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An association study of functional polymorphic genes IRF-1, IFNGR-1, and IFN-? with disease progression, aspartate aminotransferase, alanine aminotransferase, and viral load in chronic hepatitis B and C
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
International Journal of Infectious Diseases
Yazar(lar) :
M. Korachi , N. Ceran , R. Adaleti , A. Nigdelioglu , M. Sökmen
Konu :
Genetic polymorphisms, Hepatitis, IFN-?, IFNGR-1, IRF-1, Viral load
Yıl :
2013
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Background: Investigational approaches based on genome-wide association studies have proven useful in identifying genetic predictors for many diseases, including susceptibility to chronic hepatitis B and C. In these studies, the majority of genetic variants that have shown a positive association have been identified in genes involved in the immune response. In this study IFN-?, IFNGR-1, and IRF-1 genes were analyzed for their role in susceptibility to the development of chronic hepatitis B and chronic hepatitis C in a Turkish population. Methods: Polymorphic genes IRF-1 (-410, -388), IFNGR-1 (-56, -611), and IFN-? (+874) were analyzed in a total of 400 individuals: 100 chronic hepatitis B patients, 100 hepatitis B carriers, 100 chronic hepatitis C patients, and 100 healthy controls. A single base primer extension assay was used. Correlations between genes and gender, viral load, and aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were also investigated. Results: The IRF-1 gene at positions -388 and -410 were observed to be candidate gene markers for susceptibility to the development of chronic hepatitis B and C (p< 0.05). IFN-? +874 and IFNGR-1 (-56 and -611) correlated with chronic hepatitis B but not chronic hepatitis C. Correlation of functional genotype with viral load and AST and ALT levels revealed an association of IFN-? +874 and IFNGR-1 -611 with chronic hepatitis C and IFN-? +874 with viral load and chronic hepatitis B (p< 0.05). Conclusions: Findings suggest that IFN-? (+874), IRF-1 (-410, -388), and IFNGR-1 (-56, -611) are candidate gene markers for determining patient susceptibility to the development of chronic hepatitis B and C. © 2012 International Society for Infectious Diseases.
Anahtar Kelimeler : Genetic polymorphisms, Hepatitis, IFN-?, IFNGR-1, IRF-1, Viral load, article

ISSN: 12019712
2
Anti-Saccharomyces cerevisiae (ASCA) antibody levels in a subgroup of patients with ulcerative colitis, Crohn's disease, GI Behcet, and GI tuberculosis: Correlations with disease duration, activity, and extension
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yazar(lar) :
G. Hatemi , Y. Erzin , H. Yazici , M. Aslan , I. Hatemi , A. Celik , B. Kocazeybek
Konu :
Yaşam Bilimleri, Temel Bilimler, Yaşam Bilimleri (LIFE), İmmünoloji, BULAŞICI HASTALIKLAR
Yıl :
2021
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : Yaşam Bilimleri, Temel Bilimler, Yaşam Bilimleri (LIFE), İmmünoloji, BULAŞICI HASTALIKLAR, Makale

ISSN: 1201-9712
Sınıflandırma :
3
Comparison of the incidence of dientamoeba fragilis in a cohort of paediatric children with allergic asthma and aontrols: Is it a pathogen or protector?
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yazar(lar) :
S. Nepesov , E. Bonabi , M. Demirci , S. O. Okullu , O. Kurt , G. Ayaz , H. Kirkoyun Uysal , Y. A. Oner , A. Karakullukcu , H. Bahar Tokman , B. Kocazeybek , S. Saribas , H. Cokugras
Konu :
İmmünoloji, Yaşam Bilimleri (LIFE), Yaşam Bilimleri, Temel Bilimler, BULAŞICI HASTALIKLAR
Yıl :
2021
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : İmmünoloji, Yaşam Bilimleri (LIFE), Yaşam Bilimleri, Temel Bilimler, BULAŞICI HASTALIKLAR, Makale

ISSN: 1201-9712
Sınıflandırma :
Çevre %54
Fizik %27
4
Pamuklu Tekstil Atıksuyunun Pilot Ölçekli Membran İle Arıtımı ve Geri Kullanımı: Tekstil Kalitesine Etkileri
Bildiri Serisi

Bildiri Serisi
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yazar(lar) :
GÜLER TÜRKOĞLU DEMİRKOL , Sema Palamutçu , HÜSEYİN SELÇUK , BURAK YÜZER , MUHAMMED İBERİA AYDIN , Fatma Burçak Bulut , Türkan Ormancı , S Pak
Konu :
Tarım ve Çevre Bilimleri (AGE), Çevre / Ekoloji, Tarımsal Bilimler, Ziraat
Yıl :
2021
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : Tarım ve Çevre Bilimleri (AGE), Çevre / Ekoloji, Tarımsal Bilimler, Ziraat, Bildiri
Sınıflandırma :
Kimya %89
5
Treatment of mucormycosis with liposomal Amphotericin B, posaconazole and deferasirox: A case report
Konferans Makalesi

