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Total Dietary Antioxidant Intake Including Polyphenol Content: Is It Capable to Fight against Increased Oxidants within the Body of Ultra-Endurance Athletes?
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
NUTRIENTS
Yazar(lar) :
Asli Devrim-Lanpir , Pelin Bilgic , Tugba Kocahan , Gokhan Deliceoglu , Thomas Rosemann , Beat Knechtle
Konu :
ultra-endurance, dietary antioxidants, total antioxidant capacity, exercise intensity, post-exercise recovery, 8-iso prostaglandin F2a
Yıl :
2020
NUTRIENTS
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The role of dietary antioxidants on exhaustive exercise-induced oxidative stress has been well investigated. However, the contribution of total dietary antioxidant capacity on exogenous antioxidant defense and exercise performance has commonly been disregarded. The aims of the present investigation were to examine (i) the effects of dietary total antioxidant intake on body antioxidant mechanisms, and (ii) an exhaustive exercise-induced oxidative damage in ultra-endurance athletes. The study included 24 ultra-marathon runners and long-distance triathletes (12 male and 12 female) who underwent an acute exhaustive exercise test (a cycle ergometer (45 min at 65% VO(2)max) immediately followed by a treadmill test (75% VO(2)max to exhaustion). Oxidative stress-related biomarkers (8-isoprostaglandin F2alpha (8-iso PGF2a), total oxidant status (TOS, total antioxidant status (TAS)) in plasma were collected before and after exercise. Oxidative stress index was calculated to assess the aspect of redox balance. Blood lactate concentrations and heart rate were measured at the 3rd and 6th min after exercise. Dietary antioxidant intake was calculated using the ferric reducing ability of plasma (FRAP) assay. Dietary total antioxidant intake of the subjects was negatively correlated with pre-exercise TOS concentrations (rs = -0.641 in male, and rs = -0.741 in females) and post- vs. pre- ( increment ) 8-iso PGF2a levels (rs = -0.702 in male;p= 0.016, and rs = -0.682 in females;p= 0.024), and positively correlated with increment TAS concentrations (rs = 0.893 in males;p= 0.001, and rs = 0.769 in females;p= 0.002) and post- exercise lactate concentrations (rs = 0.795 for males;p= 0.006, and rs = 0.642 for females;p= 0.024). A positive meaningful (p= 0.013) interaction was observed between time at exhaustion and dietary antioxidant intake (rs = 0.692) in males, but not in females. In conclusion, the determination of total dietary antioxidant intake in ultra-endurance athletes may be crucial for gaining a better perspective on body antioxidant defense against exhaustive exercise-induced oxidative stress. However, the effects of dietary antioxidant on exercise performance and recovery rate needs further investigation.
DOI : 10.3390/nu12061877
Anahtar Kelimeler : ultra-endurance, dietary antioxidants, total antioxidant capacity, exercise intensity, post-exercise recovery, 8-iso prostaglandin F2a, article
Cilt: 12
Sayı: 6
ISSN: 2072-6643
Sınıflandırma :
2
Dietary sources of high sodium intake in Turkey: SALTURK II
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
Nutrients
Yayıncı:
Gazi Üniversitesi
Yazar(lar) :
Y. Erdem , T. Akpolat , Ü. Derici , Ş. Şengül , Ş. Ertürk , Ş. Ulusoy , B. Altun , M. Arıcı
Yıl :
2017
Nutrients
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Kaydet Alıntıla
DOI : 10.3390/nu9090933
Anahtar Kelimeler : Article
Cilt: 9
Sayı: 9
Sınıflandırma :
3
Effects of Regular Kefir Consumption on Gut Microbiota in Patients with Metabolic Syndrome: A Parallel-Group, Randomized, Controlled Study
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Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
Nutrients
Yazar(lar) :
Bellikci-Koyu Ezgi , Sarer-Yurekli Banu Pinar , Akyon Yakut , Aydin-Kose Fadime , Karagozlu Cem , Ozgen Ahmet Gokhan , Buyuktuncer Zehra
Konu :
kefir, gut microbiota, metabolic syndrome
Yıl :
2019
Nutrients
Kaydet Alıntıla
Several health-promoting effects of kefir have been suggested, however, there is limited evidence for its potential effect on gut microbiota in metabolic syndrome This study aimed to investigate the effects of regular kefir consumption on gut microbiota composition, and their relation with the components of metabolic syndrome. in a parallel-group, randomized, controlled clinical trial setting, patients with metabolic syndrome were randomized to receive 180 mL/day kefir (n = 12) or unfermented milk (n = 10) for 12 weeks. Anthropometrical measurements, blood samples, blood pressure measurements, and fecal samples were taken at the beginning and end of the study. Fasting insulin, HOMA-IR, TNF-alpha, IFN-gamma, and systolic and diastolic blood pressure showed a significant decrease by the intervention of kefir (p <= 0.05, for each). However, no significant difference was obtained between the kefir and unfermented milk groups (p > 0.05 for each). Gut microbiota analysis showed that regular kefir consumption resulted in a significant increase only in the relative abundance of Actinobacteria (p = 0.023). No significant change in the relative abundance of Bacteroidetes, Proteobacteria or Verrucomicrobia by kefir consumption was obtained. Furthermore, the changes in the relative abundance of sub-phylum bacterial populations did not differ significantly between the groups (p > 0.05, for each). Kefir supplementation had favorable effects on some of the metabolic syndrome parameters, however, further investigation is needed to understand its effect on gut microbiota composition.
