculosis complex (MTC) to second-line drugs are not yet standardized. The Sensititre MycoTB Plate is a microtiter plate containing lyophilized antibiotics and configured for determination of MIC to first and second-line anti-tuberculosis drugs. The purpose of this study is to detect the susceptibility rates of MTC strains isolated from patients’ specimens for first and second-line anti-tuberculosis drugs. Materials and Methods: This study included 50 MTC strains isolated from various clinical specimens. Out of the 50 strains, 38 were isolated from sputum, three from cerebrospinal fluid, three from bronchoalveolar lavage, and six from other samples in this study. The susceptibility of strains to anti-tuberculosis drugs were determined by the Sensititre MycoTB Plate Method. Thawed isolates were subcultured, and dilutions were inoculated into MycoTB wells. The results were read at days 7, 14 and 21. Results: At the end of study, out of 50 MTC isolates, 7 (14%) showed resistance to Isoniazid (INH), 5 (10%) to streptomycin (SM), 4 (8%) to ethambutol (EMB), 4 (8%) to ethionamide (ETH), 3 (6%) to rifampicin (RIF), 3 (6%) to rifabutin (RFB), 2 (4%) to kanamycin (KAN), 2 (4%) to ofloxacin (OFL), 2 (4%) to P-aminosalicyclic acid (PAS), 1 (2%) to moxiflocacin (MOX), and 1 (2%) to cycloserine (CYC). All strains were found sensitive to amikacin while 2 strains (4%) were identified as multidrug-resistant tuberculosis (MDR-TB). Thirty-five strains (70%) were sensitive to all drugs. Extensively drug resistant tuberculosis (XDR-TB) was not determined in this study. Conclusion: This is the first study that tests second line anti-tuberculosis drugs in our location and provides us valuable data regarding MDR-TB and XDR-TB rates. The Sensititre MycoTB Plate Method is a fast, reliable and practical method and can be used to determine the susceptibility of first and second-line anti-tuberculosis drugs.
DOI : 10.5578/flora.66414
Anahtar Kelimeler : MDR-TB, XDR-TB, Mycobacterium tuberculosis complex, Sensititre MycoTB Plate
ISSN: 1300-932X
Cilt: 23
Sayı: 1
Sayfa: 31 - 38
Sınıflandırma :
17
Determination of the Knowledge, Attitudes and Behaviors of Adults At and Over the Age of 18 On Vaccines and Vaccination
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Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Mehmet UYAR , Elif Nur YILDIRIM , Tahir Kemal ŞAHİN
Yıl :
2019
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Introduction: The aim of this study was to determine the knowledge, attitudes and behaviors of adults aged 18 years and older about vaccines and vaccination and to establish vaccine hesitancy and vaccine rejection rates in the population. Materials and Methods: This cross-sectional study was conducted in five primary care clinics in Meram, Konya. The sample size of the study was 130. Between 10 and 31 October 2018, 134 subjects aged 18 and over who applied to the primary care clinics for any reason were included into the study. For the research, a data collection form consisting of 23 questions was developed by the researchers. The data collection form was applied to the participants by face-to-face interview method. Data entry, statistical analysis and report writing were done with computer. In summarizing numerical data, arithmetic mean, standard deviation, minimum and maximum values were used, and in summarizing categorical data, frequencies and percentages were used. Results: 52.2% of the participants were females, 59% were married and 35.1% were high school graduates. 79.9% of the volunteers knew at least one vaccine-protected disease, 44.8% of them knew at least one vaccine in the vaccination chart and 16.4% of them knew at least one vaccine not included in the vaccination chart. 93.9% of the participants thought that vaccination is necessary. 65.3% of the participants learned about vaccines from health care workers. There was no one who refused all vaccinations among the people involved in the research. We found that 9% of the study group had vaccine hesitancy. 84% of the respondents stated that they would like to vaccinate themselves and their children if the vaccine was produced in our country. Conclusion: As a result of the study, it was found that the participants had a positive attitude about vaccines and vaccination. No vaccine rejection was observed in our study group, but it was found that there was a 9% vaccine hesitation. There was a high-level support in the participants for the production and use of native Turkish vaccines.