Konferans Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Sipahi O. R. , Onal U. , Tasbakan M. , Yamazhan T. , Arda B. , Pullukcu H. , Ulusoy S.
Yıl :
2014
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : conferenceObject
Cilt: 21
ISSN: 1201-9712
Sınıflandırma :
6
Design and Development of a Novel Electrochemical DNA Biosensor for Rapid Molecular Identification of Enterococcus faecium
Konferans Makalesi

Konferans Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Chan Y. Y. , Balqis K. , Dilsat A. O. , Lee S. Y. , Lalitha P. , Ozsoz M. , Ravichandran M.
Yıl :
2008
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : conferenceObject
Cilt: 12
ISSN: 1201-9712
Sınıflandırma :
Kimya %100
Enzimoloji %72
7
Varicella rates among unvaccinated and one-dose vaccinated healthy children in Izmir, Turkey
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Kurugol Zafer , Halicioglu Oya , Koc Feyza , Koturoglu Guldane , Aksit Sadik
Konu :
Varicella, Varicella vaccine, Breakthrough varicella, Risk factors
Yıl :
2011
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Objectives: We aimed to determine the rate of breakthrough varicella in Turkey, a country with low varicella vaccination coverage. Methods: This study was conducted between April 2008 and March 2009 at the Well-Child Clinic at Ege University and pediatricians' offices. We collected information on vaccination status and varicella infection using a questionnaire. In order to elicit more details about the severity of illness, we interviewed all parents and reviewed the clinician records. Vaccination status was verified from the medical records or vaccination cards with dates. Results: A total of 2802 children were evaluated. Of these, 1683 had been vaccinated with a single dose of varicella vaccine and 1119 were unvaccinated. Among vaccinated children, 466 (27.7%) had breakthrough varicella. Vaccinated children tended to have mild varicella. However, about 25% of breakthrough cases had moderate or severe disease. Children who were vaccinated >= 5 years previously had a 3.7-fold higher risk of breakthrough disease than those who were vaccinated <5 years before. Vaccination at younger than 15 months of age was not significantly associated with an increased risk of breakthrough infection. Conclusions: Breakthrough varicella is not rare in Turkey where varicella infections are common. A longer interval since vaccination may be a risk factor for developing breakthrough varicella. Children who had been vaccinated >5 years previously were at risk for breakthrough disease. A two-dose varicella vaccine policy may be needed to provide improved protection. (C) 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Anahtar Kelimeler : Varicella, Varicella vaccine, Breakthrough varicella, Risk factors, article
Cilt: 15
Sayı: 7
ISSN: 1201-9712
8
Screening for human immunodeficiency virus type 1 and 2 in a Turkish blood donor population
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
BC Decker Inc.
Yazar(lar) :
Altuglu I. , Sayiner A.A. , Erensoy S. , Zeytinoglu A. , Bilgiç A.
Konu :
Blood donors, HIV, Turkey
Yıl :
1998
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Objectives: To determine the prevalence of human immunodeficiency virus- 1 and -2 infection in voluntary blood donors at a university hospital in the third largest city of Turkey and to evaluate the HIV testing strategy for notifying blood donors. Methods: Between July 1995 and August 1997, 36,373 voluntary blood donors who met the criteria for donating blood were tested for the presence of HIV-1 and -2 antibodies by using an automated enzyme- linked fluorescent immunoassay. Repeatedly reactive samples were subjected to a different enzyme-linked immunosorbent assay (ELISA) and a line immunoassay (LIA) for the detection of antibodies. Results: Of the 36,373 samples tested 72 were found to be repeatedly reactive or borderline by the first screening enzyme immunoassay (EIA). None of the 72 samples was reactive by the second EIA. These samples were further tested by LIA: 64 were negative on the line immunoassay and 8 were indeterminate. Three of eight donors who had indeterminate results by LIA were tested for HIV-1 DNA by polymerase chain reaction (PCR) and were found to be negative. One additional donor with an indeterminate LIA was found to be negative by EIA and LIA during the 6-month follow-up period. Conclusion: Donor questioning, repeat EIA testing, LIA testing, and HIV-1 DNA analysis did not confirm evidence for HIV infection among this blood donor population. Blood donor notification of test results according to the World Health Organization (WHO) strategy III was found to be an appropriate approach.
Anahtar Kelimeler : Blood donors, HIV, Turkey, article
Cilt: 2
Sayı: 4
ISSN: 1201-9712
Sınıflandırma :
Viroloji %99
9
Utility of the serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Avcu Gulhadiye , Karapinar Deniz Yilmaz , Akinci Ayse Burcu , Sivis Zuhal Onder , Sahin Akkiz , Bal Zumrut Sahbudak , Polat Suleyha Hilmioglu , Metin Dilek Yesim , Vardar Fadil , Aydinok Yesim
Konu :
Galactomannan, Aspergillosis, True-positive, False-positive, Children, Acute lymphoblastic leukemia
Yıl :
2017
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Objectives: Invasive aspergillosis (IA) is an important cause of mortality and morbidity in children with hematological malignancies. The monitoring of serum galactomannan (GM) antigen is considered useful in the diagnosis of IA. The aim of this study was to determine the utility of serum GM monitoring in the early diagnosis of IA and the role of positive antigenemia in the management of children with acute lymphoblastic leukemia (ALL). Methods: The cases of 141 children who were being treated for ALL in the Division of Pediatric Hematology of the Medical School of Ege University between January 2006 and February 2015 were reviewed retrospectively. Cases of proven and probable IA were defined according to the European Organization for the Research and Treatment of Cancer/Mycoses Study Group (EORTC/MSG) criteria. Results: The incidence of proven and probable IA was 3.5% (5/141). The incidence of positive GM antigenemia among 3264 serum samples was 5.5% (n = 179). Of the cases detected, 21.7% were truepositive, 52.1% were false-positive, and the remaining 26.1% were classified as 'undetermined.' An increase in the incidence of true-positive tests and induction of antifungal therapy was determined through multiple consecutive positive tests. Conclusions: GM may be detected in the serum before the clinical signs of IA appear, but its sensitivity and specificity are variable. False-positivity is a significant disadvantage, and consecutive positive GM must be taken into account in the case of clinical and imaging findings that are relevant to IA. (C) 2016 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
Anahtar Kelimeler : Galactomannan, Aspergillosis, True-positive, False-positive, Children, Acute lymphoblastic leukemia, article
Cilt: 54
ISSN: 1201-9712
Sınıflandırma :
10
Tigecycline in the management of post-neurosurgical spondylodiscitis: a review of eight cases
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Sipahi Oguz Resat , Kahraman Hasip , Mermer Sinan , Pullukcu Husnu , Tasbakan Meltem , Arda Bilgin , Yamazhan Tansu , Yurtseven Taskin , Aydemir Sohret , Ulusoy Sercan
Konu :
Spondylitis, Nosocomial, Hospital-acquired, Healthcare-associated infection, Acinetobacter baumannii, Carbapenem-resistant
Yıl :
2014
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Background: Tigecycline is a relatively new glycylcycline antimicrobial, active in vitro against a variety of Gram-positive and Gram-negative organisms. In this study we evaluated the outcomes of spondylodiscitis cases treated with tigecycline-including therapies retrospectively. Methods: All adult (age > 18 years) cases with a diagnosis of spondylodiscitis, who were treated with a tigecycline-including therapy between 2007 and 2011, were included in the study. The primary efficacy outcome was clinical success with tigecycline at the end of induction, while the secondary efficacy outcome was maintenance of success through 3 months following completion of induction. Results: A total of eight spondylodiscitis cases fulfilled the study inclusion criteria. All cases had back pain, restricted mobility, magnetic resonance findings associated with spondylodiscitis, and microbiology or pathological findings related to spondylodiscitis. All had post-neurosurgical spondylodiscitis. In five cases, tigecycline was started in accordance with the antibacterial susceptibility results from intervertebral tissue biopsy cultures, whereas in three it was started empirically. All cases had received several different antibacterials with failure before receiving tigecycline. The mean duration of tigecycline treatment was 37 +/- 21 days. One case was lost to follow-up after 2 days of tigecycline. Primary and secondary success was achieved in the remaining seven cases. Conclusions: These limited data suggest that tigecycline may have a role in the treatment of refractory spondylodiscitis cases. (C) 2014 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
Anahtar Kelimeler : Spondylitis, Nosocomial, Hospital-acquired, Healthcare-associated infection, Acinetobacter baumannii, Carbapenem-resistant, article
Cilt: 23
ISSN: 1201-9712
Sınıflandırma :
11
Response to letter to the editor re ‘HIV Trends: Defining “The Middle East’
Araştırma Makalesi