Anahtar Kelimeler : kefir, gut microbiota, metabolic syndrome, article
Cilt: 11
Sayı: 9
ISSN: 2072-6643
4
Almonds (Prunus dulcis Mill. D. A. webb): A source of nutrients and health-promoting compounds
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
Nutrients
Yayıncı:
Gazi Üniversitesi
Yazar(lar) :
D. and Nabavi Barreca
Yıl :
2020
Nutrients
Yayıncı Web Sitesi
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Kaydet Alıntıla
DOI : 10.3390/nu12030672
Cilt: 12
Sayı: 3
Sınıflandırma :
5
Maternal Low Quality Protein Diet Alters Plasma Amino Acid Concentrations of Weaning Rats
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Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
Nutrients
Yazar(lar) :
Arzu Kabasakal Cetin , Halil Dasgin , Atila Gulec , Ilyas Onbasilar , Asli Akyol
Konu :
fetal programming, low quality protein, pregnancy, rats
Yıl :
2015
Nutrients
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Kaydet Alıntıla
Several studies have indicated the influence of a maternal low protein diet on the fetus. However, the effect of a maternal low quality protein diet on fetal growth and development is largely unknown. Wistar rats (11 weeks old) were mated and maintained on either a chow diet with 20% casein (n = 6) as the control group (C), or a low quality protein diet with 20% wheat gluten (n = 7) as the experimental group (WG) through gestation and lactation. Maternal body weights were similar in both groups throughout the study. Birth weights were not influenced by maternal diet and offspring body weights during lactation were similar between the groups. Offspring's plasma amino acid profiles showed that plasma methionine, glutamine and lysine were significantly lower and aspartic acid, ornithine and glycine-proline were significantly higher in the WG. Plant based protein comprises an important part of protein intake in developing countries. It is well-known that these diets can be inadequate in terms of essential amino acids. The current study shows differential effects of a maternal low quality protein diet on the offspring's plasma amino acids. Future studies will examine further aspects of the influence of maternal low quality protein diets on fetal growth and development.
DOI : 10.3390/nu7125508
Anahtar Kelimeler : fetal programming, low quality protein, pregnancy, rats, article
Cilt: 7
Sayı: 12
ISSN: 2072-6643
Sınıflandırma :
6
beta-Glucan and Dark Chocolate: A Randomized Crossover Study on Short-Term Satiety and Energy Intake
Dergi Makalesi

Dergi Makalesi
Kaynak :
DSpace Makaleler
Dergi:
Nutrients
Yazar(lar) :
Asli Akyol , Halil Dasgin , Aylin Ayaz , Zehra Buyuktuncer , H. Tanju Besler
Konu :
-glucan, dark chocolate, satiety
Yıl :
2014
Nutrients
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 Piri Tam Metin Bulucu
Kaydet Alıntıla
Aim: The aims of this study were to adapt a traditional recipe into a healthier form by adding 3 g of oat -glucan, substituting milk chocolate to dark chocolate with 70% cocoa, and to examine the effect of these alterations on short-term satiety and energy intake. Materials and Methods: Study subjects (n = 25) were tested in a randomized, crossover design with four products closely matched for energy content. Four different versions of a traditional recipe including milk chocolate-control (CON), oat -glucan (B-GLU), dark chocolate (DARK) or oat -glucan and dark chocolate (B-GLU + DARK) were given to subjects on different test days. After subjects were asked to report visual analog scale (VAS) scores on sensory outcomes and related satiety for four hours ad libitum, lunch was served and energy intake of individuals was measured. Results: VAS scores indicated that none of the test foods exerted an improved effect on satiety feelings. However, energy intake of individuals during ad libitum lunch was significantly lower in dark chocolate groups (CON: 849.46 +/- 47.45 kcal versus DARK: 677.69 +/- 48.45 kcal and B-GLU + DARK: 691.08 +/- 47.45 kcal, p = 0.014). Conclusion: The study demonstrated that substituting dark chocolate for milk chocolate is more effective in inducing satiety during subsequent food intake in healthy subjects.
DOI : 10.3390/nu6093863
Anahtar Kelimeler : -glucan, dark chocolate, satiety, article
Cilt: 6
Sayı: 9
ISSN: 2072-6643
Sınıflandırma :
Kimya %100
Yemek Bilimi %100
7
Food Advertising and Prevention of Childhood Obesity in Spain: Analysis of the Nutritional Value of the Products and Discursive Strategies Used in the Ads Most Viewed by Children from 2016 to 2018
Dergi Makalesi

Dergi Makalesi
Kaynak :
RECERCAT
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Montaña Blasco Mireia , Jiménez-Morales Mònika , Vàzquez Garcia Mercè
Konu :
Advertising, Childhood obesity, Food, Health policy, Language, Nutrient profiling, Television, Advertising and children, Obesity in children, Publicitat--Aliments, Obesitat en els infants, Publicidad y niños, Obesidad en niños
Yıl :
2019
Nutrients
Yayıncı Web Sitesi
Kaydet Alıntıla
In Spain, 40% of children are overweight or obese. Television advertising is a widely acknowledged factor contributing to high-calorie food intake. This study longitudinally correlates some variables involved in childhood obesity prevention strategies in Spain. A mixed-methods approach was used. A quantitative analysis of audience data was conducted to determine the advertising campaigns most viewed by Spanish children from 2016 to 2018. The Nutri-score system was applied to determine the nutritional quality of the food advertised. A content analysis and a study of the discursive strategies used as an advertising ploy was undertaken. The results were examined in relation to the regulatory framework of the Spanish PAOS Code for the co-regulation of food advertising aimed at children. The study shows that Spanish advertising aimed at children mostly advertises very low nutritional value products. Moreover, these campaigns violate the PAOS Code in terms of the use of language in relation to the product, its benefits, and the appearance of popular characters. Our findings suggest a direct association between low nutritional value food ads and discursive strategies based on the intangible and extrinsic characteristics of these products. There remains the need for stricter legislation that takes into consideration the nutritional value of advertised foods and the language used in their hedonistic advertising.