DOI : 10.5578/flora.68195
Anahtar Kelimeler : vaccine hesitancy, vaccine rejection, vacination, public health
ISSN: 1300-932X
Cilt: 24
Sayı: 4
Sayfa: 288 - 294
Sınıflandırma :
18
The Role of Antibiotic Treatment Alone for the Management of Brucella Endocarditis: A Case Report and Literature Review
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Ali MERT , Funda KOÇAK , Reşat ÖZARAS , Fehmi TABAK , Muammer BİLİR , Recep ÖZTÜRK , Yıldırım AKTUĞLU
Yıl :
2002
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
Endocarditis is a rare complication of brucellosis but it is the main cause of mortality in this disease. The accepted treatment for Brucella endocarditis is a combination of valve replacement and antibiotics. Conservative antibiotic treatment alone is not recommended by most of the authors as it is considered ineffective and to be increasing the risk of fatality. In our literature review, we have found 14 patients with brucellosis endocarditis treated with antibiotics alone with a favorable outcome. In this report, we described a patient treated with antibiotics alone and reviewed the literature. Depending on the data from the current literature and our patient we suggest that in selected patients with Brucella endocarditis who do not have congestive heart failure, valve destruction, abscess formation, or a prosthetic valve, conservative antibiotic treatment may be a valid alternative to surgery.
Anahtar Kelimeler : Brucellosis, Endocarditis
ISSN: 1300-932X
Cilt: 7
Sayı: 1
Sayfa: 63 - 67
Sınıflandırma :
19
The Comparison of the BBL-Mycobacteria Growth Indicator Tube (MGIT) with Löwenstein-Jensen Culture Media and Evaluation of the Resistance of the Isolated Strains Against Four Major Drugs
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Bekir KOCAZEYBEK
Yıl :
2002
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
In our study, it is aimed to compare the Mycobacteria Growth Indicator Tube (MGIT) which detects the presence of Mycobacteria rapidly with the reference method Löwenstein-Jensen (LJ) in clinical samples having suspect of pulmonary and extrapulmonary tuberculosis and to determine the resistance of the isolated strains against four major antimicrobial drugs and to evaluate the primary and secondary resistances of the cases. Six-hundred and forty-eight clinical samples from different clinics suspected of pulmonary tuberculosis (PT) or extrapulmonary tuberculosis (EPT) according to the clinical, radiological, histopathological and immunological findings were investigated. The samples were first stained with Ziehl-Neelsen (ZN) method, then, cultured in LJ according to the standard bacteriological rules and in MGIT tubes as recommended by the manufacturer. Conventional biochemical tests and NAP (p-nitro-alpha-acethylamino-beta-hydroxypropiophene) of BACTEC System were used to identify isolated mycobacterial strains. The BBL-MGIT antimicrobial susceptibility test (AST) was performed to detect susceptibility to streptomycine (S), isoniazid (H), rifampicin (R), ethambutole (E) (SIRE) and the strains which were found resistant to any of the drugs were confirmed by performing agar proportion method. Mycobacterium spp. were isolated in 61 (9.4%) out of 648 samples. After species identification, 58 out of 61 strains were found as M. tuberculosis and other three as M. tuberculosis complex (MTC). Thirty-two samples which were isolated in the culture were ZN positive and the growth time was 12.2 days in MGIT, 24.1 days in LJ (p< 0.001). Twenty-nine were ZN negative and their growth time was 23 days in MGIT, 37 days in LJ (p< 0.001). In 61 cases consisting of 39 newly and 22 pleviously diagnosed patients, drug resistance were seen in 23 (37.7) which were 8 (20.51%) as primary and 15 (68.18%) secondary resistance. In one drug resistance, both primary and secondary resistance were detected whereas in 2 drug resistance, secondary resistance was seen in only H + R pattern (4 cases). The highest cumulative drug resistance was found against H as both primary and secondary resistance. Our study emphasizes that MGIT has high sensitivity and specificity, performs antimicrobial susceptibility test, is easy to perform and is a more rapid method than LJ, so it is evaluated as an advantage in rapid bacterial identification of tuberculosis and in establishing antimicrobial resistance the importance of its application in routine laboratory work is underlined. In addition to these, our study makes us think that the high ratio of secondary resistance in public may be related to in compliance of patients or insufficiency of therapy and this may cause a serious raise of primary tuberculosis with new contaminations.