Araştırma Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier B.V.
Yazar(lar) :
Gökengin D. , Madani N.
Yıl :
2016
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : letter
Cilt: 48
ISSN: 1201-9712
12
Mortality indicators in community-acquired pneumonia requiring intensive care in Turkey
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Çukurova Üniversitesi
Yazar(lar) :
Erdem H. , Turkan H. , Cilli A. , Karakas A. , Karakurt Z. , Bilge U. , Yazicioglu-Mocin O.
Konu :
CAP, Community-acquired pneumonia, ICU, Intensive care unit, Outcome
Yıl :
2013
International Journal of Infectious Diseases
Piri Tam Metin Bulucu
Kaydet Alıntıla
Background: Severe community-acquired pneumonia (SCAP) is a fatal disease. This study was conducted to describe an outcome analysis of the intensive care units (ICUs) of Turkey. Methods: This study evaluated SCAP cases hospitalized in the ICUs of 19 different hospitals between October 2008 and January 2011. The cases of 413 patients admitted to the ICUs were retrospectively analyzed. Results: Overall 413 patients were included in the study and 129 (31.2%) died. It was found that bilateral pulmonary involvement (odds ratio (OR) 2.5, 95% confidence interval (CI) 1.1-5.7) and CAP PIRO score (OR 2, 95% CI 1.3-2.9) were independent risk factors for a higher in-ICU mortality, while arterial hypertension (OR 0.3, 95% CI 0.1-0.9) and the application of non-invasive ventilation (OR 0.2, 95% CI 0.1-0.5) decreased mortality. No culture of any kind was obtained for 90 (22%) patients during the entire course of the hospitalization. Blood, bronchoalveolar lavage, and non-bronchoscopic lavage cultures yielded enteric Gram-negatives (n=12), followed by Staphylococcus aureus (n=10), pneumococci (n=6), and Pseudomonas aeruginosa (n=6). For 22% of the patients, none of the culture methods were applied. Conclusions: SCAP requiring ICU admission is associated with considerable mortality for ICU patients. Increased awareness appears essential for the microbiological diagnosis of this disease. © 2013 International Society for Infectious Diseases.
DOI : 10.1016/j.ijid.2013.03.015
Anahtar Kelimeler : CAP, Community-acquired pneumonia, ICU, Intensive care unit, Outcome, article
Cilt: 17
Sayı: 9
ISSN: 1201-9712
Sınıflandırma :
13
Mortality indicators in pneumococcal meningitis: therapeutic implications
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Hakan Erdem , Nazif Elaldi , Nefise Oztoprak , Gonul Sengoz , Oznur Ak , Selcuk Kaya , Haluk Vahaboglu
Konu :
Streptococcus pneumoniae, Meningitis, Mortality, Penicillin, Resistance, Vancomycin
Yıl :
2014
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Background: the aim of this study was to delineate mortality indicators in pneumococcal meningitis with special emphasis on therapeutic implications. Methods: This retrospective, multicenter cohort study involved a 15-year period (1998-2012). Culture-positive cases (n = 306) were included solely from 38 centers. Results: Fifty-eight patients received ceftriaxone plus vancomycin empirically. the rest were given a third-generation cephalosporin alone. Overall, 246 (79.1%) isolates were found to be penicillin-susceptible, 38 (12.2%) strains were penicillin-resistant, and 22 (7.1%) were oxacillin-resistant (without further minimum inhibitory concentration testing for penicillin). Being a critical case (odds ratio (OR) 7.089, 95% confidence interval (CI) 3.230-15.557) and age over 50 years (OR 3.908, 95% CI 1.820-8.390) were independent predictors of mortality, while infection with a penicillin-susceptible isolate (OR 0.441, 95% CI 0.195-0.996) was found to be protective. Empirical vancomycin use did not provide significant benefit (OR 2.159, 95% CI 0.949-4.912). Conclusions: Ceftriaxone alone is not adequate in the management of pneumococcal meningitis due to penicillin-resistant pneumococci, which is a major concern worldwide. Although vancomycin showed a trend towards improving the prognosis of pneumococcal meningitis, significant correlation in statistical terms could not be established in this study. Thus, further studies are needed for the optimization of pneumococcal meningitis treatment. (C) 2013 the Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. All rights reserved.
Anahtar Kelimeler : Streptococcus pneumoniae, Meningitis, Mortality, Penicillin, Resistance, Vancomycin, article
Cilt: 19
ISSN: 1201-9712
Sınıflandırma :
14
Crimean-Congo hemorrhagic fever in pregnancy: A systematic review and case series from Russia, Kazakhstan and Turkey
Araştırma Makalesi