Anahtar Kelimeler : Advertising, Childhood obesity, Food, Health policy, Language, Nutrient profiling, Television, Advertising and children, Obesity in children, Publicitat--Aliments, Obesitat en els infants, Publicidad y niños, Obesidad en niños
Tez türü: article
Sınıflandırma :
8
Body Mass Index (BMI) Trajectories from Birth to 11.5 Years: Relation to Early Life Food Intake.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Karen L Webb , Judy M Simpson , Guy B Marks , Frances L Garden
Yıl :
2012
Nutrients
Yayıncı Web Sitesi
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Kaydet Alıntıla
This article is from Nutrients, volume 4. Abstract Recent research has shown that the pattern of change over time, or trajectory, of body mass index (BMI) varies among children. However, the factors that underlie the heterogeneity in these trajectories remain largely unexplored. Our aim was to use a growth mixture model to empirically identify classes of BMI trajectories (from birth to 11.5 years) and examine the effects of breastfeeding, introduction of solids, as well as food and nutrient intake at 18 months on these BMI trajectories. We identified three BMI growth trajectories between birth and age 11.5 years, separately in boys and girls. Breastfeeding duration less than six months and the early introduction of solids did not adversely influence BMI trajectories in our sample but high intakes of meat, particularly high fat varieties, and high intakes of carbohydrate at age around 18 months were associated with a high BMI trajectory in boys. It is not clear whether these dietary factors confer a direct risk of higher BMI in childhood or are markers for other dietary patterns that are present early and/or develop through childhood and contribute to higher BMI.
DOI : doi:10.3390/nu4101382
Cilt :4
ISSN :2072-6643
Sınıflandırma :
9
Changes in Intakes of Total and Added Sugar and their Contribution to Energy Intake in the U.S.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Won O Song , Andrea Padgitt , Ying Wang , Chin E Chung , Ock K Chun
Yıl :
2010
Nutrients
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This article is from Nutrients, volume 2. Abstract This study was designed to document changes in total sugar intake and intake of added sugars, in the context of total energy intake and intake of nutrient categories, between the 1970s and the 1990s, and to identify major food sources contributing to those changes in intake. Data from the NHANES I and III were analyzed to obtain nationally representative information on food consumption for the civilian, non-institutionalized population of the U.S. from 1971 to 1994. In the past three decades, in addition to the increase in mean intakes of total energy, total sugar, added sugars, significant increases in the total intake of carbohydrates and the proportion of carbohydrates to the total energy intake were observed. The contribution of sugars to total carbohydrate intake decreased in both 1–18 y and 19+ y age subgroups, and the contribution of added sugars to the total energy intake did not change. Soft drinks/fluid milk/sugars and cakes, pastries, and pies remained the major food sources for intake of total sugar, total carbohydrates, and total energy during the past three decades. Carbonated soft drinks were the most significant sugar source across the entire three decades. Changes in sugar consumption over the past three decades may be a useful specific area of investigation in examining the effect of dietary patterns on chronic diseases.
DOI : doi:10.3390/nu2080834
Cilt :2
ISSN :2072-6643
Sınıflandırma :
10
Consumption of a Diet Rich in Cottonseed Oil (CSO) Lowers Total and LDL Cholesterol in Normo-Cholesterolemic Subjects.
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Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Victorine Imrhan , Chandan Prasad , Kathleen E Davis
Yıl :
2012
Nutrients
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This article is from Nutrients, volume 4. Abstract Animal data indicates that dietary cottonseed oil (CSO) may lower cholesterol; however, the effects of a CSO-rich diet have not been evaluated in humans. Thirty-eight healthy adults (aged 18%#x2013;40; 12 males, 26 females) consumed a CSO rich diet (95 g CSO daily) for one week. Anthropometric measurements were obtained, and blood was drawn pre- and post-intervention. Serum lipids (total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG), and free fatty acids (FFA)) were assayed. There was no change in weight or waist circumference among participants. There was no change in HDL (Pre: 1.27 ± 0.4 mmol/L; Post: 1.21 ± 0.3 mmol/L) or TG (Pre: 0.91 ± 0.6 mmol/L; Post: 1.06 ± 1.0 mmol/L). Total cholesterol and LDL were reduced (TC Pre: 4.39 ± 0.9 mmol/L; Post: 4.16 ± 0.8 mmol/L; LDL Pre: 2.70 ± 0.8 mmol/L; Post: 2.47 ± 0.6 mmol/L). When data were grouped by sex, total cholesterol was reduced in female participants (Pre: 4.34 ± 0.9 mmol/L; Post: 4.09 ± 0.8 mmol/L). Consumption of a high fat, CSO-rich diet for one week reduced total cholesterol in female participants without reducing HDL.