Anahtar Kelimeler : Mycobacterium tuberculosis, Drug resistance
ISSN: 1300-932X
Cilt: 7
Sayı: 2
Sayfa: 112 - 119
Sınıflandırma :
20
ERCP Related Sepsis
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
İffet PALABIYIKOĞLU , Emin TEKELİ , Derya AYSEV , Mustafa ŞIRLAK , Sibel KAYMAKÇI , Sultan DOĞANAY
Yıl :
2005
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
Endoscopic procedures performed worlwide have increased considerably in recent years. In addition to diagnosis, many cases previously necessitating surgery now often can be carried out by endoscopic techniques. However, endoscopy has introduced its own infection risks. Most reports of gastrointestinal endoscopy-associated infection describe sepsis after endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary tract obstruction. During this study which was conducted by Infection Control Committee of Ankara University Hospital, 13 out of 1147 (1.1%) and 17 out of 922 patients (1.8%) had ERCP related sepsis in 2002 and 2003 respectively, at the ERCP Unit of Gastroenterology Department. Sepsis caused mortality was 23.1% and 29.4% in 2002 and 2003 respectively. The first three causative agents were Escherichia coli, Pseudomonas spp. and, Klebsiella + Enterobacter spp. Type and frequency of the causative agents remind that both endogenous and exogenous mechanisms are together responsible for the infections emerging from ERCP unit. Besides, increasing isolation of Pseudomonas spp. brings out the strong need for reevaluation of infection control measures, mainly effective cleansing and disinfection of endoscopes.
Anahtar Kelimeler : Endoscopy, Disinfection, Infection, Complication
ISSN: 1300-932X
Cilt: 10
Sayı: 2
Sayfa: 88 - 91
21
The Role of Procalcitonin in Diagnosis of Different Bacterial Infections
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Semra TUNÇBİLEK , Nurcan BAYKAM , Kenan HIZEL , Başak DOKUZOĞUZ
Yıl :
2000
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
It is reported that procalcitonin (PCT), the precursor of calcitonin is elevated in patients with severe bacterial infections. In this study our aim is to determine the value of PCT in different bacterial infections and sepsis as a marker of infection. Six brusellosis, 8 systemic salmonellosis, 9 bacterial meningitis, 11 sepsis, total 33 patients and 20 healthy adults as control group were included in the study. PCT value was measured and compared by diagnostic value of C-reactive protein (CRP). PCT determination was performed by immunoluminometric assay (Brahms Diagnostica Lumitest, PCT, Berlin). A significant difference was found between all patients and control group for both tests. There were significant differences between PCT concentrations in sepsis and other bacterial infections but no difference was found for CRP. PCT levels increased in patients with bacterial infections like CRP but PCT was a more valuable marker than CRP for indicating the severity of infection.
Anahtar Kelimeler : Procalcitonin, Sepsis, Brucellosis, Salmonellosis, Meningitis
ISSN: 1300-932X
Cilt: 5
Sayı: 2
Sayfa: 99 - 103
Sınıflandırma :
22
Are Lower Extremity Re-amputations in Diabetic Foot Inevitable?
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Ilgın Yıldırım Şimşir , Anıl Murat Öztürk , Yakut Shamistanli , Meltem Taşbakan , Şevki Çetinkalp
Yıl :
2018
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yayıncı Web Sitesi
Tam Metin
Kaydet Alıntıla
Introduction: A major complication of diabetes, which is increasing in the World, is the development of diabetic foot wound. Diabetic foot wounds can cause serious morbidity and even mortality in patients. In the treatment of diabetic foot wounds, surgical treatment is usually necessary besides medical treatment. Lower limb amputation rates in diabetic patients are much higher than non-diabetic patients. Re-amputations may be unavoidable due to underlying risk factors. In this study, it was aimed to determine the re-amputation rates in diabetic foot wound cases. Materials and Methods: We reviewed retrospectively the medical records of diabetic patients admitted to the Diabetic Foot Care Center of Ege University Medical Faculty between 2015-2018. Results: In this period, re-amputation was performed on 50 patients (17.9%) from a total of 280 patients who were followed up at the center. Mean re-amputation time was calculated ± SD 1.7 ± 2.1 years, median (min-max) 1 (0.08-10.0) year. During admission, re-amputation odds ratio was found to be increased by 1.9 and 2.3 times in cases with Wagner 4 and 5, respectively. Conclusion: Diabetic foot infections and limb amputations as a result seriously reduce the quality of life of the patients. The risk of re-amputation increases when the ulcer Wagner’s grade is raised. In order to decrease the rate of amputations, it is necessary to provide foot care training to every patient diagnosed with diabetes, and if amputation is inevitable, it is also necessary to identify risk factors and take essential precautions after the operation.