Araştırma Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal Of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Natalia Yurievna Pshenichnaya , Hakan Leblebicioglu , Ilkay Bozkurt , Irina Viktorovna Sannikova , Gulzhan Narkenovna Abuova , Andrey Sergeevich Zhuravlev , Sener Barut
Konu :
Crimean-Congo hemorrhagic fever, pregnancy, healthcare associated infection, viral hemorrhagic fever
Yıl :
2017
International Journal Of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Background: Crimean-Congo hemorrhagic fever (CCHF) is acute viral infection and a major emerging infectious diseases threat, affecting a large geographical area. There is no proven antiviral therapy and it has a case fatality rate of 4-30%. The natural history of disease and outcomes of CCHF in pregnant women is poorly understood. Objectives: To systematically review the characteristics of CCHF in pregnancy, and report a case series of 8 CCHF cases in pregnant women from Russia, Kazakhstan and Turkey. Methods: A systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement protocol. PubMed, SCOPUS, Science Citation Index (SCI) were searched for reports published between January 1960 and June 2016. Two independent reviewers selected and reviewed studies and extracted data. Results: Thirty-four cases of CCHF in pregnancy were identified, and combined with the case series data, 42 cases were analyzed. The majority of cases originated in Turkey (14), Iran (10) and Russia (6). There was a maternal mortality of 14/41(34%) and fetal/neonatal mortality of in 24/41 cases (58.5%). Hemorrhage was associated with maternal (p = 0.009) and fetal/neonatal death (p < 0.0001). There was nosocomial transmission to 38 cases from 6/37 index pregnant cases. Conclusion: Cases of CCHF in pregnancy are rare, but associated with high rates of maternal and fetal mortality, and nosocomial transmission. (C) 2017 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
Anahtar Kelimeler : Crimean-Congo hemorrhagic fever, pregnancy, healthcare associated infection, viral hemorrhagic fever, review
Cilt: 58
ISSN: 1201-9712
15
Influence of multidrug resistant organisms on the outcome of diabetic foot infection
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
International Journal of Infectious Diseases
Yazar(lar) :
N. Saltoglu , O. Ergonul , N. Tulek , M. Yemisen , A. Kadanali , G. Karagoz , Group Diabetic Foot Infections Study
Konu :
Diabetic foot infection, Fatality, Klebsiella, MRSA
Yıl :
2018
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Objectives: We described the clinical outcomes of the diabetic patients who had foot infections with multidrug resistant organisms. Methods: We included the patients with diabetic foot infections (DFI) from 19 centers, between May 2011 and December 2015. Infection was defined according to IDSA DFI guidelines. Patients with severe infection, complicated moderate infection were hospitalized. The patients were followed-up for 6 months after discharge. Results: In total, 791 patients with DFI were included, 531(67%) were male, median age was 62 (19–90). Severe infection was diagnosed in 85 (11%) patients. Osteomyelitis was diagnosed in 291(36.8%) patients. 536 microorganisms were isolated, the most common microorganisms were S. aureus (20%), P. aeruginosa (19%) and E. coli (12%). Methicillin resistance (MR) rate among Staphylococcus aureus isolates was 31%. Multidrug resistant bacteria were detected in 21% of P. aeruginosa isolates. ESBL (+) Gram negative bacteria (GNB) was detected in 38% of E. coli and Klebsiella isolates. Sixty three patients (8%) were re-hospitalized. Of the 791 patiens, 127 (16%) had major amputation, and 24 (3%) patients died. In multivariate analysis, significant predictors for fatality were; dialysis (OR: 8.3, CI: 1.82–38.15, p = 0.006), isolation of Klebsiella spp. (OR:7.7, CI: 1.24–47.96, p = 0.028), and chronic heart failure (OR: 3, CI: 1.01–9.04, p = 0.05). MR Staphylococcus was detected in 21% of the rehospitalized patients, as the most common microorganism (p < 0.001). Conclusion: Among rehospitalized patients, methicillin resistant Staphylococcus infections was detected as the most common agent, and Klebsiella spp. infections were found to be significantly associated with fatality. © 2018 The Authors
Anahtar Kelimeler : Diabetic foot infection, Fatality, Klebsiella, MRSA, article