DOI : doi:10.3390/nu4070602
Cilt :4
ISSN :2072-6643
Sınıflandırma :
11
A Novel Role for a Major Component of the Vitamin D Axis: Vitamin D Binding Protein-Derived Macrophage Activating Factor Induces Human Breast Cancer Cell Apoptosis through Stimulation of Macrophages.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Stefania Pacini , Marco Ruggiero , Massimo Gulisano , Gabriele Morucci , Jacopo J V Branca , Stefano Magherini , Maria Giulia Fiore , Rodney Smith , Emma Ward , Lynda Thyer
Yıl :
2013
Nutrients
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This article is from Nutrients, volume 5. Abstract The role of vitamin D in maintaining health appears greater than originally thought, and the concept of the vitamin D axis underlines the complexity of the biological events controlled by biologically active vitamin D (1,25(OH)(2)D3), its two binding proteins that are the vitamin D receptor (VDR) and the vitamin D-binding protein-derived macrophage activating factor (GcMAF). In this study we demonstrate that GcMAF stimulates macrophages, which in turn attack human breast cancer cells, induce their apoptosis and eventually phagocytize them. These results are consistent with the observation that macrophages infiltrated implanted tumors in mice after GcMAF injections. In addition, we hypothesize that the last 23 hydrophobic amino acids of VDR, located at the inner part of the plasma membrane, interact with the first 23 hydrophobic amino acids of the GcMAF located at the external part of the plasma membrane. This al1ows 1,25(OH)(2)D3 and oleic acid to become sandwiched between the two vitamin D-binding proteins, thus postulating a novel molecular mode of interaction between GcMAF and VDR. Taken together, these results support and reinforce the hypothesis that GcMAF has multiple biological activities that could be responsible for its anti-cancer effects, possibly through molecular interaction with the VDR that in turn is responsible for a multitude of non-genomic as well as genomic effects.
DOI : doi:10.3390/nu5072577
Cilt :5
ISSN :2072-6643
Sınıflandırma :
12
Assessment of the Effect of High or Low Protein Diet on the Human Urine Metabolome as Measured by NMR.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
S?ren B Engelsen , Arne Astrup , Lars O Dragsted , Thomas M Larsen , Henrik Toft , Francesco Savorani , Hanne Winning , Lone G Rasmussen
Yıl :
2012
Nutrients
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This article is from Nutrients, volume 4. Abstract The objective of this study was to identify urinary metabolite profiles that discriminate between high and low intake of dietary protein during a dietary intervention. Seventy-seven overweight, non-diabetic subjects followed an 8-week low-calorie diet (LCD) and were then randomly assigned to a high (HP) or low (LP) protein diet for 6 months. Twenty-four hours urine samples were collected at baseline (prior to the 8-week LCD) and after dietary intervention; at months 1, 3 and 6, respectively. Metabolite profiling was performed by 1H NMR and chemometrics. Using partial least squares regression (PLS), it was possible to develop excellent prediction models for urinary nitrogen (root mean square error of cross validation (RMSECV) = 1.63 mmol/L; r = 0.89) and urinary creatinine (RMSECV = 0.66 mmol/L; r = 0.98). The obtained high correlations firmly establish the validity of the metabolomic approach since urinary nitrogen is a well established biomarker for daily protein consumption. The models showed that trimethylamine-N-oxide (TMAO) is correlated to urinary nitrogen. Furthermore, urinary creatine was found to be increased by the HP diet whereas citric acid was increased by the LP diet. Despite large variations in individual dietary intake, differentiated metabolite profiles were observed at the dietary group-level.
DOI : doi:10.3390/nu4020112
Cilt :4
ISSN :2072-6643
Sınıflandırma :
13
Apoptosis Inducing Effects of Kuding Tea Polyphenols in Human Buccal Squamous Cell Carcinoma Cell Line BcaCD885.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Li-Hua Qiu , Jia-Le Song , Jing Li , Liang Pang , Xin Zhao
Yıl :
2014
Nutrients
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This article is from Nutrients, volume 6. Abstract Tea polyphenols are functional substances present in tea. Kuding tea as a traditional drink also contains these compounds. After 25, 50 and 100 μg/mL of Kuding tea polyphenol treatment for 48 h, cell proliferation of human buccal squamous cell carcinoma cell line BcaCD885 was inhibited, and the 100 μg/mL of Kuding tea polyphenol showed the highest inhibitory rate at 72.3%. Compared to the lower concentration, the 100 μg/mL of Kuding tea polyphenols significantly (p < 0.05) induced apoptosis as determined by flow cytometry analysis, the content of sub-G1 cancer cells was 32.7%. By RT-PCR and western blot assays, Kuding tea polyphenol significantly induced apoptosis in BcaCD885 cancer cells (p < 0.05) by upregulating caspase-3, caspase-8, caspase-9, Fas/FasL, Bax, p53, p21, E2F1, p73 and downregulating Bcl-2, Bcl-xL, HIAP-1, and HIAP-2 mRNA and protein expressions. Kuding tea polyphenols thus present apoptosis inducing effects in vitro.