DOI : 10.5578/flora.67491
Anahtar Kelimeler : Diabetic foot, Amputation, Re-amputation
ISSN: 1300-932X
Cilt: 23
Sayı: 4
Sayfa: 202 - 207
Sınıflandırma :
23
Evaluation of 17 Cases of Adult Tuberculous Meningitis
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Yeşim TAŞOVA , Neşe SALTOĞLU , Akgün YAMAN , Arzu ASLAN , İsmail H. DÜNDAR
Yıl :
1997
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
Adult tuberculous meningitis is an extra-pulmonary form of tuberculosis which, because of a rapid course and neurological sequela, leads to high morbidity and mortality. For this reason, an early diagnosis is important but is not always possible. The aim of this study, which was carried out between 1991-1995, was to evaluate the factors affecting the prognosis of diseases in patients which had been diagnosied as tuberculous meningitis using the patients history, clinical picture, and laboratory and radiological findings. Fifty nine percent of the patients were between 25-45 years of age. The rate of mortality in these patients 47% and when they were admitted to the hospital, 62.5% were in the second stage of the disease. In 15 (88.2%) of all patients, the symptoms had occurred 2 weeks or more before hospitalization. In the microscobic examination of CSF of 5 (29.4%) of the patients, acid fast bacilli were seen. However, M. tuberculosis grew in the cultures of CSF of only 2 of these. Evidence of active or previous pulmonary tuberculosis was found in 4 (23.5%) of our patients. Ventriculoperitoneal shuts were placed in 3 out of 8 patients who developed hydrocephalus. Multipl tüberculomas which decreased with antituberculous treatment were detected in 2 patients during treatment. In conclusion, in patients with tuberculous meningitis, the most important factors affecting the prognosis is the time between the development of symptoms and treatment as well as the neurologic phase.
Anahtar Kelimeler : Tuberculous Meningitis, Adult, Prognostic Factors
ISSN: 1300-932X
Cilt: 2
Sayı: 1
Sayfa: 55 - 60
Sınıflandırma :
24
Investigation of JC Virus Positivity By Real-time Polymerase Chain Reaction in Patients with Hematopoietic Stem Cell Transplant
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Meryem ÇOLAK , Aylin ALTAY KOÇAK , Lale AYDIN KAYNAR , Zübeyde Nur ÖZKURT , Zeynep Arzu YEĞİN , Gülendam BOZDAYI
Yıl :
2020
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yayıncı Web Sitesi
Tam Metin
Kaydet Alıntıla
Introduction: In immunocompromised hosts, JC virus (JCV) can reactivate and cause a lytic infection of oligodendrocytes, resulting in progressive multifocal leukoencephalopathy (PML). Bone marrow is an important reservoir and possible site of neurotropic transformation for JCV. The aim of this retrospective study was to investigate the prevalance of JCV infection by real-time polymerase chain reaction (PCR) in patients sent from bone marrow transplant service to the laboratory in our hospital. Materials and Methods: A total of 153 clinical samples obtained from 62 patients with hematopoietic stem cell transplant between December 2013 and April 2018 were included into the study. Viral nucleic acids were extracted from the samples with QIAamp DSP Virus Kit in EZ1 Advanced (Qiagen, Germany) device. Isolated viral DNA was amplified with Real Star® JCV PCR Kit in Rotor-GeneQ (Altona, Germany) and JCV DNA was detected with qualitative method. Results: Sixty-two patients, 35 (56.5%) males and 27 (43.5%) females, between 18 years and 71 years of age were included into the study. Total JCV DNA positivity rate was found as 11.1% (17/153). Patients’ diagnosis was respectively as follows: 45.2% acute myeloid leukemia, 19.4% acute lymphoblastic leukemia, 9.7% multiple myeloma. 6.4% myeloblastic sendrome, 6.4% non-Hodgkin lymphoma, 6.4% Hodgkin lymphoma, and 6.4% anemia. The distribution of JCV DNA positivity rates was found respectively as 40% acute myeloid leukemia, 30% multiple myeloma, 10% Hodgkin lymphoma, 10% acute lymphoblastic leukemia and 10% Non-hodgkin lymphoma. It was observed that 50% of JCV DNA positive patients died in the follow-up period after hematopoietic stem cell transplantation. Conclusion: It is not possible to diagnose JCV infections clinically because they are usually asymptomatic. However, up to 90% of those diagnosed with PML die within the first six months receiving a diagnosis. Detection and clinical surveillance JCV DNA by real-time PCR for hematopoietic stem cell transplantation patients is important for early diagnosis and treatment.