ISSN: 12019712
16
Detection Mycoplasma hyopneumoniae in pigs in Turkey
Bildiri Serisi

Bildiri Serisi
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yazar(lar) :
SERKAN İKİZ , ARZU FUNDA BAĞCIGİL , NACIYE YAKUT ÖZGÜR
Konu :
Yaşam Bilimleri, Temel Bilimler, Mikrobiyoloji, Yaşam Bilimleri (LIFE)
Yıl :
2021
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : Yaşam Bilimleri, Temel Bilimler, Mikrobiyoloji, Yaşam Bilimleri (LIFE), Bildiri
Sınıflandırma :
17
Wallach'ın Tanıda Laboratuvar Testlerinin Yorumlanması
Kitap Bölümü

Kitap Bölümü
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yazar(lar) :
Zeliha Emel ZENGİN
Konu :
Sağlık Bilimleri, Tıp, Klinik Tıp (MED)
Yıl :
2021
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : Sağlık Bilimleri, Tıp, Klinik Tıp (MED), Kitapta Bölüm
Sınıflandırma :
18
SARS-CoV2 Genomu ile Diğer Viral Genomların Kıyaslanması
Bildiri Serisi

Bildiri Serisi
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yazar(lar) :
Gözde Öztan
Konu :
Tıbbi Genetik, Genetics, Genetics (clinical), Life Sciences, Health Sciences, BİYOLOJİ, Klinik Tıp (MED), Yaşam Bilimleri (LIFE), Klinik Tıp, Biyoloji ve Biyokimya, Moleküler Biyoloji ve Genetik, GENETİK VE HAYAT, Tıp, Sağlık Bilimleri, Tıbbi Biyoloji
Yıl :
2021
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : Tıbbi Genetik, Genetics, Genetics (clinical), Life Sciences, Health Sciences, BİYOLOJİ, Klinik Tıp (MED), Yaşam Bilimleri (LIFE), Klinik Tıp, Biyoloji ve Biyokimya, Moleküler Biyoloji ve Genetik, GENETİK VE HAYAT, Tıp, Sağlık Bilimleri, Tıbbi Biyoloji, Bildiri
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Biyotıp %100
19
Molecular Gastronomy is a Scientific Discipline, and Note by Note Cuisine is The Next Culinary Trend (Herve This), (Çeviri: Moleküler Gastronomi Bilimsel Bir Disiplin, NbN Mutfak Bir Sonraki Mutfak Eğilimidir), Anatolia: Turizm Araştırmaları Dergisi, Cilt 28, Sayı 2
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yazar(lar) :
Şehnaz DEMİRKOL , İbrahim ÇİFÇİ
Konu :
Sosyal ve Beşeri Bilimler, Sosyal Bilimler Genel, Sosyal Bilimler (SOC)
Yıl :
2021
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
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Tam Metin
Kaydet Alıntıla
Anahtar Kelimeler : Sosyal ve Beşeri Bilimler, Sosyal Bilimler Genel, Sosyal Bilimler (SOC), Diğer Yayınlar
Sınıflandırma :
20
Rutin anomali taramasında nelere baklamıyız? Hangi anomaliler atlanmamalı?
Bildiri Serisi

Bildiri Serisi
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yazar(lar) :
Atıl YÜKSEL
Konu :
Tıp, Sağlık Bilimleri, Klinik Tıp (MED)
Yıl :
2021
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : Tıp, Sağlık Bilimleri, Klinik Tıp (MED), Bildiri
Sınıflandırma :
21
Case report: A rarely seen cause of brain abscess - neurotoxocariasis
Konferans Makalesi