DOI : doi:10.3390/nu6083084
Cilt :6
ISSN :2072-6643
14
Anti-Obesity Effects of Onion Extract in Zucker Diabetic Fatty Rats.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Kiharu Igarashi , Yoshiaki Shiojima , Orie Yoshinari
Yıl :
2012
Nutrients
Yayıncı Web Sitesi
Tam Metin
Kaydet Alıntıla
This article is from Nutrients, volume 4. Abstract Anti-obesity effects of onion extract were determined in obesity and diabetes-prone Zucker diabetic fatty rats by measuring the efficacy of markers concerned with diabetes and obesity. Body and adipose tissue weights in 5% of onion extract-fed group were found to be significantly lower than the control group without onion extract. Fasting blood glucose and HOMA-IR levels were also improved, although the serum insulin and leptin levels did not show any remarkable difference. Serum triglyceride and free fatty acid levels in both the 3% and 5%-fed group were found to be reduced compared to the control group. Additionally the feeding of the onion extract increased the glucose tolerance. These results suggest that dietary onion extract is beneficial for improving diabetes by decreasing lipid levels. We also examined differentiation ability of rat white preadipocyte cells using the onion extract and its sulfur-containing components. Cycloalliin, S-methyl-L-cysteine, S-propyl-L-cysteine sulfoxide, dimethyl trisulfide, especially S-methyl-L-cysteine sulfoxide were reported to be effective in inhibiting formation of oil drop in the cells, suggesting that these compounds may be involved in the anti-obesity effect of the onion extract.
DOI : doi:10.3390/nu4101518
Cilt :4
ISSN :2072-6643
Sınıflandırma :
15
Association between Intake of Sugar-Sweetened Beverages and Circulating 25-Hydroxyvitamin D Concentration among Premenopausal Women.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Caroline Diorio , Caroline S Duchaine
Yıl :
2014
Nutrients
Yayıncı Web Sitesi
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Kaydet Alıntıla
This article is from Nutrients, volume 6. Abstract Intake of sugar-sweetened beverages has increased in North America and seems to have several adverse health effects possibly through decreased circulating 25-hydroxyvitamin D (25(OH)D) concentrations. The aim of this cross-sectional study was to evaluate the association between sugar-sweetened beverages intake and 25(OH)D concentrations among premenopausal women. Intake of sugar-sweetened beverages including colas, other carbonated beverages and sweet fruit drinks was assessed using a validated food frequency questionnaire among 741 premenopausal women. Plasma concentrations of 25(OH)D were quantified by radioimmunoassay. The association between sugar-sweetened beverages intake and 25(OH)D concentrations was evaluated using multivariate generalized linear models and Spearman correlations. A higher intake of colas was associated with lower mean 25(OH)D levels (67.0, 63.7, 64.7 and 58.5 nmol/L for never, <1, 1–3 and >3 servings/week, respectively; r = −0.11 (p = 0.004)). A correlation was observed between intake of other carbonated beverages and 25(OH)D concentrations but was not statistically significant (r = −0.06 (p = 0.10)). No association was observed between intake of sweet fruit drinks and 25(OH)D concentrations. This study suggests that high intake of colas may decrease 25(OH)D levels in premenopausal women. Considering the high consumption of these drinks in the general population and the possible consequences of vitamin D deficiency on health, this finding needs further investigation.
DOI : doi:10.3390/nu6082987
Cilt :6
ISSN :2072-6643
16
A High-Dose Shiitake Mushroom Increases Hepatic Accumulation of Triacylglycerol in Rats Fed a High-Fat Diet: Underlying Mechanism.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Xu-Feng Huang , Todd W Mitchell , Simon H J Brown , Jiezhong Chen , Barbara J Meyer , Dian Handayani
Yıl :
2014
Nutrients
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This article is from Nutrients, volume 6. Abstract Shiitake mushroom have been shown to have health benefits including lowering plasma lipids and preventing body weight gain. However, their underlying mechanisms are largely unknown. The study aim was to assess the potential underlying mechanism of Shiitake mushrooms in lowering plasma triacylglycerol (TAG) in rats fed a high fat diet (HFD). Forty Wistar rats were divided into control group were given HFD and treatment group were fed HFD, enriched with Shiitake mushroom powder at a low dose (LD-M): 0.7%, medium dose (MD-M): 2%, or high dose (HD-M): 6% (wt:wt) for six weeks. Diets were isocaloric containing ~50% energy from fat. After six weeks’ dietary intervention, the rats were sacrificed, and blood and tissue samples were collected. The HD-M group showed a significantly higher ratio of liver weight to 100 g body weight (p < 0.05), a more severe hepatic steatosis marker, such as hepatocyte ballooning (p < 0.0001), and more liver triacylglycerol content than LD-M and MD-M (p < 0.05). HD-M also showed a significantly decreased ratio of phosphatidylcholine (PC) to phosphatidylethanolamine (PE) compared to HFD (p < 0.05), however, there were no differences compared to HD-M and MD-M. Our results also showed a positive association between the dosage, liver TAG, and liver ballooning histology. A negative association was found between the mushroom dosage and the ratio of liver PC to PE. This study showed the mechanism of how high-dose Shiitake mushroom (HD-M) prevents obesity by increasing TAG accumulation in the liver, rather than adipose tissue.
DOI : doi:10.3390/nu6020650
Cilt :6
ISSN :2072-6643
17
Hypocholesterolemic Effects of Lactic Acid-Fermented Soymilk on Rats Fed a High Cholesterol Diet.