DOI : 10.5578/flora.68466
Anahtar Kelimeler : jc virus, immunosuppressive patient, hematopoietic stem cell transplant, real-time polimerase chain reaction
ISSN: 1300-932X
Cilt: 25
Sayı: 1
Sayfa: 40 - 46
Sınıflandırma :
Biyotıp %100
Hematoloji %100
25
Seroprevalence of Hepatitis Delta Infection: Retrospective-Based Seroepidemiologic Assessment
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Sena İZMİRLİ , Deniz Gözde ÇELİK , Zeynep GÜNGÖRDÜ , Tevhide ZİVER , Mustafa ASLAN , Suat SARIBAŞ , Reyhan ÇALIŞKAN , Pelin YÜKSEL , Bekir KOCAZEYBEK
Yıl :
2011
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
Introduction: Hepatitis delta virus (HDV) is an important viral agent that causes co-infection or superinfection with hepatitis B virus (HBV). In this study we evaluated anti-HDV positivity in 6707 acute, chronic and asymptomatic cases between January 2005 and July 2010. Materials and Methods: HBV and HDV tests were performed with different commercial enzyme-linked immunosorbent assay (ELISA) kits. Results: We determined anti-HDV positivity in 308 (4.5%) of 6707 HBsAg positive, 3.2% of 28 acute HBV, 4.4% of 4320 chronic HBV, and 5.1% of 2359 asymptomatic patients. Anti-HDV rates showed no distinctive percentage distribution among gender and age groups. Conclusion: Anti-HDV rates in HBsAg-positive patients in Istanbul were determined to be lower than the moderate endemicity areas rates predicted for Turkey.
Anahtar Kelimeler : Hepatitis delta virus, Co-infection, Superinfection, Seroprevalence
ISSN: 1300-932X
Cilt: 16
Sayı: 3
Sayfa: 120 - 126
Sınıflandırma :
26
The Prevalence of Leptospirosis in Human Beings and Rats in Samsun
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
İrfan ŞENCAN , Hakan LEBLEBİCİOĞLU , Mustafa SÜNBÜL , Şaban ESEN , Cafer EROĞLU , Murat GÜNAYDIN
Yıl :
1999
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
Leptospirosis is a worldwide zooanthroponosis and also it is an important public health problem in Samsun Turkey. The purpose of this study is to know the prevalence of leptospirosis in humans and rats. Serum samples for serology were obtained from 279 people with the risk of leptospirosis (e,g. farmers, veterians, rice-field workers) and 200 people with no risk. Sera of all the human and 10 rats were tested for the presence of leptospiral agglutinins by microscopic agglutination test (MAT) using the following four leptospiral antigens; L. interrogans icterohaemorrhagiae, L. interrogans grippotyphosa, L. interrogans sejroe hardjo and L. biflexa semaranga patoc I. A titer of 1/100 and above for rats and 1/20 and above for epidemiological survey was considered as positive. A total of 4.3% of the risky group and 0.05% of controls were seropositive with using MAT. The difference being significant in risky group (p < 0.05). The serovars detected were 7 (58.3%) L. grippotyphosa, 5 (41.7%) L. icterohaemorrhagiae. Among 28 rats examined for evidence of leptospiral infection by dark field microscopy, silver staining, MAT and culture, the evidence of Leptospira infection was demonstrated in 53.6% of them by at least one method. Three rats were identified as serovar L. icterohaemorrhagiae (2 MAT, 1 culture). Leptospirosis is a frequent zoonosis in this area and leptospirosis should be considered as a possible diagnosis in febrile diseases in occupational groups such as farmers, veterians and rice-field workers.