Konferans Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Sipahi O. R. , Kivrak E. Erdem , Korkmaz M. , Tasbakan M. , Pullukcu H. , Arda B. , Yamazhan T. , Ulusoy S.
Yıl :
2014
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Anahtar Kelimeler : conferenceObject
Cilt: 21
ISSN: 1201-9712
Sınıflandırma :
22
Effectiveness of a new bioequivalent formulation of oseltamivir (Enfluvir ®) on 2010-2011 seasonal influenza viruses: An open phase IV study
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Ege Universitesi
Yazar(lar) :
Ceyhan M. , Karadag Oncel E. , Badur S. , Ciblak M.A. , Alhan E. , Celik U.S. , Kurugol Z. , Saz E.U. , Ozsurekci Y. , Celik M. , Parlakay A.O.
Konu :
Children, Influenza, Oseltamivir, Symptom duration
Yıl :
2012
International Journal of Infectious Diseases
Kaydet Alıntıla
Objective: The aim of this multicenter prospective study was to evaluate the efficacy of a new bioequivalent formulation of oseltamivir for the treatment of influenza A, influenza B, and H1N1 during the 2010-2011 influenza season. Methods: We compared the symptoms and signs of 300 pediatric patients presenting to three university hospitals with an influenza-like illness between January and March 2011. Nasal swab specimens were collected from all children and tested by reverse-transcription polymerase chain reaction (RT-PCR) for influenza viruses. After randomization, half of the participants were prescribed oseltamivir, while the other half were observed conservatively. Forty patients who were followed-up for influenza prior to the study were also included in the evaluation. Results: Influenza was confirmed by RT-PCR in 129 children, 71 of whom were prescribed oseltamivir. The durations of the symptoms fever, cough, nasal congestion, and rhinorrhea were significantly shorter for patients who were treated with oseltamivir compared with untreated patients (. p<. 0.002 for all symptoms). Early initiation of oseltamivir therapy (within 48. h of the onset of symptoms) was associated with more favorable outcomes and an earlier recovery than in patients for whom treatment was delayed (beyond 48. h). Thirty-seven patients (28.7%) had H1N1, 44 (34.1%) had influenza A, 46 (35.7%) had influenza B, one (0.8%) had H1N1 plus influenza A, and one (0.8%) had influenza A plus influenza B viruses. In the comparison of the duration of symptoms according to the different virus types, a statistically significant difference was only observed in patients with influenza B who had a longer duration of cough (. p<. 0.001), nasal congestion (. p<. 0.001), and rhinorrhea (. p<. 0.001). Conclusions: Oseltamivir is an effective treatment for the management of seasonal influenza and H1N1, and should be initiated immediately without waiting for laboratory confirmation of diagnosis. © 2012 International Society for Infectious Diseases.
Anahtar Kelimeler : Children, Influenza, Oseltamivir, Symptom duration, article
Cilt: 16
Sayı: 4
ISSN: 1201-9712
23
HIV care in times of the COVID-19 crisis — Where are we now in Central and Eastern Europe?
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier B.V.
Yazar(lar) :
Ege Universitesi
Konu :
ARV, COVID-19, HIV, SARS-CoV-2
Yıl :
2020
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Kaydet Alıntıla
Introduction: The SARS-CoV-2 pandemic has hit the European region disproportionately. Many HIV clinics share staff and logistics with infectious disease facilities, which are now on the frontline in tackling COVID-19. Therefore, this study investigated the impact of the current pandemic situation on HIV care and continuity of antiretroviral treatment (ART) supplies in CEE countries. Methods: The Euroguidelines in Central and Eastern Europe (ECEE) Network Group was established in February 2016 to review standards of care for HIV in the region. The group consists of professionals actively involved in HIV care. On March 19, 2020 we decided to review the status of HIV care sustainability in the face of the emerging SARS-CoV-2 pandemic in Europe. For this purpose, we constructed an online survey consisting of 23 questions. Respondents were recruited from ECEE members in 22 countries, based on their involvement in HIV care, and contacted via email. Results: In total, 19 countries responded: Albania, Armenia, Belarus, Bosnia and Herzegovina, Bulgaria, Croatia, Czech Republic, Estonia, Georgia, Greece, Hungary, Lithuania, Macedonia, Poland, Republic of Moldova, Russia, Serbia, Turkey, and Ukraine. Most of the respondents were infectious disease physicians directly involved in HIV care (17/19). No country reported HIV clinic closures. HIV clinics were operating normally in only six countries (31.6%). In 11 countries (57.9%) physicians were sharing HIV and COVID-19 care duties. None of the countries expected shortage of ART in the following 2 weeks; however, five physicians expressed uncertainty about the following 2 months. At the time of providing responses, ten countries (52.6%) had HIV-positive persons under quarantine. Conclusions: A shortage of resources is evident, with an impact on HIV care inevitable. We need to prepare to operate with minimal medical resources, with the aim of securing constant supplies of ART. Non-governmental organizations should re-evaluate their earlier objectives and support efforts to ensure continuity of ART delivery. © 2020 The Authors