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e-Kitap
Open Access
Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Mitsuru Fukuda , Shintaro Egusa , Rie Hirahata , Maki Kobayashi
Yıl :
2012
Nutrients
Yayıncı Web Sitesi
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This article is from Nutrients, volume 4. Abstract The effect of fermented soymilk on rats fed a high cholesterol diet was investigated to clarify the cholesterol-lowering function. Male Sprague-Dawley rats aged 7 weeks were fed a control diet (1% cholesterol, high cholesterol diet), high cholesterol diet containing 11.7% fermented soymilk diet (5% soy protein as final concentration, F-5), or high cholesterol diet containing 23.4% fermented soymilk diet (10% soy protein as final concentration, F-10) for 5 weeks. The liver weight and fat mass were decreased by the ingestion of fermented soymilk. The hepatic triglyceride and cholesterol levels in the F-5 and F-10 groups were significantly lowered compared to those in the control group. The plasma total cholesterol level of the F-10 group was significantly decreased. The expression of SREBP-2, a cholesterol synthesis-related gene, was significantly decreased in liver of the F-5 group, but the expression of CYP7a1, a cholesterol catabolism-related gene, was significantly increased. These results suggest that fermented soymilk can modulate the cholesterol metabolism in rats fed a high cholesterol diet.
DOI : doi:10.3390/nu4091304
Cilt :4
ISSN :2072-6643
Sınıflandırma :
18
Antioxidant Properties and Neuroprotective Capacity of Strawberry Tree Fruit (Arbutus unedo) .
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Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Claudia N Santos , Ricardo B Ferreira , Derek Stewart , Gordon McDougall , Paula M Alves , Vera Pontes , Meenu Tyagi , Rui Pimpao , Lucelia Tavares , Sofia Fortalezas
Yıl :
2010
Nutrients
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This article is from Nutrients, volume 2. Abstract Berries contain significant amounts of phytochemicals, including polyphenols, which are reported to reduce cancer risk, coronary heart disease and other degenerative diseases. These effects are mainly attributed to the antioxidant capacity of polyphenols found in berries. Strawberry tree (Arbutus unedo) berries are used in folk medicine but seldom eaten as fresh fruits. Their phenolic profile and antioxidant capacity reveal a high potential, but they are not well characterized as a “health promoting food”. The aim of this study was to assess the antioxidant properties of the edible strawberry tree fruit in vitro and in a neurodegeneration cell model. Raspberry (Rubus idaeus), a well documented health-promoting fruit, was used as a control for comparison purposes. A. unedo yielded a similar content in polyphenols and a slightly lower value of total antioxidant capacity in comparison to R. idaeus. Although the chemically-measured antioxidant activity was similar between both fruits, R. idaeus increased neuroblastoma survival in a neurodegeneration cell model by 36.6% whereas A. unedo extracts caused no effect on neuroblastoma viability. These results clearly demonstrate that a promising level of chemically-determined antioxidant activity of a plant extract is not necessarily correlated with biological significance, as assessed by the effect of A. unedo fruit in a neurodegeneration cell model.
DOI : doi:10.3390/nu2020214
Cilt :2
ISSN :2072-6643
Sınıflandırma :
Kimya %91
Yemek Bilimi %100
19
Estimated Intakes and Sources of Total and Added Sugars in the Canadian Diet.
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Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
John L Sievenpiper , G Harvey Anderson , Sandra L Marsden , Tristin D Brisbois
Yıl :
2014
Nutrients
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This article is from Nutrients, volume 6. Abstract National food supply data and dietary surveys are essential to estimate nutrient intakes and monitor trends, yet there are few published studies estimating added sugars consumption. The purpose of this report was to estimate and trend added sugars intakes and their contribution to total energy intake among Canadians by, first, using Canadian Community Health Survey (CCHS) nutrition survey data of intakes of sugars in foods and beverages, and second, using Statistics Canada availability data and adjusting these for wastage to estimate intakes. Added sugars intakes were estimated from CCHS data by categorizing the sugars content of food groups as either added or naturally occurring. Added sugars accounted for approximately half of total sugars consumed. Annual availability data were obtained from Statistics Canada CANSIM database. Estimates for added sugars were obtained by summing the availability of “sugars and syrups” with availability of “soft drinks” (proxy for high fructose corn syrup) and adjusting for waste. Analysis of both survey and availability data suggests that added sugars average 11%–13% of total energy intake. Availability data indicate that added sugars intakes have been stable or modestly declining as a percent of total energy over the past three decades. Although these are best estimates based on available data, this analysis may encourage the development of better databases to help inform public policy recommendations.
DOI : doi:10.3390/nu6051899
Cilt :6
ISSN :2072-6643
Sınıflandırma :
20
NMR-Based Multi Parametric Quality Control of Fruit Juices: SGF Profiling.
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Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Anna Minoja , Ute C Marx , Fang Fang , Monika Mortter , Hartmut Schafer , Eberhard Humpfer , Susanne Koswig , Peter Rinke , Birk Schutz , Manfred Spraul
Yıl :
2009
Nutrients
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This article is from Nutrients, volume 1. Abstract With SGF Profiling™ we introduce an NMR-based screening method for the quality control of fruit juices. This method has been developed in a joint effort by Bruker BioSpin GmbH and SGF International e.V. The system is fully automated with respect to sample transfer, measurement, data analysis and reporting and is set up on an Avance 400 MHz flow-injection NMR spectrometer. For each fruit juice a multitude of parameters related to quality and authenticity are evaluated simultaneously from a single data set acquired within a few minutes. This multimarker/multi-aspect NMR screening approach features low cost-per-sample and is highly competitive with conventional and targeted fruit juice quality control methods.
DOI : doi:10.3390/nu1020148
Cilt :1
ISSN :2072-6643
Sınıflandırma :
Kimya %100
Yemek Bilimi %81
21
Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases.