Anahtar Kelimeler : Leptospira, Leptospirosis, Weil disease
ISSN: 1300-932X
Cilt: 4
Sayı: 1
Sayfa: 58 - 63
27
Risk Factors for Mortality in Patients with Candidemia: A Prospective Case-Control Study
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Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Evrim GÜLDEREN , Esragül AKINCI , Pınar ÖNGÜRÜ , Hürrem BODUR
Yıl :
2010
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
Introduction: Candidemia is a serious infection with a high mortality rate. Patients and Methods: This prospective case-control study was conducted between January 2004 and December 2007. Hospitalized patients who had Candida spp. in their blood cultures were followed until death or discharge. Mortality was considered to be related to candidemia if the patient was receiving antifungal treatment for candidemia when death occurred or if they died before initiation of antifungal agent, if no other cause of death was detected. Variables of the patients with candidemia-related death and the patients who survived after a candidemia episode were compared statistically for the detection of candidemia-related mortality risk factors. Results: A total of 124 patients were included in the study. The overall candidemia-related mortality was 66.1%. Univariate predictors associated with mortality were age ≥ 65 years, hospitalization in the intensive care unit (ICU), sepsis syndrome during the candidemia episode, Acute Physiologic Assessment and Chronic Health Evaluation (APACHE) II score ≥ 10, presence of central venous catheter during candidemia, central venous catheter not removed after development of candidemia, total parenteral nutrition, Candida albicans etiology, and lack of antifungal therapy. In the multivariate analysis, age ≥ 65 years, hospitalization in ICU, sepsis syndrome during the candidemia episode, C. albicans etiology, and lack of antifungal therapy were independent factors adversely influencing outcome. Conclusion: This study suggested that candidemia-related mortality can be reduced by starting empirical antifungal treatment in the high-risk ICU patients with refractory fever, especially for those under broad-spectrum antibiotics, and by removing the central venous catheter as a part of the treatment.
Anahtar Kelimeler : Candida, Mortality, Risk factors
ISSN: 1300-932X
Cilt: 15
Sayı: 2
Sayfa: 59 - 67
Sınıflandırma :
28
Diarrhea with Blastocystis hominis in a Leukemic Patient
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Gökhan AYGÜN , Şeniz ÖNGÖREN , Recep ÖZTÜRK , Burhan FERHANOĞLU
Yıl :
2001
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
An acute diarrhea caused by Blastocystis hominis was determined in a leukemic patient and cured with metronidazole therapy. Clinical significance of B. hominis was investigated.
Anahtar Kelimeler : Blastocystis hominis, Diarrhea, Leukemia
ISSN: 1300-932X
Cilt: 6
Sayı: 1
Sayfa: 62 - 64
Sınıflandırma :
29
Aspergilloma Occurred in Preexisting Tuberculous Cavity in a Patient with Acquired Immune Deficiency Syndrome
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Evrim GÜLDEREN , Gökhan GÖZEL , Ayşe ERBAY , Pınar ÖNGÜRÜ , Meltem HÜNER , Mustafa Aydın ÇEVİK , Hürrem BODUR
Yıl :
2008
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
Aspergillus fungus balls develop preexisting cavities in the pulmonary apex of patients with chronic lung disease such as tuberculosis. Acquired Immune Deficiency Syndrome (AIDS) predisposes to reactivation of tuberculosis. Efficacy of antifungal therapy in invasive aspergillosis has been extremely poor in immunsupressed patients such as AIDS. An aspergilloma case developing on the preexisting tuberculosis cavity in the 36 years old patient who was followed up as AIDS is evaluated in this case report.
Anahtar Kelimeler : Aspergilloma, Tuberculosis, Fungus
ISSN: 1300-932X
Cilt: 13
Sayı: 4
Sayfa: 209 - 213
Sınıflandırma :
30
Lung Abscess in Crimean-Congo Hemorrhagic Fever: A Case Report
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
Directory of Open Access Journals (DOAJ)
Dergi:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Yazar(lar) :
Şule ÇINAR , Gülden BİLGİN , Necla TÜLEK , Metin ÖZSOY , Çiğdem MOROĞLU , F. Şebnem ERDİNÇ , Günay TUNCER ERTEM
Yıl :
2016
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Tam Metin
Kaydet Alıntıla
Crimean-Congo hemorrhagic fever is a viral zoonotic infection that affects multiple organs and systems, and causes various complications and death. Here, we present a case of a Crimean-Congo hemmorrhagic fever with pulmonary abscess complication, which has not been previously reported.
Anahtar Kelimeler : Crimean-Congo hemorrhagic fever, Complications, Abscess
ISSN: 1300-932X
Cilt: 21
Sayı: 1
Sayfa: 38 - 41
Sınıflandırma :

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