Anahtar Kelimeler : ARV, COVID-19, HIV, SARS-CoV-2, article
Cilt: 96
ISSN: 1201-9712
Sınıflandırma :
24
Hepatitis delta virus (HDV) genotypes in patients with chronic hepatitis: molecular epidemiology of HDV in Turkey
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier Sci Ltd
Yazar(lar) :
Altuglu Imre , Ozacar Tijen , Sertoz Ruchan Yazan , Erensoy Selda
Konu :
genotype, hepatitis delta virus, sequencing
Yıl :
2007
International Journal of Infectious Diseases
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Kaydet Alıntıla
Objective: Analysis of hepatitis delta virus (HDV) isolates from around the world has indicated that there are at least three phylogenetically distinct genotypes with different geographic distributions. The aim of this study was to determine the distribution of HDV genotypes by direct sequencing in patients with chronic delta hepatitis in Izmir, Turkey. Design and methods: Serum samples from 32 chronic hepatitis patients (21 mates, 11 females; mean age 44.2 years, range 23-70 years) with anti-delta positivity were analyzed for hepatitis B and C serologies. After reverse transcription, cDNA of partial delta antigen was amplified by in-house nested PCR. The products of the HDV PCR were bidirectionally sequenced with internal primers using Big Dye Terminator DNA Sequencing Kit (Applied Biosystems, CA, USA) and ABI Prism 310 Genetic Analyzer (Perkin Elmer, USA). Nucteotide sequences of HDV were compared with previously reported sequences and aligned by using ClustalW (1.82). Results: HDV-RNA was positive in 26 (81.3%) of 32 anti-delta positive samples. Comparison of the HDVsequences with published sequences of HDV genotypes 1, 11, and III indicated that all were closely related to HDV genotype I isolates. Similarity among isolated sequences ranged from 84% to 96%. Conclusion: HDV genotyping was successfully performed by direct sequencing of the amplicons obtained from routine HDV-RNA screening PCR tests. All of the HDV isolates from the chronic delta hepatitis patients included in this study were found to be genotype I. (c) 2006 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Anahtar Kelimeler : genotype, hepatitis delta virus, sequencing, article
Cilt: 11
Sayı: 1
ISSN: 1201-9712
Sınıflandırma :
Viroloji %100
25
Community acquired infections among refugees leading to Intensive Care Unit admissions in Turkey
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
Elsevier B.V.
Yazar(lar) :
Turktan M. , Ak O. , Erdem H. , Ozcengiz D. , Hargreaves S. , Kaya S. , Karakoc E.
Konu :
community-acquired infections, intensive-care unit, refugees, Syria, Turkey
Yıl :
2017
International Journal of Infectious Diseases
Yayıncı Web Sitesi
 Piri Tam Metin Bulucu
Kaydet Alıntıla
Objectives Data on the impact of refugees on Intensive Care Units (ICUs) are lacking in the literature, in particular for community-acquired (CA) infectious diseases, for which they are known to be at higher risk. We did a descriptive, multicenter study to analyze CA infections among refugee patients requiring ICU admission. Methods Inclusion criteria were adult refugee patients admitted to an ICU due to CA infections. Anonymized data were collected between January 1, 2010 and December 30, 2015 across 10 referral centers. Results 29.885 patients were admitted to the ICUs in the study period. 37 patients were included the study, the majority were from Syria (n = 31, 83.8%). Mean (SD) age of the patients was 45.92 ± 20.16 years. The 5-year prevalence rate was 123.8 per 100.000 patients in the ICUs. All patients had at least one comorbid condition. Forty-nine CA infections were diagnosed. The most common CA infection was pneumonia (49%) followed by urinary-tract infections (16.3%). 21 patients (56.7%) hospitalized in the ICU had trauma history. Mortality rate was high at 22 patients (59.5%) with 5 (22.7%) deaths directly attributed to CA infections. Conclusions Refugees presented to ICUs with CA infections similar to the host populations (pneumonia and urinary-tract infections) but had high mortality rates (59.5%). It seems that Turkish ICUs were not congested with the refugee patients’ influx for CA infections. More research needs to be done to better understand how to deliver preventative and timely health care services to this group of patients. © 2017 International Society for Infectious Diseases
DOI : 10.1016/j.ijid.2017.02.022
Anahtar Kelimeler : community-acquired infections, intensive-care unit, refugees, Syria, Turkey, article
Cilt: 58
ISSN: 1201-9712
Sınıflandırma :
26
Serotype distribution and antibiotic resistance among isolates of streptococcus pneumoniae causing invasive pneumococcal disease in adults in Turkey: 2005-2015
Konferans Makalesi