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Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
John J Mieyal , Amy L Wilson-Delfosse , William M Johnson
Yıl :
2012
Nutrients
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This article is from Nutrients, volume 4. Abstract Dysregulation of glutathione homeostasis and alterations in glutathione-dependent enzyme activities are increasingly implicated in the induction and progression of neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Huntington’s diseases, amyotrophic lateral sclerosis, and Friedreich’s ataxia. In this review background is provided on the steady-state synthesis, regulation, and transport of glutathione, with primary focus on the brain. A brief overview is presented on the distinct but vital roles of glutathione in cellular maintenance and survival, and on the functions of key glutathione-dependent enzymes. Major contributors to initiation and progression of neurodegenerative diseases are considered, including oxidative stress, protein misfolding, and protein aggregation. In each case examples of key regulatory mechanisms are identified that are sensitive to changes in glutathione redox status and/or in the activities of glutathione-dependent enzymes. Mechanisms of dysregulation of glutathione and/or glutathione-dependent enzymes are discussed that are implicated in pathogenesis of each neurodegenerative disease. Limitations in information or interpretation are identified, and possible avenues for further research are described with an aim to elucidating novel targets for therapeutic interventions. The pros and cons of administration of N-acetylcysteine or glutathione as therapeutic agents for neurodegenerative diseases, as well as the potential utility of serum glutathione as a biomarker, are critically evaluated.
DOI : doi:10.3390/nu4101399
Cilt :4
ISSN :2072-6643
Sınıflandırma :
Biyotıp %100
Nörokimya %55
Apoptoz %29
22
Calcium Absorption in Infants and Small Children: Methods of Determination and Recent Findings .
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Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Steven A Abrams
Yıl :
2010
Nutrients
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This article is from Nutrients, volume 2. Abstract Determining calcium bioavailability is important in establishing dietary calcium requirements. In infants and small children, previously conducted mass balance studies have largely been replaced by stable isotope-based studies. The ability to assess calcium absorption using a relatively short 24-hour urine collection without the need for multiple blood samples or fecal collections is a major advantage to this technique. The results of these studies have demonstrated relatively small differences in calcium absorption efficiency between human milk and currently available cow milk-based infant formulas. In older children with a calcium intake typical of Western diets, calcium absorption is adequate to meet bone mineral accretion requirements.
DOI : doi:10.3390/nu2040474
Cilt :2
ISSN :2072-6643
Sınıflandırma :
23
Neuroprotective Properties of the Marine Carotenoid Astaxanthin and Omega-3 Fatty Acids, and Perspectives for the Natural Combination of Both in Krill Oil.
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Kaynak :
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Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Eduardo F Bondan , Sandra C Poppe , Marcelo P Barros
Yıl :
2014
Nutrients
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This article is from Nutrients, volume 6. Abstract The consumption of marine fishes and general seafood has long been recommended by several medical authorities as a long-term nutritional intervention to preserve mental health, hinder neurodegenerative processes, and sustain cognitive capacities in humans. Most of the neurological benefits provided by frequent seafood consumption comes from adequate uptake of omega-3 and omega-6 polyunsaturated fatty acids, n-3/n-6 PUFAs, and antioxidants. Optimal n-3/n-6 PUFAs ratios allow efficient inflammatory responses that prevent the initiation and progression of many neurological disorders. Moreover, interesting in vivo and clinical studies with the marine antioxidant carotenoid astaxanthin (present in salmon, shrimp, and lobster) have shown promising results against free radical-promoted neurodegenerative processes and cognition loss. This review presents the state-of-the-art applications of n-3/n-6 PUFAs and astaxanthin as nutraceuticals against neurodegenerative diseases associated with exacerbated oxidative stress in CNS. The fundamental “neurohormesis” principle is discussed throughout this paper. Finally, new perspectives for the application of a natural combination of the aforementioned anti-inflammatory and antioxidant agents (found in krill oil) are also presented herewith.
DOI : doi:10.3390/nu6031293
Cilt :6
ISSN :2072-6643
Sınıflandırma :
24
Factors Associated with Exclusive Breastfeeding in Timor-Leste: Findings from Demographic and Health Survey 2009-2010.
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Kaynak :
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Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Andy H Lee , Rajendra Karkee , Jonia Lourenca Nunes Brites da Cruz , Vishnu Khanal
Yıl :
2014
Nutrients
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This article is from Nutrients, volume 6. Abstract Exclusive breastfeeding is known to have nutritional and health benefits. This study investigated factors associated with exclusive breastfeeding among infants aged five months or less in Timor-Leste. The latest data from the national Demographic and Health Survey 2009–2010 were analyzed by binary logistic regression. Of the 975 infants included in the study, overall 49% (95% confidence interval 45.4% to 52.7%) were exclusively breastfed. The exclusive breastfeeding prevalence declined with increasing infant age, from 68.0% at less than one month to 24.9% at five months. Increasing infant age, mothers with a paid occupation, who perceived their newborn as non-average size, and residence in the capital city Dili, were associated with a lower likelihood of exclusive breastfeeding. On the other hand, women who could decide health-related matters tended to breastfeed exclusively, which was not the case for others whose decisions were made by someone else. The results suggested the need of breastfeeding promotion programs to improve the exclusive breastfeeding rate. Antenatal counseling, peer support network, and home visits by health workers could be feasible options to promote exclusive breastfeeding given that the majority of births occur at home.