Konferans Makalesi
Kaynak :
DSpace Makaleler
Dergi:
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı:
ELSEVIER SCI LTD
Yazar(lar) :
Hascelik , G. , Gurler , N. , Ceyhan , M. , Ozakin , C. , Bayramoglu , G. , Gulay , Z. , Soyletir , G.
Yıl :
2016
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Yayıncı Web Sitesi
Kaydet Alıntıla
DOI : 10.1016/j.ijid.2016.02.243
Anahtar Kelimeler : conferenceObject
Cilt: 45
ISSN: 1201-9712
Sınıflandırma :
27
Detection of crimean-congo hemorrhagic fever virus genome in saliva and urine
Dergi Makalesi

Dergi Makalesi
Open Access
Kaynak :
DSpace Makaleler
Dergi:
International Journal of Infectious Diseases
Yayıncı:
International Journal of Infectious Diseases
Yazar(lar) :
Hürrem Bodur , Esragül Akıncı , Pınar Öngürü , Ahmet Çarhan , Yavuz Uyar , Aliye Tanrıcı , Osman Çataloluk , Ayhan Kubar
Konu :
Crimean-Congo Hemorrhagic Fever, Saliva, Urine
Yıl :
2010
International Journal of Infectious Diseases
Yayıncı Web Sitesi
Tam Metin
Kaydet Alıntıla
Çataloluk, Osman (Balikesir Author) Background: The Crimean-Congo hemorrhagic fever (CCHF) virus is transmitted by tick bites and by contact with the blood or tissues of infected patients and livestock. This study was designed to investigate the genome of CCHF virus in saliva and urine samples of patients with CCHF. Methods: Eight patients with laboratory-confirmed CCHF were included in the study. The diagnosis was made by detection of viral RNA in blood by real-time reverse transcriptase-polymerase chain reaction (real-time RT-PCR). Samples of saliva from six patients and samples of urine from three patients were collected at the same time as the blood samples and analyzed for viral RNA. Results: The genome of CCHF virus was detected in the saliva from five of the six patients and in the urine from two of the three patients. The levels of viral load in the saliva and urine samples were similar to those in the blood samples in all but one patient, in whom higher levels were detected in blood compared to saliva or urine. Conclusions: This study shows that during human infection with CCHF virus, viral genomes are present in the saliva and urine. Further studies to isolate infectious viruses from these fluids and to study whether they represent an infectious risk are underway.
Anahtar Kelimeler : Crimean-Congo Hemorrhagic Fever, Saliva, Urine, article

ISSN: 1201-9712

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