DOI : doi:10.3390/nu6041691
Cilt :6
ISSN :2072-6643
Sınıflandırma :
25
Inclusion of Pork Meat in the Diets of Young Women Reduces Their Intakes of Energy-Dense, Nutrient-Poor Foods: Results from a Randomized Controlled Tria.
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Kaynak :
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Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Samir Samman , Peter Petocz , Natalie M Gough , Jennifer O Mc
Yıl :
2014
Nutrients
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This article is from Nutrients, volume 6. Abstract Adherence of young women to dietary recommendations has been examined predominantly by surveys. This study aimed to determine the quality of women’s diets relative to the Australian Guide to Healthy Eating (AGHE); and to evaluate dietary changes during an intervention trial with pork meat or an iron supplement. A 12-week randomized trial was conducted in young women who were assigned to one of three groups. They maintained three, seven-day food diaries while continuing their routine diet (CG); taking an iron supplement (SG); or incorporating into their diets 500 g/week of pork (PG). Participants (n = 58) provided dietary information on 1218 diary-days. The serves consumed from the vegetable, fruit and dairy groups were lower (p < 0.001), and from the meat and alternatives group greater (p < 0.001) than the recommended serves. PG consumed significantly fewer (p < 0.001) serves of “extra” foods, and ate fruit more frequently (p < 0.001) than CG and SG. The participants’ dietary self-assessment showed poor agreement with the AGHE description of “serve”. The inclusion of pork in the diets of young women is associated with the reduced consumption of energy-dense nutrient-poor “extra” foods and increased frequency of fruit intake. The effect may be explained by diverse factors such as increased food knowledge, cooking skills and the effect of pork on satiety.
DOI : doi:10.3390/nu6062320
Cilt :6
ISSN :2072-6643
26
Adult Cranberry Beverage Consumers Have Healthier Macronutrient Intakes and Measures of Body Composition Compared to Non-Consumers: National Health and Nutrition Examination Survey (NHANES) 2005-2008.
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Kaynak :
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Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Lisa A Sutherland , Kiyah J Duffey
Yıl :
2013
Nutrients
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This article is from Nutrients, volume 5. Abstract Flavonoids, present in high levels in cranberries, are potent bioactives known for their health-promoting benefits, but cranberry beverages (CB) are not typically recommended as part of a healthy diet. We examine the association between CB consumption with macronutrient intake and weight status. Data for US adults (≥19 years, n = 10,891) were taken from the National Health and Nutrition Examination Survey (NHANES) Survey 2005–2008. Total CB consumption was measured over two non-consecutive 24-h dietary recalls. Linear and logistic regression models adjusting for important covariates were used to examine predicted differences between CB consumers and non-consumers on macronutrient and anthropometric outcomes. Results are weighted to be nationally representative. CB consumers (n = 581) were older (>50 year) non-Hispanic black females. They consumed an average 221 mL (7.5 oz) CB per day. In fully adjusted models CB consumers (vs. non-consumers) had higher carbohydrates and total sugars and lower percent energy from protein and total fat (all p < 0.001), but no difference in total energy. A significantly higher proportion of CB consumers were predicted to be normal weight (BMI < 25 kg/m2; p = 0.001) and had to have lower waist circumferences (p = 0.001). Although there was not a significant trend across level of CB intake, low and middle level CB consumers compared to non-consumers were more likely to be normal weight (p < 0.001) and less likely to be overweight/obese (BMI ≥ 25 kg/m2, p < 0.001). Despite having slightly higher daily macronutrient intakes, CB consumers have more desirable anthropometric measures compared to non-consumers.
DOI : doi:10.3390/nu5124938
Cilt :5
ISSN :2072-6643
27
Protective Effect of Wheat Peptides against Indomethacin-Induced Oxidative Stress in IEC-6 Cells.
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Kaynak :
Internet Archive Books
Dergi:
Nutrients
Yayıncı:
Nutrients
Yazar(lar) :
Guiju Sun , Ligang Yang , Shaokang Wang , Zhixiu Song , Xingchang Pan , Hong Yin
Yıl :
2014
Nutrients
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This article is from Nutrients, volume 6. Abstract Recent studies have demonstrated that wheat peptides protected rats against non-steroidal anti-inflammatory drugs-induced small intestinal epithelial cells damage, but the mechanism of action is unclear. In the present study, an indomethacin-induced oxidative stress model was used to investigate the effect of wheat peptides on the nuclear factor-κB(NF-κB)-inducible nitric oxide synthase-nitric oxide signal pathway in intestinal epithelial cells-6 cells. IEC-6 cells were treated with wheat peptides (0, 125, 500 and 2000 mg/L) for 24 h, followed by 90 mg/L indomethacin for 12 h. Wheat peptides significantly attenuated the indomethacin-induced decrease in superoxide dismutase and glutathione peroxidase activity. Wheat peptides at 2000 mg/L markedly decreased the expression of the NF-κB in response to indomethacin-induced oxidative stress. This study demonstrated that the addition of wheat peptides to a culture medium significantly inhibited the indomethacin-induced release of malondialdehyde and nitrogen monoxide, and increased antioxidant enzyme activity in IEC-6 cells, thereby providing a possible explanation for the protective effect proposed for wheat peptides in the prevention of indomethacin-induced oxidative stress in small intestinal epithelial cells.
DOI : doi:10.3390/nu6020564
Cilt :6
ISSN :2072-6643
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